The development of safe and effective vaccines against COVID-19 has been a turning point in the international effort to control this disease. However, vaccine development is only the first phase of the COVID-19 vaccination process. Correct planning of mass vaccination is important for any policy to immunize the population. For this purpose, it is necessary to set up and properly manage mass vaccination centers. This paper presents a discrete event simulation model of a real COVID-19 mass vaccination center located in Sfax, Tunisia. This model was used to evaluate the management of this center through different performance measures. Three person's arrival scenarios were considered and simulated to verify the response of this real vaccination center to arrival variability. A second model was proposed and simulated to improve the performances of the vaccination center. Like the first model, this one underwent the same evaluation process through the three arrivals scenarios. The simulation results show that both models respond well to the arrival's variability. Indeed, most of the arriving persons are vaccinated on time for all the studied scenarios. In addition, both models present moderate average vaccination and waiting times. However, the average utilization rates of operators are modest and need to be improved. Furthermore, both simulation models show a high average number of persons present in the vaccination center, which goes against the respect of the social distancing condition. Comparison between the two simulation models shows that the proposed model is more efficient than the actual one.

Coronavirus disease (COVID-19) was recognized in December 2019 and spread very severely throughout the world. In 2022 May, the total death numbers reached 6.28 million people worldwide. During the pandemic, some alternative vaccines were discovered in the middle of 2020. Today, many countries are struggling to supply vaccines and vaccinate their citizens. Besides the difficulties of vaccine supply, mass vaccination is a challenging but mandatory task for the countries. Within this context, determining the mass vaccination site is very important for recovering, thus a five-step approach is generated in this paper to solve this real-life problem. Firstly the mass vaccination site selection criteria are determined, and secondly, the spatial data are collected and mapped by using Geographical Information System (GIS) software. Then, the entropy weighting method (EWM) is used for determining the relative importance levels of criteria and fourthly, the multiple attribute utility theory (MAUT) approach is used for ranking the potential mass vaccination sites. Lastly, ranked alternative sites are analyzed using network analyst tool of GIS in terms of covered population. A case study is conducted in Gaziantep city which is the ninth most population and having above-average COVID-19 patients in Turkey. As a result, the fourth alternative (around the Şehitkamil Monument) is chosen as the best mass vaccination site for the city. It is believed that the outcomes of the paper could be used by city planners and decision-makers.

The COVID-19 pandemic was an unexpected and disruptive event that significantly affected the performance of manufacturing systems and supply chains in various sectors. In this paper, a literature review is provided, which investigates the role that Industry 4.0 technologies and simulation tools have played in addressing the effects of the pandemic crisis. Specifically, a bibliometric analysis provides an overview of the most influential technologies through a study of the most used keywords. While a document analysis, conducted on critical papers that concern real case studies, shows that so far simulation provided support in four main areas: energy consumption, healthcare supply chain & contact tracing, food supply chain, and in general supply chain management. The main outcome of this research work is that Industry 4.0 technologies and simulation models were particularly important during the pandemic crisis and their properties deserve to be deeply exploited in the near future.