Minireviews
Copyright ©The Author(s) 2016.
World J Transplant. Dec 24, 2016; 6(4): 682-688
Published online Dec 24, 2016. doi: 10.5500/wjt.v6.i4.682
Table 1 Trials concerned with contrast nephropathy
No.TrialYearNo. of KTRsNeed for HDXCINComments
1Light et al[8]197534Two2220 patients improved after therapy for “graft rejection”
2Moreau et al[12]1975231NoneNilNo increase in risk of CIN in KTRs if contrast studies were performed with normal renal function
3Peters et al[11]198393NoneVery high (84.3%)No increased risk was found > 120 d post-transplant
4Ahuja et al[10]200035None> 21%Patients received high osmolality contrast, and 94% were on CyA therapy
5Charnow et al[16]201576None> 13.2%CIN did not affect allograft function and survival, according to the researchers
6Haider et al[9]2015124None5.60%The largest retrospective study evaluating incidence of CIN in KTRs. CNIs were being used in 95% patients at the time of contrast administration
7Bostock et al[15]201640One12.50%Renal dysfunction is 3 times more frequent in KTR treated with EVAR, though overall survival did not differ between groups. Decreased pre-operative eGFR and higher iodine/eGFR ratio are associated with post-operative renal dysfunction
8Fananapazir et al[14]2016104None7% and 3%Incidence of CNI = 7% (7/104) based on a rise of ≥ 0.3 mg/dL and 3% (3/104) based on a rise of ≥ 0.5 mg/dL. With a strict definition (≥ 0.5 mg/dL) had a pre-CT eGFR < 60 mL/min per 1.73 m2. No patients required DX or had allograft loss 30 d after contrast use