Retrospective Study
Copyright ©The Author(s) 2015.
World J Transplant. Sep 24, 2015; 5(3): 102-109
Published online Sep 24, 2015. doi: 10.5500/wjt.v5.i3.102
Table 1 Demographic features
Peak-PRA 0%-30%
Peak-PRA 31%-60%
Peak-PRA > 60%
SteroidNo steroidSteroidNo steroidSteroidNo steroid
(n = 25218)(n = 7399)(n = 3495)(n = 850)(n = 4966)(n = 923)
Donor factors
Age38 ± 1739 ± 17b37 ± 1738 ± 1835 ± 1535 ± 16
Gender (M/F) %59/4159/4160/4057/4360/4066/34b
Death from CVA (%)4240a3841a3635a
ECD kidney (%)1820d1522d810
DCD kidney (%)7.79.1d6.17.66.78.1
Recipient factors
Age (yr)51 ± 1353 ± 13d37 ± 1738 ± 1747 ± 1349 ± 13
Gender (M/F) %66/3467/3351/4951/4937/6334/66
African American3026d28283331
Diabetes3336d2934b2528
Pre-transplant dialysis (%)9188d8984d9191
Dialysis duration (mo)45 ± 3444 ± 35a49 ± 4247 ± 4261 ± 5159 ± 52
Previous transplant (%)7.34.6d21.814.6d44.237.9d
HLA mismatches3.7 ± 1.83. 7 ± 1.93.5 ± 2.03.1 ± 2.0a3.1 ± 2.03.0 ± 2.0
Transplant- related factors
Cold ischemia (h)18.1 ± 8.118.8 ± 8.0d18.3 ± 7.920.8 ± 10.2d18.4 ± 8.119.3 ± 8.2b
Delayed graft function (%)24.419.5d22.919.6a2620.8b
Table 2 Adjusted overall and death-censored graft failure risks as well as patient death risk for chronic steroid maintenance vs early steroid withdrawal groups in patients ≥ 60 years of age
PRA classAdjusted overall graft failure risk
Adjusted death-censored graft failure risk
Adjusted patient death risk
HR95%CIHR95%CIHR95%CI
0%-30%1.28d1.14-1.471.27b1.10-1.451.43d1.22-1.64
31%-60%1.040.71-1.471.040.70-1.541.200.79-1.81
> 60%0.740.51-1.090.710.48-1.090.760.49-1.19