Living donor outcomes in an emerging living donor liver transplantation program: A single-center experience from Malaysia

Table 1 Evaluation protocol for potential donors in the living donor liver transplantation program at Universiti Malaya Medical Centre[4]

Phase	Evaluation
1	Clinical evaluation: Detailed history (including alcohol consumption) and physical examination. Anthropometric measurements: Height, weight and BMI. Laboratory tests: Blood group, complete blood count, biochemical profile, coagulation profile, FLP, FBS, TFT, ANA, ASMA, caeruloplasmin, tumor markers [AFP, CEA, PSA (male > 50 years), CA 15-3 (female > 40 years)], viral serology (HBsAg, anti-HBs, anti-HBc IgG, anti-HCV, HIV Ag/Ab, VZV IgG, CMV IgG), VDRL test, urine analysis, UPT (for females), FOBT Fibroscan®: CAP and TE
2	Multiphasic CT of the liver: Including volumetry measurements of right and left lobes and liver attenuation, with or without CT of the thorax, abdomen, and pelvis. Cardiac assessment: ECG, echocardiography, with or without EST. Pulmonary assessment: CXR, pulmonary function test. Mammography: Females > 40 years of age
3	Psychological assessment, with or without liver biopsy. Informed consent

Adapted from Rajaram et al[4].

BMI: Body mass index; FLP: Fasting lipid profile; FBS: Fasting blood glucose; TFT: Thyroid function test; ANA: Antinuclear antibody; ASMA: Anti-smooth muscle antibody; AFP: Alpha-fetoprotein; CEA: Carcinoembryonic antigen; PSA: Prostate-specific antigen; HBsAg: Hepatitis B surface antigen; anti-HBs: Hepatitis B surface antibody; IgG: Immunoglobulin G; anti-HCV: Hepatitis C antibody; HIV Ag/Ab: Human immunodeficiency virus antigen/antibody; VZV: Varicella-zoster virus; CMV: Cytomegalovirus; VDRL: Venereal disease research laboratory; UPT: Urine pregnancy test; FOBT: Fecal occult blood test; CAP: Controlled attenuation parameter; TE: Transient elastography; CT: Computed tomography; ECG: Electrocardiogram; CXR: Chest X-ray; EST: Exercise stress test; anti-HBc: Total hepatitis B core antibody; CA: Cancer antigen.

Table 2 Baseline characteristics of living donors

Baseline characteristic	n = 30, n (%)
Type of graft
Left lateral sectionectomy	21 (70.0)
Left hepatectomy	4 (13.3)
Right hepatectomy	5 (16.7)
Age in years
10-19	2 (6.7)
20-29	8 (26.7)
30-39	13 (43.3)
40-49	6 (20.0)
50-59	1 (3.3)
Sex
Male	10 (33.3)
Female	20 (66.7)
Ethnicity
Malay	14 (46.7)
Chinese	13 (43.3)
Indian	1 (3.3)
Other	2 (6.7)
BMI (Asia-Pacific), kg/m2
< 18.5	1 (3.3)
18.5-22.9	15 (50.0)
23.0-24.9	6 (20.0)
25.0-29.9	8 (26.7)
Relationship between donor and recipient
Mother	14 (46.7)
Father	7 (23.3)
Child	2 (6.7)
Siblings	3 (10.0)
Second-degree relatives	4 (13.3)

BMI: Body mass index.