Dai LL, Eni RG, Fu MH, Ba GN. Botanical, chemical, and pharmacological characteristics of Lomatogonium rotatum: A review. World J Pharmacol 2022; 11(2): 6-15 [DOI: 10.5497/wjp.v11.i2.6]
Corresponding Author of This Article
Gen-Na Ba, PhD, Professor, School of Mongolian Medicine, Inner Mongolia Minzu University, No. 996 Xilamulun Street, Horqin District, Tongliao 028000, Inner Mongolia Autonomous Region, China. bagenna@126.com
Research Domain of This Article
Medicine, Research & Experimental
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Pharmacol. Jun 16, 2022; 11(2): 6-15 Published online Jun 16, 2022. doi: 10.5497/wjp.v11.i2.6
Botanical, chemical, and pharmacological characteristics of Lomatogonium rotatum: A review
Li-Li Dai, Rong-Gui Eni, Ming-Hai Fu, Gen-Na Ba
Li-Li Dai, Ming-Hai Fu, Gen-Na Ba, School of Mongolian Medicine, Inner Mongolia Minzu University, Tongliao 028000, Inner Mongolia Autonomous Region, China
Rong-Gui Eni, NMPA Key Laboratory of Quality Control of Traditional Chinese Medicine (Mongolian Medicine), Inner Mongolia Minzu University, Tongliao 028000, Inner Mongolia Autonomous Region, China
Author contributions: Dai LL and Eni RG performed the data collection and wrote the manuscript; Fu MH and Ba GN wrote and reviewed the manuscript.
Supported byNational Natural Science Foundation of China, No. 81803845; Natural Science Foundation of Inner Mongolia Autonomous Region, No. 2018MS08040; Construction Project of "Inner Mongolia Autonomous Region Mongolian Medicine and Food Source Protection and Utilization Innovation Team", No. 190301; and Graduate Research Project of Inner Mongolia Minzu University, No. NMDBS1901.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Gen-Na Ba, PhD, Professor, School of Mongolian Medicine, Inner Mongolia Minzu University, No. 996 Xilamulun Street, Horqin District, Tongliao 028000, Inner Mongolia Autonomous Region, China. bagenna@126.com
Received: January 18, 2022 Peer-review started: January 18, 2022 First decision: February 8, 2022 Revised: February 19, 2022 Accepted: May 17, 2022 Article in press: May 17, 2022 Published online: June 16, 2022
Core Tip
Core Tip: As a highly distinctive Mongolian medicinal herb, Lomatogonium rotatum (L. rotatum) Fries ex Nym is traditionally used to prevent and treat liver and gallbladder diseases. However, its clinical application value and further development are limited by strict requirements on its growing environment, high demand for medicinal materials, decrease in wild resources, and insufficient scientific and technological availability in ethnic minority areas. Currently, a total of 38 compounds have been isolated and identified from L. rotatum Fries ex Nym, with flavonoids, xanthones, and terpenoids being the main metabolites. Pharmacological studies have mainly focused on hepatitis, liver injury, and weight loss, but mechanisms of pharmacological activity remain elusive and further comprehensive in vivo and in vivo experimental designs are needed to elucidate these issues.
