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Copyright ©The Author(s) 2022.
World J Exp Med. Sep 20, 2022; 12(5): 92-99
Published online Sep 20, 2022. doi: 10.5493/wjem.v12.i5.92
Table 1 Outcomes of bariatric surgery in patients with a history of organ transplants
Organ
Type of bariatric surgery
Patients (n)
Potential risks
Mean BMI or weight changes after BS
Comorbidities/improvements
Ref.
LiverRYGB7Gastric staple line leakage, EWLFrom 44.34 ± 6.08 kg/m2 to 26.47 ± 5.53 kg/m2DM, HTN, GERD, vascular disease, and OSAAl-Nowaylati et al[17]
LSG12Infections and leaksMean BMI decrease 12.9 kg/m2Nine out of 12 patients had DM and metabolic syndrome; four out of 12 patients showed a complete improvement after LSGTsamalaidze et al[27]
Open SG1-From 47 kg/m2 to 29.8 kg/m2DM and arterial HTNButte et al[28]
RYGB, LSG, jejunoileal bypass SG11Organ insufficiencyMean BMI 28.3 ± 5.8 kg/m2 Early surgical site infection, and bleedingSafwan et al[29]
KidneyGastric bypass5-Mean WL of 33 kgDM, HTN, and hyperlipidemiaArias et al[11]
RYGB, LSG5-50% EWL at 2 yrDM, HTN, hyperlipidemia, polycystic ovarian syndrome, peripheral vascular disease, and CHFSzomstein et al[7]
LSG10Acute renal failure and sleeve stricture57% EWL at 6 mo, and 75% EWL at 12 moNot mentionedGolomb et al[30]
6-44.1% EWL at 3 mo, and 75.9% EWL at 12 moMorbid obesityGazzetta et al[31]
Liver and kidneyLSG9Mesh dehiscence after a synchronous incisional hernia repair, bile leakage, and dysphagia that required reoperation61% EWLMesh dehiscence after synchronous incisional hernia repair, bile leak, post-operative dysphagiaLin et al[18]
HeartRYGB and LSG2-From 37.5 kg/m2 to 27.5 kg/m2 at 12 moHTN, hiperlipidemia, anemia, and hipomagnesemiaTsamalaidze et al[32]
Heart and kidneyVertical banded gastroplasty2Inadvertent laceration of the pancreas resulting in pseudocyst which may need percutaneous and then surgical drainageMean WL of 54 and 56 kgNot mentionedRex et al[33]
Table 2 Dose adjustment of immunosuppressive drugs following bariatric surgery in patients with a history of organ transplants
Organ
Type of bariatric surgery
Patients (n)
Immunosuppressant adjustment compared to patients without organ transplants
Ref.
LiverLSG12No changesTsamalaidze et al[27]
9Lin et al[18]
Bariatric surgery56Lazzati et al[34]
KidneyGastric bypass2Increased doses of sirolimus, tacrolimus, and mycophenolate mofetilRogers et al[35]
Laparoscopic gastric bypass5No changesArias et al[11]
LSG10Two patients with increased doses of tacrolimus and one decreased Golomb et al[30]
6No changesGazzetta et al[31]
5Decreased dose of cyclosporineSzomstein et al[7]
Biliopancreatic diversion1No changesLópez Deogracias et al[36]
HeartLaparoscopic gastric banding, laparoscopic robotic-assisted RYGB, and LSG3No changesTsamalaidze et al[32], Ablassmaier et al[37]
Heart and kidneyVertical banded gastroplasty1Changes based on serum levelRex et al[33]