Role of LIGHT in the pathogenesis of joint destruction in rheumatoid arthritis
Afsie Sabokbar, Sara Afrough, David J Mahoney, Yoshinobu Uchihara, Catherine Swales, Nicholas A Athanasou, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Nuffield Orthopaedic Centre, Oxford OX3 7HE, United Kingdom
Author contributions: All authors contributed equally to this work; Sabokbar A, Mahoney DJ and Uchihara Y performed the research; Swales C contributed clinical materials; Sabokbar A, Afrough S, Mahoney DJ, Uchihara Y and Athanasou NA analysed the data; Sabokbar A, Afrough S, Mahoney DJ and Athanasou NA wrote the paper and approved the final version of the article to be published.
Supported by the Rosetrees Trust, No. 242; and Arthritis Research Campaign (United Kingdom), No. 18358.
Institutional review board statement: All synovial studies and synovial fluid samples were taken from patients after informed consent and ethical permission was obtained for participation in this study. The research Ethics were granted by National Research Ethics Committee (Oxfordshire), REC reference number C01.070.
Institutional animal care and use committee statement: Not applicable.
Conflict-of-interest statement: To the best of our knowledge, no conflict of interest exists.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Nicholas A Athanasou, MD, PhD, FRC (Path), Professor of Musculoskeletal Pathology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Nuffield Orthopaedic Centre, Windmill Rd, Oxford OX3 7HE, United Kingdom. firstname.lastname@example.org
Telephone: +44-1865-738136 Fax: +44-1865-738140
Received: January 26, 2017
Peer-review started: February 8, 2017
First decision: March 8, 2017
Revised: April 26, 2017
Accepted: May 3, 2017
Article in press: May 5, 2017
Published online: May 20, 2017