Incidental gallbladder mucocele mimicking acute cholecystitis: A case report and review of literature

Table 1 Summary of the 27 cases reported in literature

Ref.	Demographics and clinical presentation	Kawasaki disease	Gallstones	Histopathology	Complications	Imaging	Management
Pack and Teng[12], 1968	61-year-old male with cystic duct carcinoma	No	No	Mucosal flattening, ulceration, and inflammation		Cholecystography	Cholecystectomy and cystic mass removal
Magilavy et al[24], 1978	6-year-old female with fever and sore throat	Yes	No			Ultrasound	Methicillin
Magilavy et al[24], 1978	8-year-old male with swollen cervical lymph node and fever	Yes	No	Fibrinous exudate and inflammation		Ultrasound, laparotomy	Cholecystectomy
Kumari et al[29], 1979	5-year-old male with fever, swollen cervical lymph nodes, rash, and vomiting	Yes	No			Ultrasound	Cholecystectomy
Liebmann et al[17], 1982	25-year-old male with malaise, left anterior cervical neck pain and swelling, sore throat, and nonproductive cough	Yes	No			Ultrasound	Erythromycin
McCrindle et al[30], 1988	3.5-year-old male with Henoch-Schoenlein syndrome; presenting with cough, RUQ pain, rhinorrhea, vomiting, and generalized aches	No	No			Ultrasound	Prednisone
Bishop and Kao[21], 1991	6-year-old male with periumbilical pain, fever, and vomiting	Yes	No			Ultrasound, HIDA scan	IVIG
Crankson et al[31], 1992	6-year-old male with liver cirrhosis secondary to giant cell hepatitis; presenting with RUQ pain, vomiting, and diarrhea	No	No			Ultrasound	Cholecystostomy; patient expired due to cardiopulmonary arrest
Westrope and Acharya[20], 2001	3-year-old female with cryptosporidium infection; presenting with vomiting and malodorous watery diarrhea	No	No	Hepatobiliary involvement by cryptosporidium infection		Ultrasound	Fluids and antibiotics
Herek and Yildiran[23], 2001	8-year-old male with abdominal pain status post nonpenetrating trauma to RUQ	No	No	Gallbladder mucosa with ulcerations		Ultrasound	Blood transfusion and cholecystectomy
Khothsymuong and Kaminski[4], 2004	Elderly man (age not reported) with malaise, chest pain, and weight loss	No	Yes			Ultrasound	Patient expired
Egritas et al[16], 2007	3-month-old female with fever and inappetence	Yes	No			Ultrasound	IVIG
Gucev et al[13], 2011	24-year-old male with Wilson’s disease; presenting with RUQ pain and mass, swelling of the right talocrural articulation	No	No			Ultrasound	Cholecystectomy; penicillamine; alpha tocopherol, and vitamins B, K and C
Zong et al[11], 2013	55-year-old female with RUQ mass, abdominal distention, and epigastric discomfort	No	No	Gallbladder wall lined by columnar epithelium; inflammation		Ultrasound	Laparotomy and drainage
Aldaghi et al[22], 2015	5-year-old male with jaundice, fever, vomiting, and RUQ pain	No	No		Viral hepatitis	Ultrasound	Antibiotics: Ceftizoxime and metronidazole
Albu et al[32], 2016	52-year-old male RUQ pain, fever, fatigue, and weakness	No	Yes		Simultaneous toxic hepatitis	Ultrasound	Laparoscopic cholecystectomy
Clemente et al[19], 2017	53-year-old female with right hypochondrium pain	No	No	Heterotopic intestinal mucosa		Ultrasound and CT	Laparoscopic cholecystectomy
Yadav and Kankaria[33], 2017	46-year-old female with RUQ pain	No	Yes	Chronic cholecystitis		Ultrasound	Laparoscopic cholecystectomy
Reyes et al[34], 2017	39-year-old female RUQ pain with postprandial epigastric pain	No	Yes	Suppurative gallbladder mucocele, acute on chronic cholecystitis		Ultrasound and MRCP	Laparoscopic cholecystectomy
Chaly et al[18], 2017	48-year-old male with liver transplantation; presenting with RUQ pain	No	No	Inflammation, fibrosis, and granulation tissue formation		MRCP, ERCP, and CT	Laparoscopic cholecystectomy
Sun et al[25], 2018	6-year-old male with Kawasaki disease; presenting with fever, rash, stiff neck, diffuse abdominal pain, fatigue, and acholic stool	Yes	No			Ultrasound	IVIG and aspirin for treatment of Kawasaki disease
Kılıç et al[35], 2018	7-year-old male with RUQ pain, fever, vomiting, and diarrhea	Yes	No			Ultrasound	IVIG and aspirin for treatment of Kawasaki disease
Loh et al[14], 2019	63-year-old male with inappetence, weight loss, and intermittent vomiting	No	Yes		Gastric outlet obstruction	CT and MRCP	Open cholecystectomy
Valecha[15], 2019	27-year-old female abdominal pain, vomiting, and lack of appetite	No	Yes	Fibrosis of the wall		Ultrasound	Laparoscopic cholecystectomy
Sharma et al[36], 2021	50-year-old female with RUQ pain	No	Yes			CT and ultrasound	Morphine and ondansetron
Ganta et al[37], 2022	67-year-old female RUQ and mid abdominal pain, nausea, vomiting	No	Yes			Ultrasound, MRCP	Laparoscopic cholecystectomy
Le et al[10], 2023	56-year-old female lower abdominal pressure, nausea, indigestion, and urinary urgency	No	Yes	Fibrosis, inflammation, thickened muscularis propria, Rokitansky-Aschoff sinuses, and attenuated mucosa		Ultrasound and CT	Laparoscopic cholecystectomy and intraoperative cholangiogram

RUQ: Right upper quadrant; HIDA: Hepatobiliary iminodiacetic acid; IVIG: Intravenous immunoglobulin; CT: Computed tomography; MRCP: Magnetic resonance cholangiopancreatography.