Basic Study
Copyright ©The Author(s) 2017.
World J Exp Med. Aug 20, 2017; 7(3): 84-96
Published online Aug 20, 2017. doi: 10.5493/wjem.v7.i3.84
Figure 2
Figure 2 Increased percentage of Th17 cells within limited cutaneous systemic sclerosis subset vs healthy controls. A: Percentage of Th17 cells for lcSSc (n = 11), dcSSc (n = 13), and healthy controls (n = 16) is presented. Increased percentage of Th17 cells within lcSSc patients as opposed to controls, respectively, 20.46% ± 2.41% vs 13.73% ± 1.21%, P = 0.025. Boxplots are expressed as means ± SD; B-D: Panel B depicts the flow cytometric analysis of Th17 cells. A representative patient with lcSSc phenotype is shown. The lymphocytes were gated according to their physical characteristics (FSC and SSC) in R1; afterwards T helper cells (CD3+CD4+) were gated in R2. T helpers, which were detected double positive for CD161 and CD196 surface expression (R3, upper right quadrant) were defined as Th17 cells. lcSSc: Limited cutaneous systemic sclerosis.