Copyright ©The Author(s) 2015.
World J Exp Med. Aug 20, 2015; 5(3): 164-181
Published online Aug 20, 2015. doi: 10.5493/wjem.v5.i3.164
Figure 2
Figure 2 Latent tuberculosis pathogenesis and transmission profile. Most people are adequately protected by innate immunity against MTB infection, however, the infection progresses when the innate immune response levels are inadequate. The development of specific immunity leads to the containment of MTB in granulomas as asymptomatic latent infection. However, inadequate adaptive response at any time progresses to the reactivation and development of full-blown active tuberculosis. MTB: Mycobacterium tuberculosis.