Review
Copyright ©The Author(s) 2019.
World J Crit Care Medl. Sep 11, 2019; 8(5): 59-71
Published online Sep 11, 2019. doi: 10.5492/wjccm.v8.i5.59
Table 1 Summary of current evidence on biomarkers and their role in the evaluation and management of community acquired pneumonia[22]
RoleBiomarker
DiagnosisCRP, PCT, Ang 1, Ang 2
Severity of illnessCRP, PCT, Ang 1, Ang 2, Pro-ADM, Pro-ANP, Pro-VNP, SP-D, YKL-40, CCL 18, Endocan, NETs, FGF21,
Clinical instabilityCRP, PCT, NETs, FGF21
De-escalation antibioticPCT
PrognosticationCRP, PCT, Ang 1, Ang 2, Pro-ADM, Pro-ANP, Pro-VNP, SP-D, YKL-40, CCL 18, NETs, FGF21
Table 2 Biomarkers in acute respiratory distress syndrome[44]
PathwaysBiomarkers
EpithelialRAGE
SP-D
KL-6
CC16
KGF
EndothelialAng-1/2
vWF
VEGF
InflammatoryPro-inflammatoryIL-1β
IL-6
TNFα
IL-8
IL-18
Anti-InflammatoryILRA
sTNF-RI/II
IL-10
Coagulation and FibrinolysisPAI-1