Intensive care outcome of left main stem disease surgery: A single center three years’ experience

Table 1 Description of the studied group

Variable	n	Minimum	Maximum	mean ± SD
Age	399	18	79	51.9 ± 11.3
BMI (kg/m2)	399	18.8	43.7	25.1 ± 7.1
Creatinine (μmol/L)	397	54.9	378.1	99.8 ± 55.8
EF%	388	18	65	45.8 ± 8.9
Additive Euro score	398	0	19	4.6 ± 3.1
CPB time (min)	393	0	377	118.1 ± 46.9
ACC time (min)	392	0	188	86.1 ± 38.7
Anesthesia time (min)	398	220	630	295.7 ± 71.2
VIS	398	0	29	6 ± 2.1
LOSICU (h)	397	26	320	65.9 ± 46.1
LOV (min)	397	190	17300	432 ± 65
LOShosp (d)	394	6	245	28.1 ± 12.9

BMI: Body mass index; EF: Ejection fraction; CPB: Cardiopulmonary bypass; ACC: Aortic cross clamp; WBCs: White blood cells; LOS_ICU: Length of stay in intensive care unit; LOV: Length of mechanical ventilation; LOS_hosp: Hospital length of stay; VIS: Vasoactive inotrope score.

Table 2 Demographic differences between both groups

Variable	Group I (LMS), 75 (%)	Group II (no LMS), 324 (%)	P value
Age	58.3 ± 11.8	55.19 ± 9.7	0.06
Gender (male)	62 (82.6)	264 (81.4)	0.34
Diabetes	39 (52)	144 (44.4)	0.05
Hypertension	32 (42.6)	144 (44.4)	0.13
Euro score	5.8 ± 3.9	5.0 ± 3.6	0.6
BMI	30.1 ± 6.3	27.9 ± 5.8	0.6
EF < 40	24 (32)	86 (26.5)	0.07
IABP	28 (37.3)	80 (24.6)	0.05
Elective surgery	45 (60)	224 (66.6)	0.5
Basal creatinine (μmol/L)	98.7 ± 46.5	94.7 ± 43.1	0.6

BMI: Body mass index; EF: Ejection fraction; IABP: Intra-aortic balloon pump; LMS: Left main stem.

Table 3 Main differences in both studied groups

Variable	Group I (LMS), 75 (%)	Group II (no LMS), 324 (%)	P value
Inotrops
Dopamine, mean dose (μg/kg/min), mean ± SD	9 (12), 6.50 ± 3.10	31 (9.6), 7.23 ± 15.2	0.5, 0.34
Adrenaline, mean dose (μg/kg/min), mean ± SD	6 (8), 0.06 ± 0.01	27 (8.3), 0.05 ± 0.009	0.6, 0.8
Noradrenline, mean dose (μg/kg/min), mean ± SD	12 (16), 0.08 ± 0.01	43 (13.2), 0.07 ± 0.008	0.4, 0.7
Dobutamine, mean dose (μg/kg/min), mean ± SD	4 (5.3), 4.5 ± 1.4	11 (3.3), 3.9 ± 1.1	0.06, 0.09
Milrinone, mean dose (μg/kg/min), mean ± SD	3 (4), 0.56 ± 0.05	7 (2.1), 0.6 ± 0.04	0.9, 0.4
Intraoperative parameters
CPB time (min)	139 ± 43	125 ± 69.6	0.6
ACC time (min)	87.1 ± 34	79.3 ± 30.1	0.9
Anesthesia time (min)	6.6 ± 1.4	6.5 ± 1.8	0.9
Grafts	3.1 ± 0.8	3.4 ± 1.01	0.7
Postoperative parameters
LOV (min)	384.1 ± 123	375.1 ± 119	0.8
LOSICU (h)	65.9 ± 46.1	63.4 ± 43.9	0.6
LOShosp (d)	16.1 ± 4.2	14.7 ± 3.7	0.6
VIS	6.4 ± 2.6	6.1 ± 2.2	0.4
Post-operative outcome
POAF	12 (16)	39 (12)	0.06
AKI	20 (26.7)	75 (23.1)	0.09
In-hospital-mortality	2 (2.7)	7 (2.1)	0.8
VAP	1 (1.3)	5 (1.5)	0.7
VA-ECMO	2 (2.7)	4 (1.2)	0.08
Re-admission ICU	2 (2.7)	8 (2.5)	0.8
Re-exploration	6 (8)	26 (8.6)	0.5
PMI	3 (4)	11 (3.3)	0.4

AKI: Acute kidney injury; CPB: Cardiopulmonary bypass; ACC: Aortic cross clamp; ECMO: Extracorporeal membrane oxygenation; LOV: Length of mechanical ventilation; LOS_ICU: Length of stay in intensive care unit; LOS_hosp: Hospital length of stay; POAF: Post-operative atrial fibrillation; VIS: Vasoactive inotrope score; VAP: Ventilator associated pneumonia.