Has Stewart approach improved our ability to diagnose acid-base disorders in critically ill patients?

Figure 3 Regression and Bland and Altman analysis between metabolic parameters of different approaches in seven normal volunteers. A: Lineal regression between base excess and strong ion difference; B: Agreement between base excess and strong ion difference; C: Lineal regression between albumin-corrected anion gap and strong ion gap; D: Agreement between albumin-corrected anion gap and strong ion gap; Panel B and D display the relationship between the mean value and the difference of both measurements. The lines indicate the mean difference between both parameters (bias) ± 2 SD (95% limits of agreement). Modified from Dubin et al[37].