Copyright ©The Author(s) 2016.
World J Surg Proced. Mar 28, 2016; 6(1): 13-18
Published online Mar 28, 2016. doi: 10.5412/wjsp.v6.i1.13
Table 1 List of select genes that can be found on multi-gene panels and associated cancer risks
GeneCancer risk1
ATMBreast, pancreatic cancer
BRCA1Breast, ovarian, male breast cancer, melanoma, pancreatic cancer
BRCA2Breast, ovarian, male breast cancer, melanoma, pancreatic, prostate cancer
CDH1Breast, diffuse-type gastric cancer
CHEK2Breast, colon, ovarian
EPCAMColorectal, uterine, stomach, ovarian
MLH1Colorectal, uterine, stomach, ovarian
MSH2Colorectal, uterine, ovarian
MSH6Colorectal, uterine, stomach, ovarian
MUTYHBreast, colorectal, other gastrointestinal sites
NF1Breast, peripheral nerve sheath tumors, gliomas, leukemias, pheochromocytomas
PALB2Breast, pancreatic cancer
PMS2Colorectal, uterine, stomach, ovarian
PTENBreast, thyroid, endometrial cancer
RAD51CBreast, ovarian
RAD51DBreast, ovarian
STK11Breast, gastrointestinal, ovarian
TP53Breast, ovarian, osteosarcomas, brain tumors, colorectal, other gastrointestinal sites