Copyright ©The Author(s) 2015.
World J Immunol. Nov 27, 2015; 5(3): 113-130
Published online Nov 27, 2015. doi: 10.5411/wji.v5.i3.113
Figure 4
Figure 4 CD11c+ dendritic cell are involved in the host response to transplanted hydrogels. CD11c+ DC were detected in re-epithelialized layers surrounding RHCIII hydrogels transplanted in murine corneas, 22 d post transplantation (A, B). CD11c+ dendritic cells infiltrated hydrogels transplanted into murine corneas as early as 6 h (C) or 24 h (D, E) after transplantation and showed a transformation in morphology from rounded immature DC to well-differentiated DC at the latter time point after interacting with the three dimensional crosslinked collagen matrix. Images were taken within the hydrogel in (C-E) as shown in the schematic. DAPI: Nuclear staining shown in blue; CD11c in magenta; DC: Dendritic cell.