Copyright ©2013 Baishideng.
World J Clin Pediatr. Feb 8, 2013; 2(1): 1-5
Published online Feb 8, 2013. doi: 10.5409/wjcp.v2.i1.1
Table 1 Reference doses (mg/kg) compared to intravenous formulations to illustrate the need for sequential dilutions in neonates
Active agentAvailable concentrationReference dosesPreterm, 1.5 kgTerm, 3 kg
Amikacin, adult vial500 mg/2 mL15-20 mg/kg130 mg, 0.12 mL50 mg, 0.2 mL
Amikacin, pediatric vial100 mg/2 mL15-20 mg/kg30 mg, 0.6 mL50 mg, 1.0 mL
Enoxaparin40 mg/0.4 mL1 mg/kg11.5 mg, 0.015 mL13 mg, 0.03 mL
Erythromycin1000 mg/20 mL5-10 mg/kg12 mg, 0.24 mL25 mg, 0.5 mL
Fentanyl100 μg/2 mL1-3 μg/kg13 μg, 0.06 mL16 μg, 0.12 mL
Insulin300 U/3 mL0.1-1 U/kg per hour10.3 U, 0.03 mL10.6 U, 0.06 mL
Midazolam15 mg/3 mL0.1 mg/kg10.15 mg, 0.03 mL10.3 mg, 0.06 mL
Paracetamol500 mg/50 mL10 mg/kg15 mg, 1.5 mL30 mg, 3 mL
Phenobarbital200 mg/1 mL5 mg/kg17.5 mg, 0.0375 mL115 mg, 0.075 mL
Propofol200 mg/20 mL1-3 mg/kg2 mg, 0.2 mL4.5 mg, 0.45 mL
Ranitidine50 mg/2 mL0.5-1 mg/kg11.5 mg, 0.06 mL13 mg, 0.12 mL