|
1
|
Fasih P, Yari A, Kamali Hakim L, Kashe NN. Artificial Intelligence in Detecting and Segmenting Vertical Misfit of Prosthesis in Radiographic Images of Dental Implants: A Cross-Sectional Analysis. Clin Oral Implants Res 2025; 36:578-588. [PMID: 39840554 DOI: 10.1111/clr.14406] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/09/2024] [Revised: 12/24/2024] [Accepted: 01/13/2025] [Indexed: 01/23/2025]
Abstract
OBJECTIVE This study evaluated ResNet-50 and U-Net models for detecting and segmenting vertical misfit in dental implant crowns using periapical radiographic images. METHODS Periapical radiographs of dental implant crowns were classified by two experts based on the presence of vertical misfit (reference group). The misfit area was manually annotated in images exhibiting vertical misfit. The resulting datasets were utilized to train the ResNet-50 and U-Net deep learning models. Then, 70% of the images were allocated for training, while the remaining 30% were used for validation and testing. Five general dentists categorized the testing images as "misfit" or "fit." Inter-rater reliability with Cohen's kappa index and performance metrics were calculated. The average performance metrics of dentists and artificial intelligence (AI) were compared using the paired-samples t test. RESULTS A total of 638 radiographs were collected. The kappa values between dentists and AI ranged from 0.93 to 0.98, indicating perfect agreement. The ResNet-50 model achieved accuracy and precision of 92.7% and 87.5%, respectively, whereas dentists had a mean accuracy of 93.3% and precision of 89.6%. The sensitivity and specificity for AI were 90.3% and 93.8%, respectively, compared to 90.1% and 95.1% for dentists. The Dice coefficient yielded 88.9% for the ResNet-50 and 89.5% among the dentists. The U-Net algorithm produced a loss of 0.01 and an accuracy of 0.98. No significant difference was found between the average performance metrics of dentists and AI (p > 0.05). CONCLUSION AI can detect and segment vertical misfit of implant prosthetic crowns in periapical radiographs, comparable to clinician performance.
Collapse
Affiliation(s)
- Paniz Fasih
- Department of Prosthodontics, School of Dentistry, Kashan University of Medical Sciences, Kashan, Iran
| | - Amir Yari
- Department of Oral and Maxillofacial Surgery, School of Dentistry, Kashan University of Medical Sciences, Kashan, Iran
| | | | - Nader Nasim Kashe
- Department of Oral and Maxillofacial Radiology, School of Dentistry, Kashan University of Medical Sciences, Kashan, Iran
| |
Collapse
|
|
2
|
Suito H, Yoshihara H, Maeda N, Kasai R, Inoue T, Amano M, Oku Y, Fujimoto K, Nagao K. Evaluation of the effect of reducing metal artifacts in multi-detector CT imaging of zirconia and titanium implants. Oral Radiol 2025:10.1007/s11282-025-00814-5. [PMID: 40038165 DOI: 10.1007/s11282-025-00814-5] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/28/2024] [Accepted: 02/17/2025] [Indexed: 03/06/2025]
Abstract
OBJECTIVES Zirconia oral implants produce larger artifacts on computed tomography (CT) compared to titanium oral implants. This study aimed to compare the effectiveness of metal artifact reduction (MAR) software and dual-energy (DE) methods, which are used in multi-detector CT (MDCT) to reduce the artifacts produced by titanium and zirconia oral implants. METHODS Oral implants were placed in the lower right second premolar and second molar regions of an acrylic mandible model and evaluated using MDCT. For MAR, Single Energy Metal Artifact Reaction (SEMAR) images were obtained, and for DE, images were obtained at 135 keV. The evaluation was based on 21 regions of interest (ROIs) with sides of 2.8 mm, set at 15, 25, and 35 mm from the center (the lower-right first premolar), with 65°, 90°, 115°, and 145° angles set on the buccal and lingual sides. The evaluation was based on an Artifact Index (AI). RESULTS The lingual aspect of the AI tended to be larger compared to the buccal aspect, regardless of the image-processing method. In addition, the SEMAR method tended to have a greater artifact reduction effect than the DE method. The distortion of the mandibular model and occurrence of new artifacts were confirmed using SEMAR. CONCLUSIONS SEMAR had higher artifact reduction effects on metal artifacts than the DE method. Although SEMAR and dual-energy methods can effectively reduce metal artifacts, they also cause false images and areas that cannot be observed. Therefore, diagnostic and treatment planning, including imaging, is essential before artifact reduction processing.
Collapse
Affiliation(s)
- Hideki Suito
- Department of Oral and Maxillofacial Radiology, Graduate School of Biomedical Sciences, Tokushima University, 3-18-15 Kuramoto, Tokushima, 770-8504, Japan.
| | - Hozumi Yoshihara
- Department of Oral and Maxillofacial Radiology, Graduate School of Biomedical Sciences, Tokushima University, 3-18-15 Kuramoto, Tokushima, 770-8504, Japan
| | - Naoki Maeda
- Department of Oral and Maxillofacial Radiology, Graduate School of Biomedical Sciences, Tokushima University, 3-18-15 Kuramoto, Tokushima, 770-8504, Japan
| | - Ryosuke Kasai
- Department of Medical Imaging/Nuclear Medicine, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan
| | - Tadashi Inoue
- Department of Clinical Technology, Division of Radiology, Tokushima University Hospital, Tokushima, Japan
| | - Masafumi Amano
- Department of Clinical Technology, Division of Radiology, Tokushima University Hospital, Tokushima, Japan
| | - Yuuri Oku
- Department of Prosthodontics and Oral Rehabilitation, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan
| | - Keiko Fujimoto
- Department of Prosthodontics and Oral Rehabilitation, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan
| | - Kan Nagao
- Department of Prosthodontics and Oral Rehabilitation, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan
| |
Collapse
|
|
3
|
Roccuzzo A, Thomann I, Wyss A, Schütz S, Zumstein T, Sculean A, Salvi GE, Imber JC, Stähli A. Long-Term Clinical and Radiographic Outcomes of Hydrophilic Implants: A 10-Year Study in a Specialist Private Practice. Clin Implant Dent Relat Res 2025; 27:e13415. [PMID: 39529414 DOI: 10.1111/cid.13415] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/19/2024] [Revised: 10/18/2024] [Accepted: 10/21/2024] [Indexed: 11/16/2024]
Abstract
AIM To report the 10-year clinical and radiographic outcomes of implants placed in grafted (GBR) and non-grafted (no-GBR) sites in a Swiss specialist private practice using hydrophilic implants with a low surface roughness flange. METHODS Fifty consecutively enrolled patients received 159 hydrophilic implants with a low surface roughness flange. A first re-evaluation was performed 1 year after delivery of restoration (T1). An additional examination was performed at the 10-year follow-up (T2) including the assessment of clinical (i.e., periodontal/peri-implant pockets probing depths (PPD) (mm), full-mouth bleeding score (%), implant survival rate, mid-buccal keratinized mucosa (KM) width in mm, and peri-implant phenotype), and radiographic (i.e., marginal bone level change [ΔMBL]) outcomes. Biological, mechanical and technical complications were also recorded. RESULTS Out of the initial cohort, 22 patients (9/40.9% male and 13/59% female) and 63 implants (47 with GBR, 16 without GBR), could be re-examined at T2. Overall, ΔMBL (T2-T1) was -0.56 ± 0.96 mm. In the GBR group, ΔMBL were significantly higher at the distal sites compared to the no-GBR group (-0.75 ± 1.17 mm vs. -0.12 ± 1.29 mm, p = 0.045), however, in the GBR group MBL started at a higher level at T1 but were similar with the no-GBR group at T2. Implant survival was 100% with only very few technical complications (6.3%). Mean PPD amounted to 3.84 ± 1.00 mm with significantly higher values in the GBR group (3.98 ± 1.08 mm vs. 3.45 ± 0.60 mm; p = 0.016). Nineteen implants (30.1%) were diagnosed with peri-implant health while 44 (69.9%) presented with peri-implant mucositis. CONCLUSION Within the limitations of this study, favorable clinical and radiographic conditions were recorded around hydrophilic implants with a low surface roughness flange placed in pristine and augmented bone after 10 years in function.
Collapse
Affiliation(s)
- Andrea Roccuzzo
- Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland
- Unit for Practice-Based Research, School of Dental Medicine, University of Bern, Bern, Switzerland
| | - Isabel Thomann
- Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland
| | - Amanda Wyss
- Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland
| | | | | | - Anton Sculean
- Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland
| | - Giovanni E Salvi
- Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland
| | - Jean-Claude Imber
- Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland
| | - Alexandra Stähli
- Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland
| |
Collapse
|
|
4
|
Silveira TMD, Silva DNDA, Casarin M, Monajemzadeh S, Chalmers J, Pirih FQ. Evaluation of Bone Loss in Implants Adjacent to a Tooth or Edentulous Area in Peri-Implantitis and Control Murine Models. J ORAL IMPLANTOL 2025; 51:98-104. [PMID: 39731390 DOI: 10.1563/aaid-joi-d-24-00100] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 12/29/2024]
Abstract
Peri-implantitis (PI) is an inflammatory disease that affects supportive tissues around dental implants, and its progression eventually leads to bone loss and implant failure. However, PI effects may be different based on the presence or absence of adjacent teeth. The objective was to investigate the differences in bone loss and inflammation between implants placed adjacent to a tooth or edentulous area in a ligature-induced PI model. Materials and methods include the following: Three-week-old C57BL/6J male mice underwent maxillary first (AT; n = 12) or first and second (AE; n = 8) left molar extractions. In both groups, implants were placed in the first molar region 8 weeks after tooth extraction. Each group was further divided into control (C) or ligature (PI) 4 weeks after osseointegration. The mice were euthanized 12-14 days after ligature placement. The samples were analyzed using micro-computed tomography and histology. Statistical analysis was performed using analysis of variance and Tukey multiple comparison test (P < .05). Radiographic linear analysis revealed no statistically significant differences in bone levels between the two C and PI groups. Linear bone loss was significantly greater in the PI group than in the C group. Volumetric analysis yielded similar results. Histologically, hematoxylin and eosin staining revealed no notable differences between the two C and PI groups. The PI groups showed increased levels of inflammatory infiltrates and bone resorption. Qualitative assessment of collagen through picrosirius red staining demonstrated increased collagen disorganization in the PI group compared with that in the C group. No notable differences were observed between the AT and AE groups. The presence or absence of an adjacent tooth does not influence PI-induced soft and hard tissue alterations.
Collapse
Affiliation(s)
- Taciane Menezes da Silveira
- School of Dentistry, Section of Periodontics, University of California, Los Angeles, Los Angeles, California, United States
- School of Dentistry, Department of Periodontology, Federal University of Pelotas, Pelotas, Rio Grande do Sul, Brazil
| | - Davi Neto de Araújo Silva
- School of Dentistry, Section of Periodontics, University of California, Los Angeles, Los Angeles, California, United States
| | - Maísa Casarin
- School of Dentistry, Department of Periodontology, Federal University of Pelotas, Pelotas, Rio Grande do Sul, Brazil
| | - Sepehr Monajemzadeh
- School of Dentistry, Section of Periodontics, University of California, Los Angeles, Los Angeles, California, United States
| | - Jaclyn Chalmers
- School of Dentistry, Section of Periodontics, University of California, Los Angeles, Los Angeles, California, United States
| | - Flavia Q Pirih
- School of Dentistry, Section of Periodontics, University of California, Los Angeles, Los Angeles, California, United States
| |
Collapse
|
|
5
|
Windael S, Collaert B, De Buyser S, Vervaeke S, De Bruyn H. A 10-year Retrospective Clinical Study to Identify Risk Indicators for Peri-Implant Bone Loss and Implant Failure. Clin Oral Implants Res 2025; 36:202-219. [PMID: 39440793 DOI: 10.1111/clr.14375] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/01/2023] [Revised: 09/08/2024] [Accepted: 10/09/2024] [Indexed: 10/25/2024]
Abstract
AIM To evaluate long-term survival and success of dental implants and evaluate indicators affecting the long-term outcome. MATERIALS AND METHODS Implant survival, success and crestal bone loss (BL) over time were evaluated. For covariates at patient level, Kaplan-Meier estimates of implant survival were compared between groups with the log-rank test. Observed mean bone loss (MBL) was plotted as a function of time. Cumulative frequencies of BL were plotted for different post-op times. Uni- and multivariate analysis was performed. Simple linear mixed and multiple linear mixed models for BL at 1, 5 and 10 years were fitted. RESULTS 407 patients (221 women, 186 men; mean age 64.86 years (range 28-92, SD 10.11)), with 1482 implants, responded. Absolute implant survival was 94.74%; MBL was 0.81 mm (SD 1.58, range 0.00-17.00) after an average follow-up of 10.66 years (range 10-14, SD 0.87). Implant survival was influenced on implant level by smoking, implant width and early bone loss (EBL) > 0.5 mm; on patient level by a history of periodontitis. Indicators influencing MBL after the 1st year were abutment height, type of surgery and implant width, while after 5 and 10 years of function were abutment height, EBL > 0.5 mm and smoking. CONCLUSION Implant survival was significantly affected by a history of periodontitis on patient level and by smoking, implant width and EBL > 0.5 mm on implant level. Late bone loss was significantly affected by abutment height, EBL > 0.5 mm and smoking. TRIAL REGISTRATION B670201524796.
Collapse
Affiliation(s)
- Simon Windael
- Faculty of Medicine and Health Sciences, School of Dental Medicine, Department of Periodontology and Oral Implantology, Ghent University, Ghent, Belgium
| | - Bruno Collaert
- Center for Periodontology and Implantology Leuven, Heverlee, Belgium
| | - Stefanie De Buyser
- Biostatistics Unit, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium
| | - Stijn Vervaeke
- Faculty of Medicine and Health Sciences, School of Dental Medicine, Department of Periodontology and Oral Implantology, Ghent University, Ghent, Belgium
- Private Practice Periodontology and Oral Implantology, Geluwe, Belgium
| | - Hugo De Bruyn
- Faculty of Medicine and Health Sciences, School of Dental Medicine, Department of Periodontology and Oral Implantology, Ghent University, Ghent, Belgium
- Department of Reconstructive Oral Care, Academic Centre for Dentistry Amsterdam (ACTA), Universiteit van Amsterdam and Vrije Universiteit, Amsterdam, The Netherlands
| |
Collapse
|
|
6
|
Velasco-Ortega E, Pato-Mourelo J, López-López B, Monsalve-Guil L, Moreno-Muñoz J, López-López J, Núñez-Márquez E, Matos Garrido N, Rondón-Romero JL, Jiménez-Guerra Á, Ortiz-García I. Long-Term Clinical Study on Sandblasted-Acid-Etched Surface Dental Implants: 12-Year Follow-Up. MATERIALS (BASEL, SWITZERLAND) 2025; 18:183. [PMID: 39795828 PMCID: PMC11722049 DOI: 10.3390/ma18010183] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Subscribe] [Scholar Register] [Received: 11/30/2024] [Revised: 12/23/2024] [Accepted: 12/30/2024] [Indexed: 01/13/2025]
Abstract
Sandblasting and acid etching are common procedures used to treat implant surfaces, enhancing osseointegration and improving clinical success rates. This clinical study aimed to evaluate the long-term outcomes of sandblasted and acid-etched implants. A total of 303 implants were placed in 114 partially and totally edentulous patients using a two-stage surgical technique and an early loading protocol (6-8 weeks). Clinical findings for implants and prosthetics were evaluated over a 12-year follow-up period. A total of 12 implants (3.9%) failed, with 3 failures occurring during the healing period before loading and 9 due to peri-implantitis. The cumulative survival rate for all implants was 96.1%. A total of 156 prostheses were placed on 300 implants, 87 single crowns, 45 partial fixed bridges, 9 full-arch fixed restorations, and 15 overdentures. The mean marginal bone loss was 1.18 mm. (SD. 0.64 mm.). Thirty-nine implants (13%) in twenty-four patients exhibited peri-implantitis. Technical complications, including prosthetic screw loosening or fracture, ceramic chipping, and acrylic fractures, were observed in 24 subjects (21.1%). Sandblasted and acid-etched surface implants placed in the maxilla and mandible reported favorable outcomes and stable tissue conditions with an early loading protocol.
Collapse
Affiliation(s)
- Eugenio Velasco-Ortega
- Comprehensive Dentistry for Adults and Gerodontology, Faculty of Dentistry, University of Seville, 41009 Seville, Spain; (E.V.-O.); (J.P.-M.); (B.L.-L.); (L.M.-G.); (J.M.-M.); (E.N.-M.); (N.M.G.); (J.L.R.-R.); (I.O.-G.)
| | - Jesús Pato-Mourelo
- Comprehensive Dentistry for Adults and Gerodontology, Faculty of Dentistry, University of Seville, 41009 Seville, Spain; (E.V.-O.); (J.P.-M.); (B.L.-L.); (L.M.-G.); (J.M.-M.); (E.N.-M.); (N.M.G.); (J.L.R.-R.); (I.O.-G.)
| | - Borja López-López
- Comprehensive Dentistry for Adults and Gerodontology, Faculty of Dentistry, University of Seville, 41009 Seville, Spain; (E.V.-O.); (J.P.-M.); (B.L.-L.); (L.M.-G.); (J.M.-M.); (E.N.-M.); (N.M.G.); (J.L.R.-R.); (I.O.-G.)
| | - Loreto Monsalve-Guil
- Comprehensive Dentistry for Adults and Gerodontology, Faculty of Dentistry, University of Seville, 41009 Seville, Spain; (E.V.-O.); (J.P.-M.); (B.L.-L.); (L.M.-G.); (J.M.-M.); (E.N.-M.); (N.M.G.); (J.L.R.-R.); (I.O.-G.)
| | - Jesús Moreno-Muñoz
- Comprehensive Dentistry for Adults and Gerodontology, Faculty of Dentistry, University of Seville, 41009 Seville, Spain; (E.V.-O.); (J.P.-M.); (B.L.-L.); (L.M.-G.); (J.M.-M.); (E.N.-M.); (N.M.G.); (J.L.R.-R.); (I.O.-G.)
| | - José López-López
- Faculty of Dentistry, Service of the Medical-Surgical Area of Dentistry Hospital, 41009 Seville, Spain
- L’Hospitalet de Llobregat, University of Barcelona, 08970 Barcelona, Spain
| | - Enrique Núñez-Márquez
- Comprehensive Dentistry for Adults and Gerodontology, Faculty of Dentistry, University of Seville, 41009 Seville, Spain; (E.V.-O.); (J.P.-M.); (B.L.-L.); (L.M.-G.); (J.M.-M.); (E.N.-M.); (N.M.G.); (J.L.R.-R.); (I.O.-G.)
| | - Nuno Matos Garrido
- Comprehensive Dentistry for Adults and Gerodontology, Faculty of Dentistry, University of Seville, 41009 Seville, Spain; (E.V.-O.); (J.P.-M.); (B.L.-L.); (L.M.-G.); (J.M.-M.); (E.N.-M.); (N.M.G.); (J.L.R.-R.); (I.O.-G.)
| | - José Luis Rondón-Romero
- Comprehensive Dentistry for Adults and Gerodontology, Faculty of Dentistry, University of Seville, 41009 Seville, Spain; (E.V.-O.); (J.P.-M.); (B.L.-L.); (L.M.-G.); (J.M.-M.); (E.N.-M.); (N.M.G.); (J.L.R.-R.); (I.O.-G.)
| | - Álvaro Jiménez-Guerra
- Comprehensive Dentistry for Adults and Gerodontology, Faculty of Dentistry, University of Seville, 41009 Seville, Spain; (E.V.-O.); (J.P.-M.); (B.L.-L.); (L.M.-G.); (J.M.-M.); (E.N.-M.); (N.M.G.); (J.L.R.-R.); (I.O.-G.)
| | - Iván Ortiz-García
- Comprehensive Dentistry for Adults and Gerodontology, Faculty of Dentistry, University of Seville, 41009 Seville, Spain; (E.V.-O.); (J.P.-M.); (B.L.-L.); (L.M.-G.); (J.M.-M.); (E.N.-M.); (N.M.G.); (J.L.R.-R.); (I.O.-G.)
| |
Collapse
|
|
7
|
Yu X, Lin X, Wang F, Wu Y. LONG-TERM PREDICTIVE VALUE OF BLEEDING ON PROBING IN PERI‑IMPLANTITIS DIAGNOSIS: A SYSTEMATIC REVIEW AND META-ANALYSIS. J Evid Based Dent Pract 2024; 24:102034. [PMID: 39631968 DOI: 10.1016/j.jebdp.2024.102034] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/11/2024] [Revised: 08/14/2024] [Accepted: 08/18/2024] [Indexed: 12/07/2024]
Abstract
OBJECTIVE This systematic review and meta-analysis aimed to evaluate the diagnostic value of bleeding on probing (BOP) for peri‑implantitis detection on implant- and patient-levels, as reported in prospective and retrospective studies with at least 5 years of follow-up. MATERIALS AND METHODS A systematic search of 3 electronic databases was conducted and supplemented with a hand-search to identify clinical studies that reported the prevalence of peri‑implantitis and BOP after at least 5 years of functional loading. Random-effects meta-analyses were conducted to combine the proportions of peri‑implantitis among BOP positive implants and patients across studies. Heterogeneity was explored with subgroup analyses. RESULTS 5826 patients and 17,198 implants were included in this review. Definitions of peri‑implantitis varied between studies. Thirty studies were included for assessment. Implant-level meta-analysis was conducted in 24 studies and patient-level meta-analysis in 19 studies. Overall proportion of peri‑implantitis in BOP-positive implants was 26.5% (95% CI, 21.2 to 32.1) and 35.1% (95% CI, 27.4 to 43.1) in BOP-positive patients. Substantial heterogeneity was present, and prediction intervals were 5.2%-56% and 6.4%-71.5% at the implant- and patient-level, respectively. CONCLUSION Within the limitations, prevalence of peri‑implantitis was found to be around 1 third in both BOP-positive implants and patients. Prevalence varied between studies. Although a guiding clinical factor in the diagnosis of peri‑implantitis, clinicians should be aware of the significant false-positive rates of BOP.
Collapse
Affiliation(s)
- Xinbo Yu
- Second Dental Center, National Clinical Research Center for Oral Diseases, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
| | - Xinyan Lin
- Second Dental Center, National Clinical Research Center for Oral Diseases, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
| | - Feng Wang
- Second Dental Center, National Clinical Research Center for Oral Diseases, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
| | - Yiqun Wu
- Second Dental Center, National Clinical Research Center for Oral Diseases, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
| |
Collapse
|
|
8
|
Lee SY, Daher R, Jung J, Han K, Sailer I, Lee J. Risk of Late Implant Loss and Peri-Implantitis Based on Dental Implant Surfaces and Abutment Types: A Nationwide Cohort Study in the Elderly. J Clin Periodontol 2024; 51:1574-1585. [PMID: 39406495 PMCID: PMC11651715 DOI: 10.1111/jcpe.14079] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/09/2024] [Revised: 09/21/2024] [Accepted: 10/02/2024] [Indexed: 12/19/2024]
Abstract
AIM This nationwide population-based cohort study aimed to assess the incidence of implant complication treatments, including implant removal procedures and peri-implantitis treatments, in relation to implant surfaces and abutment types. METHODS Data from the National Health Insurance Service, covering approximately 50 million individuals, were used. Implants and abutments were categorized by codes, including surfaces such as resorbable blasting media, sandblasted large grit and acid-etched (SA) and hydroxyapatite coating, along with abutment structures (one-piece straight, two-piece straight, angled). The incidence of implant complication treatments was analysed using Kaplan-Meier curves and Cox proportional hazards regression (α = 0.05). RESULTS The study included 2,354,706 implants. The SA group had the lowest hazard ratio for implant removal procedures (p < 0.0001). No significant differences were found in the risk of peri-implantitis treatments between implant surfaces (p = 0.0587). The risk of implant complication treatments did not differ significantly by the abutment type (p = 0.9542). The incidence rate of implant complication treatments was < 3.9 per 1000 implant-years across all groups. CONCLUSIONS The SA group showed a slightly lower risk of late implant loss, whereas no significant association was found for the abutment type groups. All implant and abutment type groups showed an incidence rate of < 3.9 per 1000 implant-years for complication treatments.
Collapse
Affiliation(s)
- Su Young Lee
- Department of Prosthodontics, Seoul St. Mary's Dental Hospital, College of MedicineThe Catholic University of KoreaSeoulRepublic of Korea
| | - René Daher
- Division of Cariology and Endodontology, University Clinics of Dental MedicineUniversity of GenevaGenevaSwitzerland
| | - Jin‐Hyung Jung
- Department of Biostatistics, College of MedicineThe Catholic University of KoreaSeoulRepublic of Korea
| | - Kyungdo Han
- Department of Statistics and Actuarial ScienceSoongsil UniversitySeoulRepublic of Korea
| | - Irena Sailer
- Division of Fixed Prosthodontics, University Clinics of Dental MedicineUniversity of GenevaGenevaSwitzerland
| | - Jae‐Hyun Lee
- Department of ProsthodonticsSeoul National University School of DentistrySeoulRepublic of Korea
- Dental Research InstituteSeoul National University School of DentistrySeoulRepublic of Korea
| |
Collapse
|
|
9
|
Zhang R, Hao X, Zhang K. Evaluation of two different occlusal patterns on single posterior implant-supported crowns: A 12-month prospective study of occlusal analysis. J Prosthet Dent 2024; 132:1277-1284. [PMID: 36610845 DOI: 10.1016/j.prosdent.2022.11.026] [Citation(s) in RCA: 3] [Impact Index Per Article: 3.0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/31/2022] [Revised: 11/04/2022] [Accepted: 11/04/2022] [Indexed: 01/07/2023]
Abstract
STATEMENT OF PROBLEM According to the concept of implant-protected occlusion, light occlusion and late contact could prevent implants from occlusal overload. However, clinical data demonstrating how light occlusion differs from normal occlusion are lacking. PURPOSE The purpose of this prospective clinical study was to characterize the occlusal variation of single posterior implant-supported crowns with or without light occlusion. MATERIAL AND METHODS Participants with a single missing posterior maxillary or mandibular molar who were to receive implant-supported zirconia ceramic crowns were enrolled. The participants were divided into a light occlusion group, in which a 12-μm articulating film could be removed from the implant-supported crown and opposing natural teeth under the intercuspal position, and a normal occlusion group, in which the articulating film could not be removed. All participants underwent occlusal examinations using the T-scan III system, answered a satisfaction questionnaire using a visual analog scale (VAS), and received regular follow-ups. The participants were evaluated at 0.5, 3, 6, and 12 months after implant-supported crown delivery. The relative occlusal force of the implant-supported crowns, mesial teeth, control teeth (corresponding natural tooth on the dentition contralateral to each implant), and the occlusal contact time of implant-supported crowns were recorded. Moreover, the asymmetry index of the occlusal force and the VAS score were calculated. Two independent-sample tests were used to compare the 2 groups. The Wilcoxon rank sum and Mann‒Whitney tests were used to compare nonnormally distributed data (α=.001). RESULTS Fifty study participants with a mean ±standard deviation age of 36.97 ±7.34 years (23 men and 27 women aged 20 to 50 years) were followed for 0.5 to 12 months. No obvious complications of overloading were observed in either group. The mean ±standard deviation of the relative occlusal force of implant-supported crowns in the light occlusion group (from 4.91 ±3.52% to 10.34 ±4.35%) was always lower than that in the normal occlusion group (from 10.45 ±4.32% to 18.15 ±4.80%), while the mean ±standard deviation of the occlusal contact time in the light occlusion group (from 0.38 ±0.26 seconds to 0.10 ±0.07 seconds) was significantly later than that in the normal occlusion group (from 0.12 ±0.08 seconds to 0.04 ±0.02 seconds) (P<.001). The value of the asymmetry index of occlusal force remained within the normal range (10%). The VAS score in the normal occlusion group was significantly higher than that in the light occlusion group (P<.001). CONCLUSIONS Providing light occlusion to reduce occlusal force and delay the contact time was not stable over time. The relative occlusal force and occlusal contact time showed a similar development trend in both groups, and no obvious signs of occlusal overloading were observed in this study. Long-term follow-up is necessary for implant-supported prostheses because of the continuous increase in occlusal force.
Collapse
Affiliation(s)
- Ru Zhang
- Attending, Department of Prosthodontics, Capital Medical University School of Stomatology, Beijing Stomatological Hospital, Beijing, PR China
| | - Xiaoyu Hao
- Graduate Student, Department of Prosthodontics, Capital Medical University School of Stomatology, Beijing Stomatological Hospital, Beijing, PR China
| | - Kaiyu Zhang
- Associate Chief, Department of Oral and Maxillofacial Surgery, Capital Medical University School of Stomatology, Beijing Stomatological Hospital, Beijing, PR China.
| |
Collapse
|
|
10
|
Imber JC, Khandanpour A, Roccuzzo A, Irani DR, Bosshardt DD, Sculean A, Pippenger BE. Comparative osseointegration of hydrophobic tissue-level tapered implants-A preclinical in vivo study. Clin Oral Implants Res 2024; 35:1299-1309. [PMID: 39032079 DOI: 10.1111/clr.14318] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/10/2023] [Revised: 05/16/2024] [Accepted: 06/04/2024] [Indexed: 07/22/2024]
Abstract
PURPOSE To histometrically compare the osseointegration and crestal bone healing of a novel tapered, self-cutting tissue-level test implant with a standard tissue-level control implant in a submerged healing regimen. MATERIALS AND METHODS In a mandibular minipig model, implants were inserted and evaluated histometrically after a healing period of 3, 6, and 12 weeks. The primary outcome was the evaluation of bone-to-implant contact (BIC) and secondary outcomes were primary stability as per insertion torque and first BIC (fBIC). Outcomes for the test and control implants were compared using Wilcoxon signed-rank tests and mixed linear regression models. RESULTS Insertion torque values were significantly higher for the test (50.0 ± 26.4 Ncm) compared to the control implants (35.2 ± 19.7 Ncm, p = .0071). BIC values of test implants were non-inferior to those of control implants over the investigated study period. After 12 weeks, the corresponding values measured were 81.62 ± 11.12% and 90.41 ± 4.81% (p = .1763) for test and control implants, respectively. Similarly, no statistical difference was found for fBIC values, except for the 12 weeks outcome that showed statistically lower values for the test (-675.58 ± 590.88 μm) compared to control implants (-182.75 ± 197.40 μm, p = .0068). CONCLUSIONS Novel self-cutting tissue-level implants demonstrated noninferior osseointegration and crestal bone height maintenance to the tissue-level implants. Histometric outcomes between both implants demonstrated test implants were statistically noninferior to control implants, despite substantial differences in the bone engagement mechanism and resulting differences in insertion torque and qualitative bone healing patterns.
Collapse
Affiliation(s)
- Jean-Claude Imber
- Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland
| | - Azita Khandanpour
- Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland
| | - Andrea Roccuzzo
- Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland
| | - Delia R Irani
- Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland
| | - Dieter D Bosshardt
- Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland
| | - Anton Sculean
- Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland
| | - Benjamin E Pippenger
- Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland
- Department of Preclinical Research, Institut Straumann AG, Basel, Switzerland
| |
Collapse
|
|
11
|
Park WB, Seol HK, Shin S, Hong JY. Surgical Drainage and Simultaneous Sinus Floor Augmentation in Patients with Chronic Maxillary Sinusitis. MEDICINA (KAUNAS, LITHUANIA) 2024; 60:1256. [PMID: 39202537 PMCID: PMC11356457 DOI: 10.3390/medicina60081256] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Figures] [Subscribe] [Scholar Register] [Received: 06/28/2024] [Revised: 07/25/2024] [Accepted: 07/31/2024] [Indexed: 09/03/2024]
Abstract
Chronic maxillary sinusitis accompanied by severe thickening of the sinus mucosa, blockage of the ostium, and patient-reported symptoms requires preoperative assessment and treatment by an otolaryngologist before maxillary sinus floor augmentation (MSFA). Prescription of antibiotics and nasal saline irrigation are the first choice of treatment; however, endoscopic sinus surgery is considered when the treatment's effect is limited and drug resistance is observed. Nevertheless, MSFA performed in the presence of sinus pathologies have been reported to have favorable results when the lesions are managed properly. This report presents cases of two patients who required MSFA but were diagnosed with chronic maxillary sinusitis (case 1 with nasal sinusitis and case 2 with dental sinusitis). After 2 weeks of antibiotic therapy, endoscopic surgery was recommended due to minimal changes in the size of the sinus lesion; however, the patients refused because of improved self-reported symptoms. Therefore, intraoral surgical drainage was planned as an alternative treatment. A large bony window was prepared at the lateral wall of the maxillary sinus, and a long intentional incision was made to improve access for the suction tip in various directions and depths into the sinus cavity. Thorough suction of the purulent exudate and saline irrigation were performed through this access. The size of the perforated area was reduced along with the elevation of the Schneiderian membrane from the sinus floor, and simultaneous bone grafting with implant placement was performed. Prosthesis was delivered after 6-8 months. At 1-year follow-up after loading, favorable outcomes of implant survival and maintenance of augmented bone height were observed, with no recurrence of postoperative sinusitis. Within the limitations of the present case report, thorough sinus drainage and saline irrigation during maxillary sinus floor augmentation resolved sinus infection in patients with chronic maxillary sinusitis with short-term clinical outcomes.
Collapse
Affiliation(s)
- Won-Bae Park
- Private Practice in Periodontics and Implant Dentistry, Seoul 02771, Republic of Korea;
| | - Hye-Kyoung Seol
- Department of Dentistry, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea;
| | - Seungil Shin
- Department of Periodontology, College of Dentistry, Kyung Hee University Dental Hospital, Kyung Hee University, Seoul 02447, Republic of Korea;
| | - Ji-Youn Hong
- Department of Periodontology, College of Dentistry, Kyung Hee University Dental Hospital, Kyung Hee University, Seoul 02447, Republic of Korea;
| |
Collapse
|
|
12
|
Liu Y, Shen Z, Xu Y, Zhu YW, Chen W, Qiu J. Layer-by-layer self-assembly of PLL/CPP-ACP multilayer on SLA titanium surface: Enhancing osseointegration and antibacterial activity in vitro and in vivo. Colloids Surf B Biointerfaces 2024; 240:113966. [PMID: 38781846 DOI: 10.1016/j.colsurfb.2024.113966] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/31/2023] [Revised: 05/03/2024] [Accepted: 05/11/2024] [Indexed: 05/25/2024]
Abstract
Dental Implants are expected to possess both excellent osteointegration and antibacterial activity because poor osseointegration and infection are two major causes of titanium implant failure. In this study, we constructed layer-by-layer self-assembly films consisting of anionic casein phosphopeptides-amorphous calcium phosphate (CPP-ACP) and cationic poly (L-lysine) (PLL) on sandblasted and acid etched (SLA) titanium surfaces and evaluated their osseointegration and antibacterial performance in vitro and in vivo. The surface properties were examined, including microstructure, elemental composition, wettability, and Ca2+ ion release. The impact the surfaces had on the adhesion, proliferation and differentiation abilities of MC3T3-E1 cells were investigated, as well as the material's antibacterial performance after exposure to the oral microorganisms such as Porphyromonas gingivalis (P. g) and Actinobacillus actinomycetemcomitans (A. a). For the in vivo studies, SLA and Ti (PLL/CA-3.0)10 implants were inserted into the extraction socket immediately after extracting the rabbit mandibular anterior teeth with or without exposure to mixed bacteria solution (P. g & A. a). Three rabbits in each group were sacrificed to collect samples at 2, 4, and 6 weeks of post-implantation, respectively. Radiographic and histomorphometry examinations were performed to evaluate the implant osseointegration. The modified titanium surfaces were successfully prepared and appeared as a compact nano-structure with high hydrophilicity. In particular, the Ti (PLL/CA-3.0)10 surface was able to continuously release Ca2+ ions. From the in vitro and in vivo studies, the modified titanium surfaces expressed enhanced osteogenic and antibacterial properties. Hence, the PLL/CPP-ACP multilayer coating on titanium surfaces was constructed via a layer-by-layer self-assembly technology, possibly improving the biofunctionalization of Ti-based dental implants.
Collapse
Affiliation(s)
- Yao Liu
- Department of Oral Implantology, Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China; Jiangsu Province Key Laboratory of Oral Diseases, Nanjing, China
| | - Zhe Shen
- Department of Oral Implantology, Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China; Jiangsu Province Key Laboratory of Oral Diseases, Nanjing, China
| | - Yan Xu
- Department of Oral Implantology, Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China; Jiangsu Province Key Laboratory of Oral Diseases, Nanjing, China
| | - Ya-Wen Zhu
- Department of Oral Implantology, Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China; Jiangsu Province Key Laboratory of Oral Diseases, Nanjing, China
| | - Wei Chen
- Department of Oral Implantology, Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China; Jiangsu Province Key Laboratory of Oral Diseases, Nanjing, China
| | - Jing Qiu
- Department of Oral Implantology, Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China; Jiangsu Province Key Laboratory of Oral Diseases, Nanjing, China; Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing, China.
| |
Collapse
|
|
13
|
Steyer E, Theisen K, Hulla H, Ubaidha Maheen C, Sokolowski A, Lorenzoni M. Eleven- to fifteen-year outcome for two-piece implants with an internal tube-in-tube connection: a cross-sectional analysis of 245 implants. Oral Maxillofac Surg 2024; 28:859-867. [PMID: 38315402 DOI: 10.1007/s10006-024-01215-4] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/09/2023] [Accepted: 01/19/2024] [Indexed: 02/07/2024]
Abstract
PURPOSE The aim of this retrospective study was to evaluate the outcomes of a two-piece implant system with a tube-in-tube internal connection after up to 15 years of clinical use. MATERIAL AND METHODS A retrospective follow-up examination of patients treated with internal tube-in-tube implants between 2003 and 2006 was conducted. The implant survival rates, peri-implant conditions (marginal bone loss, bleeding on probing, plaque index, probing depth), and technical complications were determined. RESULTS In total, 312 dental implants were placed in 152 patients. Of the original 152 patients enrolled, 245 implants in 112 patients were available for a follow-up evaluation after 11 to 15 years (mean observation time, 12.9 ± 1.1 years). The overall implant survival rate was 93.9%. Outcomes for MBL (1.49 ± 1.23 mm), PI (24.3 ± 22.2%), BOP (18.3 ± 28.7%), and PD (2.74 ± 1.21 mm) were observed. Selected parameters (time after implant surgery, smoking habits, bone augmentation (GBR)) showed an influence on MBL and PD. CONCLUSIONS The internal tube-in-tube implant system showed favorable long-term results. The correlation of MBL and PD with the patient-specific factor smoking habit is in accordance with other studies. CLINICAL RELEVANCE Camlog Root-Line implants with a tube-in-tube implant-abutment connection and a 1.6-mm polished neck configuration have demonstrated favorable long-term outcomes in daily clinical practice. However, it is important to note that these implants are no longer available on the market.
Collapse
Affiliation(s)
- Elisabeth Steyer
- Division of Operative Dentistry, Periodontology and Prosthodontics, Department of Dental Medicine and Oral Health, Medical University of Graz, Billrothgasse 4, 8010, Graz, Austria
| | - Kerstin Theisen
- Division of Operative Dentistry, Periodontology and Prosthodontics, Department of Dental Medicine and Oral Health, Medical University of Graz, Billrothgasse 4, 8010, Graz, Austria.
| | - Helfried Hulla
- Division of Operative Dentistry, Periodontology and Prosthodontics, Department of Dental Medicine and Oral Health, Medical University of Graz, Billrothgasse 4, 8010, Graz, Austria
- Private Practice Straß, Graz, Austria
| | - Ceeneena Ubaidha Maheen
- Division of Operative Dentistry, Periodontology and Prosthodontics, Department of Dental Medicine and Oral Health, Medical University of Graz, Billrothgasse 4, 8010, Graz, Austria
| | - Alwin Sokolowski
- Division of Operative Dentistry, Periodontology and Prosthodontics, Department of Dental Medicine and Oral Health, Medical University of Graz, Billrothgasse 4, 8010, Graz, Austria
| | - Martin Lorenzoni
- Division of Operative Dentistry, Periodontology and Prosthodontics, Department of Dental Medicine and Oral Health, Medical University of Graz, Billrothgasse 4, 8010, Graz, Austria
| |
Collapse
|
|
14
|
Guney Z, Altingoz SM, Has H, Serdar MA, Kurgan S. The impact of electronic cigarettes on peri-implant health: A systematic review and meta-analysis. J Dent 2024; 143:104883. [PMID: 38360396 DOI: 10.1016/j.jdent.2024.104883] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/12/2023] [Revised: 02/05/2024] [Accepted: 02/06/2024] [Indexed: 02/17/2024] Open
Abstract
OBJECTIVES Recent literature suggests that the use of electronic cigarette (e-cigarette) is a substantial contributing factor to the unsuccessful outcomes of dental implant procedures. Our aim was to systematically review the effect of e-cigarette use on clinical (PI, PD, BOP), radiographic (bone loss), and immunologic (IL-1β) peri‑implant parameters. DATA Main search terms used in combination: electronic cigarette, peri‑implantitis, vaping. SOURCES An electronic search was undertaken for MEDLINE, EMBASE, COCHRANE, and SCOPUS databases between 2017 and 2023. STUDY SELECTION The study protocol was developed according to PRISMA guidelines, and the focus question was formulated according to the PICO strategy. No restriction was accepted regarding language or year to avoid selection bias; the initial database search yielded 49 publications. Following the selection process, only seven studies met the inclusion criteria. Seven studies were statistically analyzed via MedCalc program. A pooled effect was deemed statistically significant if the p-value was less than 0.05. CONCLUSION Electronic cigarettes cause an increase in probing depth, bone loss, and the level of IL-1β, one of the bone destruction mediators in the tissues around the implant, and a decrease in bleeding on probing. CLINICAL SIGNIFICANCE E-cigarette is a potential risk factor for the healing process and the results of implant treatment, similar to cigarettes. Performing clinical research to evaluate the e-cigarette effect on peri‑implantitis in an age and gender-match population is needed.
Collapse
Affiliation(s)
- Zeliha Guney
- Department of Periodontology, Faculty of Dentistry, Ankara Medipol University, Ankara, Turkey
| | - S Merve Altingoz
- Department of Periodontology, Faculty of Dentistry, Lokman Hekim University, Ankara, Turkey
| | - Hande Has
- Graduate School of Health Sciences, Ankara University, Ankara, Turkey
| | - Muhittin A Serdar
- Department of Medical Biochemistry, School of Medicine, Acibadem University, İstanbul, Turkey
| | - Sivge Kurgan
- Department of Periodontology, Faculty of Dentistry, Ankara University, Ankara, Turkey.
| |
Collapse
|
|
15
|
Takekawa T, Moroi A, Gomi K, Takayama A, Yoshizawa K, Ueki K. Correlation Between Acquisition of Dental Implant Stability and Hounsfield Units at Dental Implant Placement. J ORAL IMPLANTOL 2024; 50:24-30. [PMID: 38579113 DOI: 10.1563/aaid-joi-d-22-00233] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 04/07/2024]
Abstract
Alveolar bone quality at the implantation site affects the initial stability of dental implant treatment. However, the relationship between bone quality and osseointegration has yet to be evaluated. Herein, we aimed to investigate the effect of bone quality on dental implant stability in osseointegration formation changes. Patients underwent computed tomography imaging before dental implantation at the posterior. Hounsfield units were measured at the platform, middle, and tip sites. Implant stability was measured using resonance frequency analysis immediately and at 3 months postoperatively, in which the difference in implant stability quotients (ISQ) was defined as the change between primary and secondary fixation. In multiple regression analysis, the dependent variable was the change between the immediate and secondary fixations. We included 81 implants that conformed to the criteria. Primary fixation yielded the following results: R2 = 0.117, F = 2.529, and P = .047. The difference between the maxilla and mandible of the implantation site (P = .02) and the platform-site Hounsfield units (P = .019) were identified as significant factors. The following results were obtained regarding the change between the immediate and secondary fixation: R2 = 0.714, F = 40.964, and P < .001. The difference between diameter (P = .008) and the immediate ISQ (P < .001) were identified as significant factors. Overall, the bone quality of the implantation site affected initial fixation; however, it had limited effect on secondary fixation. Our findings clarified the period where bone quality affects dental implant treatment and is expected to advance dental implant treatment.
Collapse
Affiliation(s)
- Takahiro Takekawa
- Department of Oral and Maxillofacial Surgery, Division of Clinical Medicine, Graduate Faculty of Interdisciplinary Research, University of Yamanashi, Yamanashi, Japan
| | - Akinori Moroi
- Department of Oral and Maxillofacial Surgery, Division of Clinical Medicine, Graduate Faculty of Interdisciplinary Research, University of Yamanashi, Yamanashi, Japan
| | - Karen Gomi
- Department of Oral and Maxillofacial Surgery, Division of Clinical Medicine, Graduate Faculty of Interdisciplinary Research, University of Yamanashi, Yamanashi, Japan
| | - Akihiro Takayama
- Department of Oral and Maxillofacial Surgery, Division of Clinical Medicine, Graduate Faculty of Interdisciplinary Research, University of Yamanashi, Yamanashi, Japan
| | - Kunio Yoshizawa
- Department of Oral and Maxillofacial Surgery, Division of Clinical Medicine, Graduate Faculty of Interdisciplinary Research, University of Yamanashi, Yamanashi, Japan
| | - Koichiro Ueki
- Department of Oral and Maxillofacial Surgery, Division of Clinical Medicine, Graduate Faculty of Interdisciplinary Research, University of Yamanashi, Yamanashi, Japan
| |
Collapse
|
|
16
|
Le Ferrand H, Goh BT, Teoh SH. Nacre-like ceramic composites: Properties, functions and fabrication in the context of dental restorations. Acta Biomater 2024; 173:66-79. [PMID: 38016510 DOI: 10.1016/j.actbio.2023.11.036] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/04/2023] [Revised: 11/02/2023] [Accepted: 11/22/2023] [Indexed: 11/30/2023]
Abstract
Dental restorations are in increasing demand, yet their success rate strongly decreases after 5-10 years post-implantation, attributed in part to mismatching properties with the surrounding buccal environment that causes failures and wear. Among current research to address this issue, biomimetic approaches are promising. Nacre-like ceramic composites are particularly interesting because they combine multiple antagonistic properties making them more resistant to failure in harsh environment than other materials. With the rapid progress in 3D printing producing nacre-like structures has open up new opportunities not yet realised. In this paper, nacre-like composites of various compositions are reviewed in the context of hypothetical biomimetic dental restorations. Their structural, functional and biological properties are compared with those of dentin, enamel, and bone to determine which composition would be the most suitable for each of the 3 mineralized regions found in teeth. The role of complex microstructures and mineral orientations are discussed as well as 3D printing methods that allow the design and fabrication of such complex architectures. Finally, usage of these processes and anticipated prospects for next generation biomimetic dental replacements are discussed to suggest future research directions in this area. STATEMENT OF SIGNIFICANCE: With the current ageing population, dental health is a major issue and current dental restorations still have shortcomings. For the next generation of dental restorations, more biomimetic approaches would be desirable to increase their durability. Among current materials, nacre-like ceramic composites are interesting because they can approach the various structural properties found in the different parts of our teeth. Furthermore, it is also possible to embed self-sensing functionalities to enable monitoring of oral health. Finally, new recent 3D printing technologies now permit the fabrication of complex shapes with local compositions and local microstructures. With this current status of the research, we anticipate new dental restorations designs and highlight the remaining gaps and issues to address.
Collapse
Affiliation(s)
- Hortense Le Ferrand
- School of Mechanical and Aerospace Engineering, 50 Nanyang Avenue, Nanyang Technological University, 639798 Singapore; Singapore 3D Printing Centre, 50 Nanyang Avenue, Nanyang Technological University, 639798 Singapore.
| | - Bee Tin Goh
- National Dental Research Institute Singapore (NDRIS), National Dental Centre Singapore, 5 Second Hospital Avenue, 168938, Singapore
| | - Swee-Hin Teoh
- Centre for Advanced Medical Engineering, School of Materials Science and Engineering, Hunan University, China
| |
Collapse
|
|
17
|
Afrasiabi S, Heidari M, Younespour S, Chiniforush N. Evaluating the effect of mechanical debridement with adjunctive antimicrobial photodynamic therapy in comparison with mechanical debridement alone on the peri-implant parameters in type 2 diabetic mellitus patients with peri-implantitis: a systematic review and meta-analysis. BMC Oral Health 2023; 23:751. [PMID: 37828479 PMCID: PMC10571232 DOI: 10.1186/s12903-023-03337-9] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/10/2023] [Accepted: 08/19/2023] [Indexed: 10/14/2023] Open
Abstract
BACKGROUND Type 2 diabetes mellitus (T2DM) is a major risk factor for localized diseases such as peri-implantitis that may affect ideal implant treatment. This study was aimed to evaluate the effect of mechanical debridement (MD) + antimicrobial photodynamic therapy (a-PDT) in patients with peri-implantitis who have T2DM in terms of bleeding on probing (BOP) and probing depth (PD) as primary outcomes and plaque index (PI) and crestal bone loss (CBL) as secondary outcomes. METHODS Publications compared outcomes between MD + aPDT and MD alone in T2DM patients with peri-implantitis, containing more than 3-month follow-up duration, were involved in the systematic review and meta-analysis. Literature until July 2023 using MEDLINE (through PubMed), Scopus, Cochrane Library, Embase, Web of Science, and Google Scholar were collected. RESULTS Two randomized controlled trials (RCTs, 88 individuals) and one controlled clinical trial (CCT, 67 individuals) with follow-up periods ranged from 3 to 12 months were recruited. All studies used diode laser with wavelengths ranged from 660 to 810 nm. The results demonstrated that the MD + aPDT group showed significant benefits for BOP reduction after 6 months (SMD = -2.15, 95% CI: -3.78 to -0.51, p = 0.01). However, a great amount of heterogeneity was observed (I2 = 91.52%, p < 0.001). Moreover, there was a significant difference between MD + aPDT and MD alone groups in CBL (SMD = -0.69, 95% CI: -1.07 to -0.30, p < 0.001). In addition, homogeneity assumption was satisfied (I2 = 22.49%, p = 0.28). Significant differences in PD and PI reduction were not found except for PI reduction after 3 months (SMD = -0.79, 95% CI: -1.24 to -0.33, p < 0.001. Also, no heterogeneity was observed (I2 = 0.00%, p = 0.47). CONCLUSION Given that high heterogeneity in BOP and PD outcome was found in this systematic review, future long-term CTs with MD + aPDT should be examined to arrive at a firm conclusion.
Collapse
Affiliation(s)
- Shima Afrasiabi
- Laser Research Center of Dentistry, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran
| | - Mohadeseh Heidari
- Dental Implant Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran
| | - Shima Younespour
- Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
| | - Nasim Chiniforush
- Laser Research Center of Dentistry, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
- Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy.
| |
Collapse
|
|
18
|
Tomina DC, Petruțiu ȘA, Crișan B, Leucuța DC, Dinu CM. Influence of Periodontal Status and Prosthetic Treatment on Survival and Success Rates in Implant Therapy: A 5-Year Retrospective Follow-Up Study. J Clin Med 2023; 12:4275. [PMID: 37445310 DOI: 10.3390/jcm12134275] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/01/2023] [Revised: 05/30/2023] [Accepted: 06/24/2023] [Indexed: 07/15/2023] Open
Abstract
The objective of the present study was to evaluate the 5-year outcome of dental implant therapy and assess the survival, success, and biological and technical complications. A periodontal and prosthetic-oriented evaluation was conducted on the variables that can influence the long-term predictability of implant therapy. A total of 615 patients and 1427 dental implants from a private clinic (MedArtis Dent, Cluj-Napoca, Romania) were enrolled in the study. The study was a longitudinal cohort with data collected retrospectively from physical/digital dental records in combination with a cross-sectional clinical/radiological examination. Results showed that periodontal diagnosis at baseline had a significant impact on the marginal bone loss prediction. Data showed that the cylindrical implant with an internal 45° medium taper connection experienced a higher rate of bone resorption compared to the tapered implant with the 5° internal connection. Screw-retained restorations and overdentures showed a statistical decrease in the marginal bone level height when compared to the cemented restorations. Data from our study suggest that not only is there a powerful association between recall visits and the rate of complications in dental implant treatment, but a lack of professional maintenance predicts a higher bone level loss during the 5-year interval.
Collapse
Affiliation(s)
- Darius Cătălin Tomina
- Department of Periodontology, Faculty of Dentistry, University of Medicine and Pharmacy Iuliu Hațieganu, 400012 Cluj-Napoca, Romania
- MedArtis Dent Private Dental Clinic, 400130 Cluj-Napoca, Romania
| | - Ștefan Adrian Petruțiu
- Department of Periodontology, Faculty of Dentistry, University of Medicine and Pharmacy Iuliu Hațieganu, 400012 Cluj-Napoca, Romania
- MedArtis Dent Private Dental Clinic, 400130 Cluj-Napoca, Romania
| | - Bogdan Crișan
- MedArtis Dent Private Dental Clinic, 400130 Cluj-Napoca, Romania
- Department of Maxillofacial Surgery and Implantology, Faculty of Dentistry, University of Medicine and Pharmacy Iuliu Hațieganu, 400012 Cluj-Napoca, Romania
| | - Daniel-Corneliu Leucuța
- Department of Medical Informatics and Biostatistics, Iuliu Hatieganu University of Medicine and Pharmacy, 400349 Cluj-Napoca, Romania
| | - Cristian Mihail Dinu
- MedArtis Dent Private Dental Clinic, 400130 Cluj-Napoca, Romania
- Department of Oral and Cranio-Maxillofacial Surgery, Faculty of Dentistry, University of Medicine and Pharmacy Iuliu Hațieganu, 400012 Cluj-Napoca, Romania
| |
Collapse
|
|
19
|
Kang M, Smanio Neto H, Pelegrine AA, Turssi CP, Clemente-Napimoga JT, Napimoga MH. Survival rate of dental implants installed by postgraduate students attending an implantology program in Brazil: A 52-month retrospective analysis. FRONTIERS IN DENTAL MEDICINE 2023; 4:1170253. [PMID: 39916901 PMCID: PMC11797950 DOI: 10.3389/fdmed.2023.1170253] [Citation(s) in RCA: 2] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/20/2023] [Accepted: 04/05/2023] [Indexed: 02/09/2025] Open
Abstract
Objectives The aim of this study was to assess the survival rate and identify possible risk factors for failure of dental implants placed by postgraduate students in Implantology at a Brazilian Dental School. Materials & methods A retrospective observational study was conducted to evaluate 1,164 dental implants placed by postgraduate students in Implantology at São Leopoldo Mandic Dental School (Brazil) during a 3-year time period (2018-2020). Data collected from the patients' medical charts included the following: implant loss, gender, diabetes, smoking, continuous use of medication, type of implant connection system, implant position (maxilla or mandible), previous bone grafting and type of prosthetic provisioning (temporary prosthesis, immediate prosthesis or permanent prosthesis). The association between all the independent variables and implant loss was run using χ 2 and G tests (α = 5%). The implant survival rate was estimated using Kaplan-Meier curve. Results Gender, diabetes, smoking, continuous use of medication, type of implant connection system, implant position, previous bone grafting and type of prosthetic provisioning showed no statistically significant association with implant loss. Of the 1,164 implants installed, 29 (2.5%) failed. The overall survival rate of dental implants placed by postgraduate students up to 52 months was 90.5% (IC95%: 74.5%-96.7%). Conclusions Implants placed by postgraduate students in Implantology at São Leopoldo Mandic Dental School showed a high survival rate, with gender, diabetes, smoking, continuous use of medication, type of implant connection system, implant position, previous bone grafting and type of prosthetic provisioning not accounting for the risk of implant failure.
Collapse
Affiliation(s)
- Myungjin Kang
- Faculdade São Leopoldo Mandic, Instituto São Leopoldo Mandic, Implantology, Campinas, Brazil
| | - Henrique Smanio Neto
- Faculdade São Leopoldo Mandic, Instituto São Leopoldo Mandic, Implantology, Campinas, Brazil
| | - André Antonio Pelegrine
- Faculdade São Leopoldo Mandic, Instituto São Leopoldo Mandic, Implantology, Campinas, Brazil
| | - Cecilia Pedroso Turssi
- Faculdade São Leopoldo Mandic, Instituto São Leopoldo Mandic, Restorative Dentistry, Campinas, Brazil
| | | | - Marcelo Henrique Napimoga
- Faculdade São Leopoldo Mandic, Instituto São Leopoldo Mandic, Laboratory of Neuro-Immune Interface of Pain Research, Campinas, Brazil
| |
Collapse
|
|
20
|
Sun F, Wei Y, Li S, Nie Y, Wang C, Hu W. Shift in the submucosal microbiome of diseased peri-implant sites after non-surgical mechanical debridement treatment. Front Cell Infect Microbiol 2023; 12:1091938. [PMID: 36726642 PMCID: PMC9884694 DOI: 10.3389/fcimb.2022.1091938] [Citation(s) in RCA: 2] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/07/2022] [Accepted: 12/29/2022] [Indexed: 01/18/2023] Open
Abstract
Objectives The object of this prospective study was to assess the submucosal microbiome shifts in diseased peri-implant sites after non-surgical mechanical debridement therapy. Materials and methods Submucosal plaques were collected from 14 healthy implants and 42 diseased implants before and eight weeks after treatment in this prospective study. Mechanical debridement was performed using titanium curettes, followed by irrigation with 0.2% (w/v) chlorhexidine. Subsequently, 16S rRNA gene sequencing was used to analyze the changes in the submucosal microbiome before and after the non-surgical treatment. Results Clinical parameters and the submucosal microbiome were statistically comparable before and after mechanical debridement. The Alpha diversity decreased significantly after mechanical debridement. However, the microbial richness varied between the post-treatment and healthy groups. In network analysis, the post-treatment increased the complexity of the network compared to pre-treatment. The relative abundances of some pathogenic species, such as Porphyromonas gingivalis, Tannerella forsythia, Peptostreptococcaceae XIG-6 nodatum, Filifactor alocis, Porphyromonas endodontalis, TM7 sp., and Desulfobulbus sp. HMT 041, decreased significantly following the non-surgical treatment. Conclusions Non-surgical treatment for peri-implant diseases using mechanical debridement could provide clinical and microbiological benefits. The microbial community profile tended to shift towards a healthy profile, and submucosal dysbiosis was relieved following mechanical debridement.
Collapse
Affiliation(s)
- Fei Sun
- Department of Periodontology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Peking University School and Hospital of Stomatology, Beijing, China
| | - Yiping Wei
- Department of Periodontology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Peking University School and Hospital of Stomatology, Beijing, China
| | - Siqi Li
- Department of Periodontology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Peking University School and Hospital of Stomatology, Beijing, China
| | - Yong Nie
- Laboratory of Environmental Microbiology, Department of Energy and Resources Engineering, College of Engineering, Peking University, Beijing, China
| | - Cui Wang
- Department of Periodontology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Peking University School and Hospital of Stomatology, Beijing, China,*Correspondence: Wenjie Hu, ; Cui Wang,
| | - Wenjie Hu
- Department of Periodontology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Peking University School and Hospital of Stomatology, Beijing, China,*Correspondence: Wenjie Hu, ; Cui Wang,
| |
Collapse
|
|
21
|
Cai B, Tong Z, Qian Y, Zhu W, Lu Y, Si M. Immediate loaded fixed complete dentures supported by implants in patients with a history of periodontitis: A retrospective cohort study of 2 to 7 years. J Prosthet Dent 2023; 129:125-130. [PMID: 36089545 DOI: 10.1016/j.prosdent.2022.08.006] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.5] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/15/2022] [Revised: 08/03/2022] [Accepted: 08/04/2022] [Indexed: 01/18/2023]
Abstract
STATEMENT OF PROBLEM The outcome of implant-supported fixed complete dentures in edentulous patients with a history of periodontitis is unclear. PURPOSE The purpose of this retrospective clinical study was to assess the clinical outcomes of immediate loaded fixed complete dentures in individuals with a history of periodontitis and to analyze risk factors related to implant failure. MATERIAL AND METHODS A total of 642 implants (146 prostheses) in 119 patients were included. The follow-up period ranged from 2 to 7 years. Implant survival rates, marginal bone loss, mechanical complications, biologic complications, and patient satisfaction were evaluated. The Pearson chi-square test, independent samples t test, and multivariate generalized estimating equation were performed for statistical analysis (α=.05). RESULTS Eleven implants in 9 patients failed, leading to overall survival rates of 98.3% at the implant level and 92.4% at the patient level. The mean ±standard deviation marginal bone loss was 0.62 ±0.86 mm, and marginal bone loss did not differ significantly between axial and tilted implants (P>.05). Mechanical complications were detected in 55 (37.7%) definitive prostheses; biologic complications were detected in 318 (49.5%) implants. Smokers had a significantly lower survival rate than nonsmokers (odds ratio: 6.880, P=.013). Bruxers had a significantly higher incidence of mechanical complications than nonbruxers (P<.001). CONCLUSIONS The immediate loaded fixed complete denture supported by implants is a suitable treatment option for edentulous patients with a history of periodontitis, with high survival implant rates. Smoking is a risk factor for implant failure. Bruxism may increase the incidence of mechanical complications with implant-supported fixed complete dentures, and the overall biologic complication incidence is comparatively high.
Collapse
Affiliation(s)
- Bobo Cai
- Graduate student, Graduate Implantology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Zhejiang, PR China
| | - Zian Tong
- Resident, Department of Oral Implantology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Zhejiang, PR China
| | - Yinjie Qian
- Graduate student, Graduate Implantology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Zhejiang, PR China
| | - Weijun Zhu
- Graduate student, Graduate Implantology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Zhejiang, PR China
| | - Yifan Lu
- Graduate student, Graduate Implantology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Zhejiang, PR China
| | - Misi Si
- Associate Professor, Department of Oral Implantology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Zhejiang, PR China.
| |
Collapse
|
|
22
|
de Tapia B, Bonnin M, Valles C, Mozas C, Herrera D, Sanz M, Nart J. Clinical outcomes and associated factors in the treatment of peri-implant mucositis, combining mechanical debridement and prosthesis modification: A 30-month follow-up prospective case series. J Clin Periodontol 2022; 49:1357-1365. [PMID: 36054620 PMCID: PMC9805102 DOI: 10.1111/jcpe.13711] [Citation(s) in RCA: 6] [Impact Index Per Article: 2.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/15/2022] [Revised: 07/23/2022] [Accepted: 07/27/2022] [Indexed: 01/09/2023]
Abstract
AIM To evaluate the clinical outcome and the associated factors of a treatment protocol for peri-implant mucositis. MATERIALS AND METHODS Patients were evaluated 30 months after a treatment protocol including professional mechanical debridement and modification of the prosthesis contours to improve access for biofilm control. Clinical performance was assessed by means of probing with an electronic pressure-calibrated periodontal probe. The possible impact of implant- and patient-level factors on the changes in peri-implant mucosal inflammation measured with the modified bleeding index (mBI) was evaluated. RESULTS Twenty patients and 61 implants were included in the analysis. At the final visit, 50% of the patients presented bleeding on probing, with a mean mBI of 0.22 (SD 0.27). The adjusted linear regression model showed a significant association between patient's compliance with supportive care visits (p = .006) and mucosal inflammation. Similarly, at the implant level, modified plaque index (p < .001) and an irregular use of interdental brushes (p = .017) had a significant impact on final mBI. CONCLUSIONS Prosthesis modification when needed in association with non-surgical treatment may be an important intervention in the treatment of peri-implant mucositis. Compliance with supportive care visits and the regular use of inter-dental brushes were identified as important factors to achieve mucosal inflammation control.
Collapse
Affiliation(s)
- Beatriz de Tapia
- Department of PeriodontologyUniversitat Internacional de CatalunyaBarcelonaSpain
| | - Maria Bonnin
- Department of PeriodontologyUniversitat Internacional de CatalunyaBarcelonaSpain
| | - Cristina Valles
- Department of PeriodontologyUniversitat Internacional de CatalunyaBarcelonaSpain
| | - Carla Mozas
- Department of PeriodontologyUniversitat Internacional de CatalunyaBarcelonaSpain
| | - David Herrera
- ETEP (Etiology and Therapy of Periodontal and Peri‐implant Diseases) Research GroupUniversity Complutense of MadridMadridSpain
| | - Mariano Sanz
- ETEP (Etiology and Therapy of Periodontal and Peri‐implant Diseases) Research GroupUniversity Complutense of MadridMadridSpain
| | - José Nart
- Department of PeriodontologyUniversitat Internacional de CatalunyaBarcelonaSpain
| |
Collapse
|
|
23
|
Diaz P, Gonzalo E, Villagra LJG, Miegimolle B, Suarez MJ. What is the prevalence of peri-implantitis? A systematic review and meta-analysis. BMC Oral Health 2022; 22:449. [PMID: 36261829 PMCID: PMC9583568 DOI: 10.1186/s12903-022-02493-8] [Citation(s) in RCA: 38] [Impact Index Per Article: 12.7] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/03/2021] [Accepted: 10/04/2022] [Indexed: 11/10/2022] Open
Abstract
Background Peri-implantitis is a usual finding but estimates of its prevalence fluctuate very much. This may be due to the wide variety of disease definitions. This systematic review aims to estimate the overall prevalence of peri-implantitis and the effect of different study designs, function times and use of probing depth on prevalence rate. Methods Following electronic and manual searches of the literature published from January 2005 to December 2021, data were extracted from the studies fitting the study criteria. Fifty-seven articles were included in this study. Results Prevalence of peri-implantitis was 19.53% (95% CI 12.87–26.19) at the patient-level, and 12.53% (95% CI 11.67–13.39) at the implant-level and it remains highly variable even following restriction to the clinical case definition. The use of probing depth like diagnostic criteria affected the prevalence data. Conclusion The results indicate that it remains essential the identification of the diagnostic markers for more accurate disease classification.
Collapse
Affiliation(s)
- Pedro Diaz
- Department of Conservative Dentistry and Bucofacial Prosthesis, Faculty of Odontology, University Complutense of Madrid (UCM), Pza Ramón y Cajal S/N, 28040, Madrid, Spain
| | - Esther Gonzalo
- Department of Conservative Dentistry and Bucofacial Prosthesis, Faculty of Odontology, University Complutense of Madrid (UCM), Pza Ramón y Cajal S/N, 28040, Madrid, Spain.
| | - Luis J Gil Villagra
- Department of Conservative Dentistry and Bucofacial Prosthesis, Faculty of Odontology, University Complutense of Madrid (UCM), Pza Ramón y Cajal S/N, 28040, Madrid, Spain
| | - Barbara Miegimolle
- Department of Conservative Dentistry and Bucofacial Prosthesis, Faculty of Odontology, University Complutense of Madrid (UCM), Pza Ramón y Cajal S/N, 28040, Madrid, Spain
| | - Maria J Suarez
- Department of Conservative Dentistry and Bucofacial Prosthesis, Faculty of Odontology, University Complutense of Madrid (UCM), Pza Ramón y Cajal S/N, 28040, Madrid, Spain
| |
Collapse
|
|
24
|
Abstract
Surface characteristics are an important factor for long-term clinical success of dental implants. Alterations of implant surface characteristics accelerate or improve osseointegration by interacting with the physiology of bone healing. Dental implant surfaces have been traditionally modified at the microlevel. Recently, researchers have actively investigated nano-modifications in dental implants. This review explores implant surface modifications that enhance biological response at the interface between a bone and the implant.
Collapse
Affiliation(s)
- In-Sung Luke Yeo
- Department of Prosthodontics, School of Dentistry and Dental Research Institute, Seoul National University, 101 Daehak-Ro, Jongro-Gu, Seoul 03080, Korea.
| |
Collapse
|
|
25
|
Nandini N, Kunusoth R, Alwala AM, Prakash R, Sampreethi S, Katkuri S. Cylindrical Implant Versus Tapered Implant: A Comparative Study. Cureus 2022; 14:e29675. [DOI: 10.7759/cureus.29675] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 09/28/2022] [Indexed: 11/05/2022] Open
|
|
26
|
Guastaldi FPS, Queiroz TP, Marques DO, Santos ABS, Molon RS, Margonar R, Guastaldi AC. Comparative Evaluation of Implants with Different Surface Treatments Placed in Human Edentulous Mandibles: A 1-Year Prospective Study. J Maxillofac Oral Surg 2022; 21:815-823. [PMID: 36274893 PMCID: PMC9474755 DOI: 10.1007/s12663-021-01600-6] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.7] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/16/2021] [Accepted: 05/28/2021] [Indexed: 10/21/2022] Open
Abstract
The aims of this study were to analyze prospectively and comparatively the peri-implant bone crest levels, bone density, stability and success rate of implants with different surface treatments in human edentulous mandibles. Twenty edentulous patients were selected. Four different implants were placed between the mental foramen. Four groups were evaluated: (1) laser-modified surface (LASER), (2) surface modified by laser with deposition of apatites (LASER + HA), (3) surface modified by double acid etching (ACID, Implacil De Bortoli) and (4) surface modified by sandblasting and acid etching (SLActive®, Straumann). Clinical, radiographic, resonance frequency and tomographic analyses were used. After 4 months, mandibular fixed implant prostheses were installed. Clinical and radiographic analyses were performed at times T0 (immediately after implant placement), T1 (15 days), T2 (30 days), T3 (60 days), T4 (90 days), T5 (120 days), T6 (180 days) and T7 (360 days), post-implant placement. The resonance frequency analysis (RFA) was measured at T0, T4, T6 and T7. The tomographic analysis was performed at T0, T4 and T7. In the radiographic bone density analysis, a statistical difference was found between the SLActive® and LASER + HA groups at T4 (p < 0.05). Statistical differences were observed in RFA at T4 (90 days), between the SLActive® and LASER groups (p < 0.05) and between the SLActive® and LASER + HA groups (p < 0.05). At T6 and T7, statistical differences were found between the SLActive® group and all other implant surfaces (p < 0.01). The experimental surfaces analyzed showed encouraging positive outcomes compared to those of the SLActive® surface. Long-term follow-up should be performed to confirm these results.
Collapse
Affiliation(s)
- Fernando P. S. Guastaldi
- Department of Diagnosis and Surgery, School of Dentistry, São Paulo State University (Unesp), Araraquara, SP Brazil
- Skeletal Biology Research Center, Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Harvard School of Dental Medicine, Thier Research Building, 50 Blossom St, Boston, MA 513A USA
| | - Thallita P. Queiroz
- Department of Health Sciences, University Center of Araraquara (UNIARA), Araraquara, SP Brazil
| | - Daniela O. Marques
- Department of Health Sciences, University Center of Araraquara (UNIARA), Araraquara, SP Brazil
| | - Anne B. S. Santos
- Department of Health Sciences, University Center of Araraquara (UNIARA), Araraquara, SP Brazil
| | - Rafael S. Molon
- Department of Diagnosis and Surgery, School of Dentistry, São Paulo State University (Unesp), Araraquara, SP Brazil
| | - Rogerio Margonar
- Department of Health Sciences, University Center of Araraquara (UNIARA), Araraquara, SP Brazil
| | - Antonio C. Guastaldi
- Department of Physical Chemistry, Institute of Chemistry, São Paulo State University (Unesp), Araraquara, SP Brazil
| |
Collapse
|
|
27
|
Jeon JH, Kim MJ, Yun PY, Jo DW, Kim YK. Randomized clinical trial to evaluate the efficacy and safety of two types of sandblasted with large-grit and acid-etched surface implants with different surface roughness. J Korean Assoc Oral Maxillofac Surg 2022; 48:225-231. [PMID: 36043253 PMCID: PMC9433856 DOI: 10.5125/jkaoms.2022.48.4.225] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/06/2022] [Revised: 08/09/2022] [Accepted: 08/12/2022] [Indexed: 11/16/2022] Open
Abstract
Objectives This study aims to evaluate the efficacy and safety of two types of sandblasted with large-grit and acid-etched (SLA) surface implants with different surface roughness. Patients and Methods This study was conducted based on a clinical record review of 55 patients (mean age, 53.00 years). A total of 80 SLA surface implants was placed. Among the 80 implants, 38 implants placed in 29 subjects had surface roughness (Ra) of 3.09 µm (test group, TG), while the other 42 implants placed in 31 subjects had a surface roughness (Ra) of 2.50 µm (control group, CG). A comparison was made of implant primary/secondary stability; success and survival rates; marginal bone loss; and soft tissue assessment including probing pocket depth (PPD), plaque index (PI), gingival index (GI), and bleeding on probing (BOP) between the groups at 1 year after implant placement. Results Among the implants that were initially registered, 1 from the TG and 4 from the CG dropped out, leaving 37 implants in the TG and 38 implants in the CG to be traced and analyzed. Although 1 TG case showed unstable primary stability, all cases showed stable secondary stability. Success and survival rates at 1 year after implant placement were 100% in both groups. Marginal bone loss was 0.07 mm and 0.00 mm for the TG and CG, respectively, but the difference was not significant. Among the several parameters for evaluation of soft tissue, the TG showed lower PI at 1 year after implant placement (TG=0.00, CG=0.29; P=0.0004), while the remaining categories showed no significant difference between the groups. Conclusion This study shows that the two types of SLA implants with different surface roughness have no difference in efficacy or safety. Therefore, both of the implants can be used safely and with promising outcomes.
Collapse
Affiliation(s)
- Jun-Hyung Jeon
- Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam, Korea
| | - Min-Joong Kim
- Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam, Korea
| | - Pil-Young Yun
- Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam, Korea.,Department of Dentistry and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea
| | - Deuk-Won Jo
- Department of Prosthodontics, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam, Korea
| | - Young-Kyun Kim
- Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam, Korea
| |
Collapse
|
|
28
|
Model-free digital workflow and immediate functional loading of implant-supported monolithic glass-ceramic crowns: A case series. J Dent 2022; 125:104270. [PMID: 36002118 DOI: 10.1016/j.jdent.2022.104270] [Citation(s) in RCA: 4] [Impact Index Per Article: 1.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/10/2021] [Revised: 07/29/2022] [Accepted: 08/20/2022] [Indexed: 11/20/2022] Open
Abstract
OBJECTIVES The aim of this study is to evaluate surgical and prosthetic outcomes of immediate functional loading of implants with glass-ceramic screw-retained single crowns. METHODS A total of 22 implants were placed. Within 24 hours, functional full-contour glass ceramic crowns were delivered to patients. The amount of attached gingiva, Simplified Oral Hygiene Index Score, bleeding on probing, time after extraction, bone type, implant size, soft tissue thickness, primary stability, a general fit of the restoration, occlusal and proximal contacts were recorded. Restorations were followed-up at 1, 3, and 6 months tracking marginal bone loss (MBL), noting changes in occlusal and interproximal contacts, checking other possible complications. RESULTS One implant failed and was removed after 4 weeks (95.5 % survival rate). The rest of the implants and crowns functioned with no complications during the follow-up period of 6 months. Factors such as time after extraction, bone type, implant size, soft tissue thickness, and primary stability recorded in Ncm and implant stability quotient (ISQ) values, were not associated with MBL (p<0.05). Mean MBL was found to be 0.3 mm (standard deviation = 0.42) mesially and 0.4 mm (standard deviation = 0.66) distally. One distal and one mesial proximal contact were found to be missing at the 6-month check-up appointment. CONCLUSIONS Within the limits of this study, fully digital workflow without a 3D printed model could be successfully employed for immediate functional loading with single-unit implant-supported crowns. Further studies are needed to obtain long-term results with a larger sample of patients. CLINICAL SIGNIFICANCE Model-free digital workflow and immediate functional loading of implant-supported monolithic glass-ceramic crown might be viable option to restore a single tooth defect.
Collapse
|
|
29
|
Rahman B, Acharya AB, Siddiqui R, Verron E, Badran Z. Photodynamic Therapy for Peri-Implant Diseases. Antibiotics (Basel) 2022; 11:antibiotics11070918. [PMID: 35884171 PMCID: PMC9311944 DOI: 10.3390/antibiotics11070918] [Citation(s) in RCA: 7] [Impact Index Per Article: 2.3] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/30/2022] [Revised: 06/28/2022] [Accepted: 07/05/2022] [Indexed: 11/16/2022] Open
Abstract
Peri-implant diseases are frequently presented in patients with dental implants. This category of inflammatory infections includes peri-implant mucositis and peri-implantitis that are primarily caused by the oral bacteria that colonize the implant and the supporting soft and hard tissues. Other factors also contribute to the pathogenesis of peri-implant diseases. Based on established microbial etiology, mechanical debridement has been the standard management approach for peri-implant diseases. To enhance the improvement of therapeutic outcomes, adjunctive treatment in the form of antibiotics, probiotics, lasers, etc. have been reported in the literature. Recently, the use of photodynamic therapy (PDT)/antimicrobial photodynamic therapy (aPDT) centered on the premise that a photoactive substance offers benefits in the resolution of peri-implant diseases has gained attention. Herein, the reported role of PDT in peri-implant diseases, as well as existing observations and opinions regarding PDT, are discussed.
Collapse
Affiliation(s)
- Betul Rahman
- Periodontology Unit, Department of Preventive and Restorative Dentistry, College of Dental Medicine, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates; (B.R.); (A.B.A.)
| | - Anirudh Balakrishna Acharya
- Periodontology Unit, Department of Preventive and Restorative Dentistry, College of Dental Medicine, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates; (B.R.); (A.B.A.)
| | - Ruqaiyyah Siddiqui
- College of Arts and Sciences, University City, American University of Sharjah, Sharjah P.O. Box 26666, United Arab Emirates;
| | - Elise Verron
- CNRS, UMR 6230, CEISAM, UFR Sciences et Techniques, Université de Nantes, 2, rue de la Houssinière, BP 92208, CEDEX 3, 44322 Nantes, France;
| | - Zahi Badran
- Periodontology Unit, Department of Preventive and Restorative Dentistry, College of Dental Medicine, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates; (B.R.); (A.B.A.)
- Correspondence:
| |
Collapse
|
|
30
|
Uijlenbroek HJJ, Lin X, Liu T, Zheng Y, Wismeijer D, Liu Y. Bone morphogenetic protein-2 incorporated calcium phosphate graft promotes peri-implant bone defect healing in dogs: A pilot study. Clin Exp Dent Res 2022; 8:1092-1102. [PMID: 35796096 PMCID: PMC9562579 DOI: 10.1002/cre2.613] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/29/2021] [Revised: 06/03/2022] [Accepted: 06/04/2022] [Indexed: 11/12/2022] Open
Abstract
Objectives The evaluation of three different drug delivery modes of bone morphogenetic protein‐2 (BMP‐2) in healing peri‐implant bone defects in beagle dogs. BMP‐2 was incorporated in or onto calcium phosphate (CaP) granules in various ways: (i) directly on the outer layer of granules CaP: as an adsorbed depot; (ii) during the entire precipitation process of CaP: an internally incorporated depot; or (iii) during the biomimetic coating precipitation of BMP‐2 on the surface of CaP granules: as a coating incorporated depot. Material and Methods After extraction of the lower molars and wound healing in 6 male beagle dogs, 36 implants were placed (n = 6 animal per group). Peri‐implant bone defects were induced. The following treatment groups were evaluated: no treatment; air abrasive surface cleaning (SC) using hydroxyapatite; SC and the subsequent filling of the defect with CaP without BMP‐2; SC plus the subsequent filling of the defect with CaP adsorbed BMP‐2; SC plus the subsequent filling of the defect with CaP internally incorporated BMP‐2; SC plus the subsequent filling of the defect with CaP coating incorporated BMP‐2. Histological and histomorphometric analyses were carried out to quantify and compare the changes in bone tissue surrounding the treated implants. Results In Group 1 with no treatment, four implants were lost. Group 5 with the SC and the subsequent filling of the defect with internally incorporated BMP‐2 biomimetically prepared CaP (BioCaP), whereby the BMP‐2 is incorporated in the entire volume of all BioCaP particles, showed overall the best results to regenerate bone around the implants. Conclusion This study concluded that the group treated with SC plus the subsequent filling of the defect with CaP BMP‐2 internally incorporated BMP‐2, whereby BMP‐2 has been incorporated in the entire volume of all CaP particles, showed overall the best results when aiming to regenerate bone around the implants.
Collapse
Affiliation(s)
- Henri J J Uijlenbroek
- Department of Oral Cell Biology, Academic Centre for Dentistry Amsterdam (ACTA), Amsterdam, The Netherlands
| | - Xingnan Lin
- School/Hospital of Stomatology, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China
| | - Tie Liu
- Department of Oral Implantology, the Affiliated Hospital of Stomatology, School of Stomatology, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
| | - Yuanna Zheng
- School/Hospital of Stomatology, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China
| | - Daniel Wismeijer
- Private Practice prof. dr. D. Wismeijer, Ellecom, The Netherlands
| | - Yuelian Liu
- Department of Oral Cell Biology, Academic Centre for Dentistry Amsterdam (ACTA), Amsterdam, The Netherlands
| |
Collapse
|
|
31
|
Stability of Cantilever Fixed Dental Prostheses on Zirconia Implants. MATERIALS 2022; 15:ma15103633. [PMID: 35629659 PMCID: PMC9144678 DOI: 10.3390/ma15103633] [Citation(s) in RCA: 3] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 04/11/2022] [Revised: 05/13/2022] [Accepted: 05/16/2022] [Indexed: 01/13/2023]
Abstract
Background: The objective was to determine the optimal connector size and position within zirconia disks for implant-supported cantilever fixed dental prostheses (ICFDP). Methods: Two-unit ICFDPs (n = 60) were designed for the premolar region with connector sizes of either 9 or 12 mm2 and positioned in the enamel or dentin layer of two different types of zirconia disks. The restorations were milled and cemented onto zirconia implants. After simulated chewing for 1.2 Mio cycles, the fracture load was measured and fractures were analyzed. Results: No fractures of ICFDPs or along the implants were detected after simulated aging. The mean fracture load values were significantly higher for a connector size of 9 mm2 (951 N) compared with 12 mm2 (638 N). For the zirconia material with a higher biaxial flexural strength, the fracture load values were increased from 751 to 838 N, but more implant fractures occurred. The position within the zirconia disk did not influence the fracture load. Conclusions: A connector size of 9 mm2 and a zirconia material with a lower strength should be considered when designing ICFDPS on zirconia implants to reduce the risk of fractures along the intraosseous implant portion.
Collapse
|
|
32
|
Patil C, Agrawal A, Abullais SS, Arora S, Khateeb SU, Fadul A. Elagib M. Effectiveness of Different Chemotherapeutic Agents for Decontamination of Infected Dental Implant Surface: A Systematic Review. Antibiotics (Basel) 2022; 11:593. [PMID: 35625237 PMCID: PMC9137954 DOI: 10.3390/antibiotics11050593] [Citation(s) in RCA: 8] [Impact Index Per Article: 2.7] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/12/2022] [Revised: 04/24/2022] [Accepted: 04/26/2022] [Indexed: 01/27/2023] Open
Abstract
AIM To evaluate the most effective chemotherapeutic agent for decontamination of infected dental implants. MATERIAL AND METHODS A systematic electronic literature search in MEDLINE (PubMed) and Google scholar between January 2010 to December 2021 was carried out by using the PRISMA guidelines. A total of five studies related to chemical decontamination of the dental implant were evaluated. The search strategy was based on the PICOS framework. Randomized controlled trials (RCT's) and cohort studies evaluating the effectiveness of different chemotherapeutic agents for the decontamination of dental implants were included in the study. The outcome variable examined was the most effective chemotherapeutic agent(s) for dental implant surface decontamination after comparing the chemotherapeutic agents used in the qualifying studies. RESULT Out of the basic database of 1564 records, 1380 articles were excluded due to irrelevance, unavailability, and repetition. Furthermore, 134 articles were excluded from 184 studies for various reasons. After further filtration, 13 studies were shortlisted. Two investigators (SSA and SA) appraised the quality of the selected studies using the risk of bias assessment tool. After excluding eight studies, five articles were finally included in the present systematic review. CONCLUSION The data reported for the efficacy of chemotherapeutic agents in cleaning contaminated titanium surfaces are scarce, thus it is not possible to draw a definite conclusion. However, chlorhexidine (CHX) (0.2%, 0.12%), citric acid (40%) and sodium hypochlorite (1%) are the most commonly used chemotherapeutic agents; amongst them, citric acid showed the highest potential for biofilm removal from the contaminated implant surface. All three agents [CHX (0.2%, 0.12%), citric acid (40%), and sodium hypochlorite (1%)] can be recommended as therapeutic agents along with their curbs.
Collapse
Affiliation(s)
- Chayya Patil
- Department of Periodontics, M.G.V’s K.B.H Dental College and Hospital, Nasik 422022, India; (C.P.); (A.A.)
| | - Amit Agrawal
- Department of Periodontics, M.G.V’s K.B.H Dental College and Hospital, Nasik 422022, India; (C.P.); (A.A.)
| | - Shahabe Saquib Abullais
- Department of Periodontics and Community Dental Sciences, King Khalid University, Abha 61421, Saudi Arabia;
| | - Suraj Arora
- Department of Restorative Dental Sciences, King Khalid University, Abha 61421, Saudi Arabia; (S.A.); (S.U.K.)
| | - Shafait Ullah Khateeb
- Department of Restorative Dental Sciences, King Khalid University, Abha 61421, Saudi Arabia; (S.A.); (S.U.K.)
| | - Mohamed Fadul A. Elagib
- Department of Periodontics and Community Dental Sciences, King Khalid University, Abha 61421, Saudi Arabia;
| |
Collapse
|
|
33
|
Passant Connection Screw of Dental Implants: An In Vitro SEM Preliminary Study. BIOMED RESEARCH INTERNATIONAL 2022; 2022:9720488. [PMID: 35496044 PMCID: PMC9050316 DOI: 10.1155/2022/9720488] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 02/10/2022] [Revised: 03/24/2022] [Accepted: 04/05/2022] [Indexed: 11/30/2022]
Abstract
The use of dental implants in oral rehabilitations has become increasingly common, thanks to the safety and predictability of these rehabilitations. Unfortunately, dental implants, being alloplastic devices, are not free from biomechanical complications, especially in the case in which the connections are complex and involve several components. The aim of the study is to highlight what could be surface alterations using different screwing torques, or by repeating the screwing process several times. In this study, 40 passant screws (Osstem®, South Korea Dental Implant Ebony Gold®) were examined under a Zeiss EVO LS 10 scanning electron microscope (SEM), operating with an accelerating voltage of 20 kV. Passant screws were subdivided into 4 groups: 30 Nmm tightening torque; maximum tightening torque; 2 times 30 Nmm tightening torque; no screwing, new ones (control group). There are no significant differences in the surfaces of the passant screws in SEM images, and the 100% of the passant screws is free of defects or fractures. Surely, further studies and investigations will certainly be needed to allow improvement of these devices.
Collapse
|
|
34
|
Meto A, Bardhoshi M, Tragaj E, Halimi E, Xhajanka E, Cervino G, D'Amico C, Fiorillo L, Meto A. The use of monophasic implants as an alternative of implant-prosthetic rehabilitation in the posterior maxilla with no sinus lift. Minerva Dent Oral Sci 2022; 71:25-30. [PMID: 35289541 DOI: 10.23736/s2724-6329.21.04544-7] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/08/2022]
Abstract
BACKGROUND Over the years, numerous studies and advanced technologies about dental implants have been evolved from the traditional two-stage procedure to immediate loading. Implants located in the posterior maxillary region allow to achieve an appropriate prosthetic support. The aim of this work was to solve the atrophied posterior maxilla, through monophasic implants with flapless technique and intraoral electro-welding. METHODS In this study were enrolled 120 patients between 20 and 68 years old (mean age of 34.2 years), where females predominate with 53.1% compared to 46.9% males. The patients were presented at the Oral Surgery Clinic of the Aldent University (Tirana, Albania), for a period 2009-2019. Briefly, 310 monophasic implants were placed, TRAMONTE type (Milan, Italy), to the posterior maxilla thus avoiding the sinus, with dense and wide threads, of different lengths and widths. The surgical technique was minimally invasive, flapless one. Data were expressed as mean + standard error (SEM) of all the radiographic outcomes obtained; and as statistical analysis was used the Student's t-test. P<0.5 and P<0.05, were considered significant. RESULTS A part of the patients were hypertensive and type 2 diabetic, then a negligible part were smokers, also a lack of oral hygiene was observed in 40% of cases. After 5 years of observation, it appeared that 95.9% of the implants were successful. Furthermore, the mesial and distal bone loss during the first three years was 0.1 mm, while after 5 years no continuation of bone loss was observed. CONCLUSIONS The application of monophasic implants must be performed according to approved protocols, considering the conditions of the posterior maxillary region, obtaining in this way a safe dental implantation.
Collapse
Affiliation(s)
- Agron Meto
- Department of Implantology, Faculty of Dentistry, University of Aldent, Tirana, Albania
| | - Merita Bardhoshi
- Department of Oral and Maxillofacial Surgery, Faculty of Dental Medicine, University of Medicine, Tirana, Albania
| | - Emiljano Tragaj
- Department of Implantology, Faculty of Dentistry, University of Aldent, Tirana, Albania
| | - Estela Halimi
- Department of Implantology, Faculty of Dentistry, University of Aldent, Tirana, Albania
| | - Edit Xhajanka
- Department of Prosthodontics, Faculty of Dental Medicine, University of Medicine, Tirana, Albania
| | - Gabriele Cervino
- Department of Biomedical and Dental Sciences, Morphological and Functional Images, University of Messina, Messina, Italy
| | - Cesare D'Amico
- Department of Biomedical and Dental Sciences, Morphological and Functional Images, University of Messina, Messina, Italy
| | - Luca Fiorillo
- Department of Biomedical and Dental Sciences, Morphological and Functional Images, University of Messina, Messina, Italy - .,Multidisciplinary Department of Medical-Surgical and Odontostomatological Specialties, Luigi Vanvitelli University of Campania, Naples, Italy
| | - Aida Meto
- Department of Dental Therapy, Faculty of Dental Medicine, University of Medicine, Tirana, Albania
| |
Collapse
|
|
35
|
Lähteenmäki H, Pätilä T, Räisänen IT, Kankuri E, Tervahartiala T, Sorsa T. Repeated Home-Applied Dual-Light Antibacterial Photodynamic Therapy Can Reduce Plaque Burden, Inflammation, and aMMP-8 in Peri-Implant Disease—A Pilot Study. Curr Issues Mol Biol 2022; 44:1273-1283. [PMID: 35723308 PMCID: PMC8947626 DOI: 10.3390/cimb44030085] [Citation(s) in RCA: 3] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/14/2022] [Revised: 03/03/2022] [Accepted: 03/03/2022] [Indexed: 12/11/2022] Open
Abstract
Until now, in clinical dentistry, antibacterial photodynamic therapy (aPDT) has been restricted to in-office treatments, which hampers repeated applications. This pilot study tested the benefit of a commercially available Lumoral® device designed for regular periodontal dual-light aPDT treatment at home. Seven patients with peri-implant disease applied dual-light aPDT daily in addition to their normal dental hygiene for four weeks. A single Lumoral® treatment includes an indocyanine green mouth rinse followed by 40 J/cm2 radiant exposure to a combination of 810 nm and 405 nm light. A point-of-care analysis of active-matrix metalloproteinase (aMMP-8), visible plaque index (VPI), bleeding on probing (BOP), and peri-implant pocket depth (PPD) measurements was performed on day 0, day 15, and day 30. Reductions in aMMP-8 (p = 0.047), VPI (p = 0.03), and BOP (p = 0.03) were observed, and PPD was measured as being 1 mm lower in the implant (p = ns). These results suggest a benefit of regular application of dual-light aPDT in peri-implantitis. Frequently repeated application can be a promising approach to diminishing the microbial burden and to lowering the tissue destructive proteolytic and inflammatory load around dental implants. Further studies in larger populations are warranted to show the long-term benefits.
Collapse
Affiliation(s)
- Hanna Lähteenmäki
- Department of Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, 00280 Helsinki, Finland; (I.T.R.); (T.T.); (T.S.)
- Correspondence: ; Tel.: +358-50-3248433
| | - Tommi Pätilä
- Department of Pediatric Heart Surgery and Organ Transplantation, New Children’s Hospital, Helsinki University, 00100 Helsinki, Finland;
| | - Ismo T. Räisänen
- Department of Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, 00280 Helsinki, Finland; (I.T.R.); (T.T.); (T.S.)
| | - Esko Kankuri
- Department of Pharmacology, Helsinki University, 00100 Helsinki, Finland;
| | - Taina Tervahartiala
- Department of Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, 00280 Helsinki, Finland; (I.T.R.); (T.T.); (T.S.)
| | - Timo Sorsa
- Department of Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, 00280 Helsinki, Finland; (I.T.R.); (T.T.); (T.S.)
- Division of Periodontology, Department of Dental Medicine, Karolinska Institutet, 141 52 Huddinge, Sweden
| |
Collapse
|
|
36
|
Onclin P, Slot W, Vissink A, Raghoebar GM, Meijer HJA. Incidence of peri-implant mucositis and peri-implantitis in patients with a maxillary overdenture: A sub-analysis of two prospective studies with a 10-year follow-up period. Clin Implant Dent Relat Res 2022; 24:188-195. [PMID: 35137509 PMCID: PMC9304206 DOI: 10.1111/cid.13071] [Citation(s) in RCA: 10] [Impact Index Per Article: 3.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/17/2021] [Revised: 10/07/2021] [Accepted: 01/23/2022] [Indexed: 02/05/2023]
Abstract
Background Though studies on maxillary overdentures show satisfying results on implant survival, patient‐related outcomes and prosthetic complications, the epidemiology of peri‐implant diseases in this specific group of patients has hardly been reported. While the general patient‐level prevalence of peri‐implant mucositis and peri‐implantitis are estimated at ~45% and ~20%, respectively, the risk of developing these diseases within a specific period is less clear. To fully appreciate the epidemiology of peri‐implant diseases, more long‐term data on incidence of peri‐implant diseases are needed. Purpose The purpose of this sub‐analysis of two prospective studies was to assess the incidence of peri‐implant mucositis and peri‐implantitis in fully edentulous patients with implant‐retained maxillary overdentures during a 10‐year follow‐up period. Materials and Methods One hundred and sixteen patients treated with implant‐supported maxillary overdentures were available from two clinical trials. Data on biological complications, clinical and radiographical parameters were collected for 106 patients at 5‐year, for 82 patients at 10‐year follow‐up. The incidence was calculated following the consensus of the 2017 World Workshop on the Classification of Periodontal and Peri‐Implant Diseases and Conditions. Extent and severity then were calculated to enable an appropriate epidemiological description of peri‐implantitis. Results The patient‐level incidence of peri‐implant mucositis was 37.7% after 5 years and 64.6% after 10 years whereas the patient‐level incidence of peri‐implantitis was 10.4% after 5 years and 19.5% after 10 years. After 10 years, the extent of peri‐implant mucositis and peri‐implantitis is 52.8% and 43.8%, respectively. In terms of severity, 26.5% of all affected implants suffered from >3 mm bone loss and 17.6% of all affected implants was lost. Conclusion Three of five fully edentulous patients with implant‐supported maxillary overdentures experience peri‐implant mucositis after 10 years. Peri‐implantitis occurs in one of five patients after 10 years. In spite of these incidence rates, implant survival remains high.
Collapse
Affiliation(s)
- Pieter Onclin
- Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
| | - Wim Slot
- Department of Implant Dentistry, Dental School, University of Groningen, University Medical Center, Groningen, The Netherlands
| | - Arjan Vissink
- Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
| | - Gerry M Raghoebar
- Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
| | - Henny J A Meijer
- Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.,Department of Implant Dentistry, Dental School, University of Groningen, University Medical Center, Groningen, The Netherlands
| |
Collapse
|
|
37
|
AlJasser R, Zahid M, AlSarhan M, AlOtaibi D, AlOraini S. The effect of conventional versus electronic cigarette use on treatment outcomes of peri-implant disease. BMC Oral Health 2021; 21:480. [PMID: 34579704 PMCID: PMC8477469 DOI: 10.1186/s12903-021-01784-w] [Citation(s) in RCA: 4] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/09/2021] [Accepted: 08/25/2021] [Indexed: 11/10/2022] Open
Abstract
Aim To compare changes in clinical periodontal parameters (gingival consistency, colour, BOP, PI, PD) and changes of salivary inflammatory biomarkers (IL-1 β, IL-6, MMP-8, TNF- α and TIMP-1 between conventional, electronic cigarette smokers and non-smokers after peri-implant treatment. Methods Study participants were grouped into three groups (i) Conventional cigarette smokers (ii) Electronic cigarette smokers and (iii) non-smokers respectively. A total of 60 adult patients aged (40–56 years) with 60 implants with active per-impantitis was included.Clinical and Biological parameters were evaluated before surgical treatment at baseline, one, six and twelve month post treatment. Pearson’s chi-square test was used to compare the distribution of the categorical while Two-way repeated analysis of variance was used to compare the mean values of quantitative outcome variables among all study groups across the 4 time points. Results A total of 60 subjects (60 implants) were selected and classified into three groups as per their smoking method 20 participants in each group with one single targeted implant diagnosis with active peri-implantitis. The gingival colour, the change was statistically significant at one year of post treatment.The gingival consistency distribution across the three groups is not statistically significant at baseline, but it is statistically significant at one-month (p = 0.001), six months (p = 0.029) and at the completion of one-year (p = 0.018) post treatment. The plaque index of 100% of non-smokers had changed to ‘0’ and 35% change in cigarettes and 30% change in electronic smokers which is statistically significant (p = 0.016).The prevalence of BOP was observed in the three groups as 72%, 76.5% and 88.9% at baseline. The mean values of PD have shown statistically significant change across the three groups over the four-time intervals of observation (p = 0.024). The comparison of mean values of IL-1 β, IL-6 and TIMP-1 has shown statistically significant change across the three groups over the four intervals of observation (p < 0.0001). Conclusions Electronic cigarette smoking was found to be most prevalent risk indicator for peri-implantitis. Compromised response of peri-implantitis treatment both clinically and biologically was found more among electronic cigarette smokers when compared to conventional cigarette smokers and non-smokers. Trial registration: This case-control study was conducted at King Saud University’s Dental College, Riyadh, Saudi Arabia, in accordance with “Helsinki Declaration of Human Studies” and approved by the Institutional Review Board (Reference no: 87563).
Collapse
Affiliation(s)
- Reham AlJasser
- Department of Periodontics and Community Dentistry, Dental College, King Saud University, PO Box 60169, Riyadh, 11545, Saudi Arabia.
| | - Mohammed Zahid
- Saudi Board of Periodontics Resident, Ministry of Health, Riyadh, Saudi Arabia
| | - Mohammed AlSarhan
- Department of Periodontics and Community Dentistry, Dental College, King Saud University, PO Box 60169, Riyadh, 11545, Saudi Arabia
| | - Dalal AlOtaibi
- Department of Periodontics and Community Dentistry, Dental College, King Saud University, PO Box 60169, Riyadh, 11545, Saudi Arabia
| | - Saleh AlOraini
- Department of Periodontics and Community Dentistry, Dental College, King Saud University, PO Box 60169, Riyadh, 11545, Saudi Arabia
| |
Collapse
|
|
38
|
Wang Y, Yu Z, Li K, Hu J. Study on the effect of surface characteristics of short-pulse laser patterned titanium alloy on cell proliferation and osteogenic differentiation. MATERIALS SCIENCE & ENGINEERING. C, MATERIALS FOR BIOLOGICAL APPLICATIONS 2021; 128:112349. [PMID: 34474898 DOI: 10.1016/j.msec.2021.112349] [Citation(s) in RCA: 4] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Subscribe] [Scholar Register] [Received: 03/19/2021] [Revised: 06/23/2021] [Accepted: 07/26/2021] [Indexed: 01/14/2023]
Abstract
Concise, low-cost preparation of titanium alloy implants with high cell proliferation and osteogenic differentiation is urgently needed. Nanosecond laser ablation of titanium alloy has the advantages of short processing time, less pollution, and non-contact. In this research, we adopt a nanosecond UV laser to process the closed groove and cross groove titanium alloys with length to width ratio of 1:1, 2.5:1, 4:1, and 6:1. The surface morphology, surface roughness, phase, element distribution, surface chemistry, and wettability were characterized. The effect of the patterned surface's properties on the adhesion, proliferation, and osteogenic differentiation of stem cells was studied. The results show the laser-ablated lattice structure's surface energy can increase rapidly in the natural environment. The cell adhesion of stem cells on a lattice structure with low roughness and high surface energy is optimal. The element concentration at the ablated edges is higher than at the bottom under Marangoni and surface tension. Stem cells preferentially adhere to the ablated edges with high roughness, element concentration, and hardness. Cell differentiation is chiefly affected by patterning structure. On the surface of the boss structure with a length to width ratio of 2.5:1, the proportion of cell length to diameter is about 2.5, and the cell area is greater. The osteogenic differentiation of cells is the highest on the surface.
Collapse
Affiliation(s)
- Yifei Wang
- College of Mechanical Engineering, Donghua University, Shanghai 201620, China
| | - Zhou Yu
- Institute of Artificial Intelligence, Donghua University, Shanghai 201620, China
| | - Kangmei Li
- Shanghai Collaborative Innovation Center for High Performance Fiber composites, Donghua University, Shanghai 201620, China; State Key Lab of Digital Manufacturing Equipment & Technology, Wuhan 430074, China
| | - Jun Hu
- Institute of Artificial Intelligence, Donghua University, Shanghai 201620, China.
| |
Collapse
|
|
39
|
Lv XL, Qian SJ, Qiao SC, Gu YX, Lai HC, Shi JY. Clinical, radiographic, and immunological evaluation of angulated screw-retained and cemented single-implant crowns in the esthetic region: A 1-year randomized controlled clinical trial. Clin Implant Dent Relat Res 2021; 23:692-702. [PMID: 34390601 DOI: 10.1111/cid.13035] [Citation(s) in RCA: 7] [Impact Index Per Article: 1.8] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/13/2020] [Revised: 05/08/2021] [Accepted: 07/19/2021] [Indexed: 12/17/2022]
Abstract
BACKGROUND Screw-retained implant crowns are considered more biologically compatible than cemented crowns due to the absence of excess cement. However, traditional screw-retained implant crowns are not viable when the access hole of the screw channel would need to be located in an esthetic area, which would compromise the esthetic outcome of the treatment. PURPOSE To evaluate the clinical, radiographic, and immunological outcomes of angulated screw-retained and cemented single-implant crowns in the esthetic region. MATERIALS AND METHODS The study was a single-center, open-label, randomized controlled clinical trial. Eligible patients were randomly placed in two groups: angulated screw-retained group (AG) and cemented group (CG). Implant survival rate, bleeding on probing rate (BOP%), probing depth (PD), modified plaque index (mPI), marginal bone loss (MBL), concentrations of pro-inflammatory cytokines (TNF-α, IL-6) in peri-implant crevicular fluid (PICF), mechanical complications, and pink esthetic score/white esthetic score (PES/WES) were evaluated. RESULTS Fifty-six patients (AG: 29, CG: 27) attended the 1-year examination. The drop-out rate was 6.67%. No implant failure was found in both groups during the observation period. BOP% was significantly lower in the AG than that in the CG (mean, 21.84% ± 19.97% vs. 37.04% ± 26.28%, p = 0.018). The concentration of TNF-α in PICF was significantly higher in the AG than that in the CG (median, 13.54 vs. 4.62, p = 0.019). No significant difference of PD, mPI, MBL, IL-6, or mechanical complication rates was found between the two groups. Mean scores for PES/WES were 21.71 and 21.64 in the AG and CG, respectively. CONCLUSION Based on the present results, both treatment options showed acceptable clinical outcomes in the short term. Angulated screw-retained crowns might benefit the peri-implant soft tissue. However, studies with long-term follow-up are needed to confirm whether the higher concentration of TNF-α will compromise the long-term outcomes of treatment.
Collapse
Affiliation(s)
- Xiao-Lei Lv
- Department of Oral and Maxillo-facial Implantology, Shanghai Key Laboratory of Stomatology, National Clinical Research Center for Stomatology, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China
| | - Shu-Jiao Qian
- Department of Oral and Maxillo-facial Implantology, Shanghai Key Laboratory of Stomatology, National Clinical Research Center for Stomatology, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China
| | - Shi-Chong Qiao
- Department of Oral and Maxillo-facial Implantology, Shanghai Key Laboratory of Stomatology, National Clinical Research Center for Stomatology, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China
| | - Ying-Xin Gu
- Department of Oral and Maxillo-facial Implantology, Shanghai Key Laboratory of Stomatology, National Clinical Research Center for Stomatology, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China
| | - Hong-Chang Lai
- Department of Oral and Maxillo-facial Implantology, Shanghai Key Laboratory of Stomatology, National Clinical Research Center for Stomatology, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China
| | - Jun-Yu Shi
- Department of Oral and Maxillo-facial Implantology, Shanghai Key Laboratory of Stomatology, National Clinical Research Center for Stomatology, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China
| |
Collapse
|
|
40
|
Nature-Inspired Nanoflower Structures on Titanium Surface via Alkali Treatment for Biomedical Applications. JOURNAL OF BIOMIMETICS BIOMATERIALS AND BIOMEDICAL ENGINEERING 2021. [DOI: 10.4028/www.scientific.net/jbbbe.52.20] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/21/2022]
Abstract
Titanium based metallic biomaterials for orthopedic implant applications are often associated with biocompatibility problems which can be ameliorated via proper surface modification strategies. Improving the hydrophilic nature of the titanium surface offers an effective strategy to sort out such limitations by intensifying the cellular activity. Development of titania as well as titanate layers on the titanium surface via alkali treatment represents an effective strategy to improve the hydrophilicity of native titanium surface. Inspired from nature, in the present work, we report the formation of three-dimensional (3D) hierarchical nanoflowers resembling Gomphrena globosa flowers developed on commercially pure titanium (cp-Ti) surface via a facile alkali treatment technique. X-ray diffraction studies evidenced anatase and rutile phases of TiO2 confirming the development of titania on the surface. In addition to the TiO2 phase, presence of titanate (Na2Ti3O7) has also been observed as alkali treatment was conducted in NaOH solution. The hydrophilicity of the Ti surface has been enhanced after the alkali treatment as evidenced from wettability studies using static contact angle measurements. This increase in hydrophilicity is due to the enrichment of the surface by TiO2 and titanate and increased roughness of nanoflower surface based on classical Wenzel law. In addition, the alkali-treated surface demonstrated an increased polar surface energy beneficial for biocompatible surfaces.
Collapse
|
|
41
|
Accuracy of Dental Implant Placement by a Novel In-House Model-Free and Zero-Setup Fully Guided Surgical Template Made of a Light-Cured Composite Resin (VARO Guide ®): A Comparative In Vitro Study. MATERIALS 2021; 14:ma14144023. [PMID: 34300944 PMCID: PMC8304558 DOI: 10.3390/ma14144023] [Citation(s) in RCA: 5] [Impact Index Per Article: 1.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 06/22/2021] [Revised: 07/15/2021] [Accepted: 07/17/2021] [Indexed: 11/16/2022]
Abstract
BACKGROUND This in vitro study mainly aimed to compare VARO Guide® to the surgical guide fabricated by CAD/CAM (NAVI Guide®) in terms of accuracy and efficacy of the implant surgery held in the dentiform model. METHODS Twenty surgeons, 10 dentists in the beginner group and 10 dentists in the expert group, participated in the study. Each surgeon conducted fully guided surgery in dentiform models twice, once with VARO Guide® (VG surgery) and the other time with a conventional type of templates, NAVI Guide® (NG surgery). Based on the superimposition of presurgical and postsurgical STL files, the positional deviations between the virtually planned and actually placed implants and the time spent on presurgical preparation and surgical procedures were estimated and compared. RESULTS All dimensional deviations were similar between the two groups (p > 0.05), and there was no significant difference between the expert and beginner groups regardless of the guide system. The total procedure time (mean (median)) of the VG surgery (26.33 (28.58) min) was significantly shorter than that of the NG surgery (378.83 (379.35) min; p < 0.05). While the time spent only for the fully guided implant surgery (from the start of the surgical guide sitting onto the dentiform model to the final installation of the implant fixture) was comparable (p > 0.05), the presurgical preparation time spent on virtual implant planning and surgical guide fabrication in the VG surgery (19.63 (20.93) min) was significantly shorter compared to the NG surgery (372.93 (372.95) min; p < 0.05). CONCLUSIONS Regardless of experience, both VG and NG surgery showed reliable positional accuracy; however, the total procedure time and the preparation time were much shorter in the VG surgery compared to the NG surgery.
Collapse
|
|
42
|
Risk Indicators Affecting the Survival of the Mandibular First Molar Adjacent to an Implant at the Mandibular Second Molar Site: A Retrospective Study. J Clin Med 2021; 10:jcm10122543. [PMID: 34201316 PMCID: PMC8227410 DOI: 10.3390/jcm10122543] [Citation(s) in RCA: 3] [Impact Index Per Article: 0.8] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/04/2021] [Revised: 05/29/2021] [Accepted: 06/04/2021] [Indexed: 11/22/2022] Open
Abstract
This study aimed to compare the survival of mandibular first molars (MnM1s) adjacent to implants placed in mandibular second molar sites (ImM2s) with MnM1s adjacent to mandibular second molars (MnM2s) and to investigate risk indicators affecting the survival of MnM1s adjacent to ImM2s. A total of 144 patients who had MnM1s adjacent to ImM2s and MnM1s adjacent to MnM2s on the contralateral side were included in this study. Clinical variables and radiographic bone levels were evaluated. The survival of MnM1s adjacent to ImM2s or MnM2s was evaluated using a Kaplan–Meier analysis and Cox proportional hazards model. The 5-year cumulative survival rates of MnM1s adjacent to ImM2s and MnM2s were 85% and 95%, respectively. MnM1s adjacent to ImM2s of the internal implant-abutment connection type had higher multivariate hazard ratios (HR) for loss. MnM1s that had antagonists with implant-supported prostheses also had higher HR for loss. The multivariate HR for the loss of MnM1s adjacent to ImM2s with peri-implant mucositis was 3.74 times higher than MnM1s adjacent to healthy ImM2s. This study demonstrated several risk indicators affecting the survival of MnM1s adjacent to ImM2s. It is suggested that supportive periodontal and peri-implant therapy combined with meticulous occlusal adjustment can prolong the survival of MnM1s and ImM2s.
Collapse
|
|
43
|
Rohr N, Balmer M, Jung RE, Kohal RJ, Spies BC, Hämmerle CHF, Fischer J. Influence of zirconia implant surface topography on first bone implant contact within a prospective cohort study. Clin Implant Dent Relat Res 2021; 23:593-599. [PMID: 34047019 DOI: 10.1111/cid.13013] [Citation(s) in RCA: 3] [Impact Index Per Article: 0.8] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/19/2021] [Revised: 04/12/2021] [Accepted: 04/29/2021] [Indexed: 01/29/2023]
Abstract
BACKGROUND Although 5-year clinical data exist for different zirconia implants, no analysis has yet been performed focusing on how the surface topography of the implant affects clinical parameters. PURPOSE To analyze the influence of zirconia implant topography on first bone implant contact (fBIC). MATERIALS AND METHODS In a prospective two-center cohort investigation 63 zirconia implants were evaluated at implant placement, prosthetic delivery, 1, 3, and 5 years. The distance (DIB) between implant shoulder and fBIC was measured at each time point in periapical radiographs at mesial and distal sites. Two-way ANOVA/Bonferroni was used to analyze the effects of time and center (α < 0.05). RESULTS Between the centers, the mean DIB varied significantly at implant placement (Freiburg [FR]: 1.4 ± 0.6 mm; Zurich [ZH]: 0.8 ± 0.5 mm). Thereafter, no statistically significant difference in DIB was observed, neither between centers nor between time points (prosthetic delivery: FR: 1.9 ± 0.6 mm, ZH: 1.7 ± 0.8 mm; 1 year: FR: 1.8 ± 0.6 mm, ZH: 1.6 ± 0.8 mm; 3 years: FR: 1.9 ± 0.8 mm, ZH: 1.7 ± 0.8 mm; 5 years: FR: 1.9 ± 0.8 mm, ZH 1.8 ± 0.6 mm). The overall mean DIB at prosthetic delivery to 5 years of both centers (1.8 ± 0.7 mm) is located within the transition zone between the smooth neck and the moderately rough intraosseous part (1.6-2.0 mm from the implant shoulder). However, individual DIB values are ranging from 0.1 to 4.2 mm overlapping the transition zone. CONCLUSIONS The standard deviation of the DIB indicates that the fBIC establishes on moderately rough and smooth surfaces. Consequently, soft tissue adapts to both topographies as well.
Collapse
Affiliation(s)
- Nadja Rohr
- Biomaterials and Technology, Department of Reconstructive Dentistry, University Center for Dental Medicine Basel, University of Basel, Basel, Switzerland
| | - Marc Balmer
- Clinic of Reconstructive Dentistry, Center of Dental Medicine, University of Zurich, Zurich, Switzerland
| | - Ronald E Jung
- Clinic of Reconstructive Dentistry, Center of Dental Medicine, University of Zurich, Zurich, Switzerland
| | - Ralf J Kohal
- Department of Prosthetic Dentistry, Center for Dental Medicine, Faculty of Medicine, Medical Center-University of Freiburg, Freiburg, Germany
| | - Benedikt C Spies
- Department of Prosthetic Dentistry, Center for Dental Medicine, Faculty of Medicine, Medical Center-University of Freiburg, Freiburg, Germany
| | - Christoph H F Hämmerle
- Clinic of Reconstructive Dentistry, Center of Dental Medicine, University of Zurich, Zurich, Switzerland
| | - Jens Fischer
- Biomaterials and Technology, Department of Reconstructive Dentistry, University Center for Dental Medicine Basel, University of Basel, Basel, Switzerland
| |
Collapse
|
|
44
|
AlJasser RN, AlSarhan MA, Alotaibi DH, AlOraini S, Ansari AS, Habib SR, Zafar MS. Analysis of Prosthetic Factors Affecting Peri-Implant Health: An in vivo Retrospective Study. J Multidiscip Healthc 2021; 14:1183-1191. [PMID: 34079276 PMCID: PMC8164962 DOI: 10.2147/jmdh.s312926] [Citation(s) in RCA: 4] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/26/2021] [Accepted: 05/04/2021] [Indexed: 12/31/2022] Open
Abstract
Objective To investigate and compare the various restorative and prosthetic parameters affecting peri-implant tissues’ health following dental implant placement and functional loading. Methods A total of 484 dental implants (length>6mm, non-turned, 2–3 piece, titanium – Straumann) were evaluated for patients (male=271; female=213). Study variables such as patient’s age, gender, implant restoration/crown type, crown retention, and implant crown status were assessed against various periodontal parameters (periodontal pocket depth (PPD), plaque index (PI), bleeding on probing (BOP), gingival color, and crestal bone level). All the data were analyzed using the SPSS software. Results Out of all the investigated dental implants, 201 (42%) of the implants investigated presented with BOP > one-site of the peri-implant mucosa (peri-implant mucositis), 115 (23.76%) presented with peri-implant marginal bone loss. PPD value was significantly lower in good crown status (p<0.0001). Majority of the patients with good crown status had no plaque accumulation based on the PI scores (52.7%). Only 35% of the patients whose crown status was good were having BOP when compared with 65% who did not have any BOP recorded. Gingival color (pale pink and red) showed statistically significant association with crown type (porcelain fused to metal v/s all ceramic) (p=0.005). Most of patients with crown status good had no change in their radiographic findings (94%) compared to only 6% who had implant threads exposed (p<0.0001). Conclusion Optimal design of Implant prosthetic factors are vital for avoiding the development of peri-implant mucositis/peri-implantitis and must be considered during treatment planning while restoring dental implants.
Collapse
Affiliation(s)
- Reham N AlJasser
- Department of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh, Saudi Arabia
| | - Mohammed A AlSarhan
- Department of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh, Saudi Arabia
| | - Dalal H Alotaibi
- Department of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh, Saudi Arabia
| | - Saleh AlOraini
- Department of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh, Saudi Arabia
| | - Abdul Sadekh Ansari
- Dental University Hospital, King Saud University Medical City, Riyadh, Saudi Arabia
| | - Syed Rashid Habib
- Department of Prosthetic Dental Sciences, College of Dentistry, King Saud University, Riyadh, Saudi Arabia
| | - Muhammad Sohail Zafar
- Department of Restorative Dentistry, College of Dentistry, Taibah University, Al Madinah, Al Munawwarah, 41311, Saudi Arabia.,Department of Dental Materials, Islamic International Dental College, Riphah International University, Islamabad, 44000, Pakistan
| |
Collapse
|
|
45
|
Leisner L, Kronsteiner D, Rammelsberg P. Effect of previous implant failure on the prognosis of subsequent implants: A retrospective study. Clin Oral Implants Res 2021; 32:863-870. [PMID: 33949012 DOI: 10.1111/clr.13762] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.5] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/19/2021] [Revised: 03/11/2021] [Accepted: 04/06/2021] [Indexed: 02/02/2023]
Abstract
OBJECTIVES To compare the long-term survival of dental implants placed in patients with and without a history of implant failure. MATERIAL AND METHODS Within a retrospective analysis, an experimental group was selected consisting of 59 patients with 137 implants placed after previous failure. The control group included 1,072 patients with 2,664 implants without previous failure. Kaplan-Meier curves were used to describe the group-specific long-term implant survival. Mixed-effects Cox regression models were applied to examine the effects of patient- and site-specific risk factors. To take multiple implants into account, a random intercept model was applied. RESULTS During the observation period of up to 15 years, 11 implants (8%) failed in the experimental group and 74 implants (2.5%) in the control group (p < .001). Five-year cumulative survival was 96.8% (95% CI 0.96-0.98) in the control group and 91.5% (95% CI 0.86-0.97) in the experimental group. The variables group assignment and simultaneous augmentation had a significant effect on survival, but this effect was lost in the random intercept model. The effect of implant location remained, whereby the risk of failure was five times lower for mandible implants, irrespective of group (p = .013; 95% CI 0.103-0.767; HR: 0.281). CONCLUSIONS Long-term implant survival was lower in the experimental group than in the control group. The effect of previous failure was negligible. However, a patient-specific "clustering effect" was observed. Irrespective of previous implant failure, the risk of long-term failure is two times higher for maxillary implants than for mandibular implants.
Collapse
Affiliation(s)
- Laura Leisner
- Department of Prosthodontics, Heidelberg University Hospital, University of Heidelberg, Heidelberg, Germany
| | - Dorothea Kronsteiner
- Institute of Medical Biometry and Informatics, Heidelberg University Hospital, University of Heidelberg, Heidelberg, Germany
| | - Peter Rammelsberg
- Department of Prosthodontics, Heidelberg University Hospital, University of Heidelberg, Heidelberg, Germany
| |
Collapse
|
|
46
|
Jasser RA, AlSarhan M, Alotaibi D, Aloraini S, Koppolu P, Andreana S. Evaluation of clinical performance and survival rate of Straumann dental implants in Saudi Population based on cross-sectional study. Sci Rep 2021; 11:9526. [PMID: 33947951 PMCID: PMC8097015 DOI: 10.1038/s41598-021-89112-8] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.5] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/04/2020] [Accepted: 04/21/2021] [Indexed: 11/21/2022] Open
Abstract
Risk indicators of peri-implantitis is still contradictory and somehow unclear in present literature therefore efforts should be done for better understanding of the exact etiology of peri-implant disease progression. The present study aimed to assess risk indicators associated with peri-implantitis by observing the changes in several periodontal parameters after implant placement. This cross-sectional study included 213 female and 271 male patients aged 26–87 years, who received 484 titanium implants (Straumann, Switzerland) at King Saud University’s Dental College, Saudi Arabia. Patients were called for dental visits. During these visits; full clinical and radiographic assessment of implants were done. The periodontal pocket depth (PPD) was greater around implants placed at grafted sites than non-grafted sites and around bone-level implants than tissue-level implants. The plaque index (PI) was associated with poor oral hygiene. There was a strong association between graft (yes/no) and bleeding on probing (BOP). Patients with good oral hygiene showed high radiographic bone stability. Keratinized tissue width < 2 mm was associated with a higher PPD, higher PI, higher BOP, more edematous gingiva, and more exposed implant threads on radiography. In patients receiving implants, poor oral hygiene status and inadequate keratinized tissue level can be proposed as risk indicators for developing periimplantitis due to strong association found between them and developments of peri-implantitis.
Collapse
Affiliation(s)
- Reham Al Jasser
- Department of Periodontics and Community Dentistry, Dental College, King Saud University, Riyadh, Kingdom of Saudi Arabia.
| | - Mohammed AlSarhan
- Department of Periodontics and Community Dentistry, Dental College, King Saud University, Riyadh, Kingdom of Saudi Arabia
| | - Dalal Alotaibi
- Department of Periodontics and Community Dentistry, Dental College, King Saud University, Riyadh, Kingdom of Saudi Arabia
| | - Saleh Aloraini
- Department of Periodontics and Community Dentistry, Dental College, King Saud University, Riyadh, Kingdom of Saudi Arabia
| | - Pradeep Koppolu
- Department of Preventive Dental Sciences, College of Dentistry, Dar Al Uloom University, Riyadh, Kingdom of Saudi Arabia
| | - Sebastiano Andreana
- Department of Restorative Dentistry, State University of New York at Buffalo School of Dental Medicine, Buffalo, New York, USA
| |
Collapse
|
|
47
|
Lin CN, Ding SJ, Chen CC. Synergistic Photoantimicrobial Chemotherapy of Methylene Blue-Encapsulated Chitosan on Biofilm-Contaminated Titanium. Pharmaceuticals (Basel) 2021; 14:346. [PMID: 33918682 PMCID: PMC8069275 DOI: 10.3390/ph14040346] [Citation(s) in RCA: 7] [Impact Index Per Article: 1.8] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/15/2021] [Revised: 04/07/2021] [Accepted: 04/08/2021] [Indexed: 11/23/2022] Open
Abstract
Intensive efforts have been made to eliminate or substantial reduce bacterial adhesion and biofilm formation on titanium implants. However, in the management of peri-implantitis, the methylene blue (MB) photosensitizer commonly used in photoantimicrobial chemotherapy (PACT) is limited to a low retention on the implant surface. The purpose of this study was to assess enhancive effect of water-soluble quaternary ammonium chitosan (QTS) on MB retention on biofilm-infected SLA (sandblasted, large grid, and acid-etched) Ti alloy surfaces in vitro. The effectiveness of QTS + MB with different concentrations in eliminating Gram-negative A. actinomycetemcomitans or Gram-positive S. mutans bacteria was compared before and after PACT. Bacterial counting and lipopolysaccharide (LPS) detection were examined, and then the growth of human osteoblast-like MG63 cells was evaluated. The results indicated that the synergistic QTS + MB with retention ability significantly decreased the biofilm accumulation on the Ti alloy surface, which was better than the same concentration of 1 wt% methyl cellulose (MC). More importantly, the osteogenic activity of MG63 cells on the disinfected sample treated by QTS + MB-PACT modality was comparable to that of sterile Ti control, significantly higher than that by MC + MB-PACT modality. It is concluded that, in terms of improved retention efficacy, effective bacteria eradication, and enhanced cell growth, synergistically, PACT using the 100 μg/mL MB-encapsulated 1% QTS was a promising modality for the treatment of peri-implantitis.
Collapse
Affiliation(s)
- Chiu-Nan Lin
- Institute of Oral Science, Chung Shan Medical University, Taichung City 402, Taiwan;
| | - Shinn-Jyh Ding
- Institute of Oral Science, Chung Shan Medical University, Taichung City 402, Taiwan;
- Department of Stomatology, Chung Shan Medical University Hospital, Taichung City 402, Taiwan
| | - Chun-Cheng Chen
- Department of Stomatology, Chung Shan Medical University Hospital, Taichung City 402, Taiwan
- School of Dentistry, Chung Shan Medical University, Taichung City 402, Taiwan
| |
Collapse
|
|
48
|
Orchestrating soft tissue integration at the transmucosal region of titanium implants. Acta Biomater 2021; 124:33-49. [PMID: 33444803 DOI: 10.1016/j.actbio.2021.01.001] [Citation(s) in RCA: 78] [Impact Index Per Article: 19.5] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/09/2020] [Revised: 01/03/2021] [Accepted: 01/05/2021] [Indexed: 12/20/2022]
Abstract
Osseointegration at the bone-implant interface and soft tissue integration (STI) at the trans-mucosal region are crucial for the long-term success of dental implants, especially in compromised patient conditions. The STI quality of conventional smooth and bio-inert titanium-based implants is inferior to that of natural tissue (i.e. teeth), and hence various surface modifications have been suggested. This review article compares and contrasts the various modification strategies (physical, chemical and biological) utilized to enhance STI of Ti implants. It also details the STI challenges associated with conventional Ti-based implants, current surface modification strategies and cutting-edge nano-engineering solutions. The topographical, biological and therapeutic advances achievable via electrochemically anodized Ti implants with TiO2 nanotubes/nanopores are highlighted. Finally, the status and future directions of such nano-engineered implants is discussed, with emphasis on bridging the gap between research and clinical translation.
Collapse
|
|
49
|
Stavropoulos A, Sandgren R, Bellon B, Sculean A, Pippenger BE. Greater Osseointegration Potential with Nanostructured Surfaces on TiZr: Accelerated vs. Real-Time Ageing. MATERIALS 2021; 14:ma14071678. [PMID: 33805477 PMCID: PMC8036800 DOI: 10.3390/ma14071678] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 01/26/2021] [Revised: 03/16/2021] [Accepted: 03/22/2021] [Indexed: 11/16/2022]
Abstract
Surface chemistry and nanotopography of dental implants can have a substantial impact on osseointegration. The aim of this investigation was to evaluate the effects of surface chemistry and nanotopography on the osseointegration of titanium-zirconium (TiZr; Roxolid®) discs, using a biomechanical pull-out model in rabbits. Two discs each were placed in both the right and left tibiae of 16 rabbits. Five groups of sandblasted acid etched (SLA) discs were tested: (1) hydrophobic without nanostructures (dry/micro) (n = 13); (2) hydrophobic with nanostructures, accelerated aged (dry/nano/AA) (n = 12); (3) hydrophilic without nanostructures (wet/micro) (n = 13); (4) hydrophilic with nanostructures, accelerated aged (wet/nano/AA; SLActive®) (n = 13); (5) hydrophilic with nanostructures, real-time aged (wet/nano/RTA). The animals were sacrificed after four weeks and the biomechanical pull-out force required to remove the discs was evaluated. Adjusted mean pull-out force was greatest for group wet/nano/RTA (64.5 ± 17.7 N) and lowest for group dry/micro (33.8 ± 10.7 N). Multivariate mixed model analysis showed that the pull-out force was significantly greater for all other disc types compared to the dry/micro group. Surface chemistry and topography both had a significant effect on pull-out force (p < 0.0001 for both), but the effect of the interaction between chemistry and topography was not significant (p = 0.1056). The introduction of nanostructures on the TiZr surface significantly increases osseointegration. The introduction of hydrophilicity to the TiZr implant surface significantly increases the capacity for osseointegration, irrespective of the presence or absence of nanotopography.
Collapse
Affiliation(s)
- Andreas Stavropoulos
- Division of Regenerative Dental Medicine and Periodontology, University of Geneva, CH-1211 Genève 4, Switzerland
- Department of Periodontology, Faculty of Odontology, Malmö University, SE-205 06 Malmö, Sweden
- Division of Conservative Dentistry and Periodontology, University Clinic of Dentistry, Medical University of Vienna, AT-1090 Vienna, Austria
- Correspondence: or (A.S.); (B.E.P.)
| | - Rebecca Sandgren
- Department of Biomedicine, Medical Faculty, Lunds University, SE-223 62 Lund, Sweden;
| | - Benjamin Bellon
- Department of Preclinical & Translational Research, Institut Straumann, CH-4002 Basel, Switzerland;
- Department of Periodontology, Faculty of Dentistry, University of Zurich, CH-8032 Zurich, Switzerland
| | - Anton Sculean
- Department of Periodontology, School of Dental Medicine, University of Bern, CH-3210 Bern, Switzerland;
| | - Benjamin E. Pippenger
- Department of Preclinical & Translational Research, Institut Straumann, CH-4002 Basel, Switzerland;
- Department of Periodontology, School of Dental Medicine, University of Bern, CH-3210 Bern, Switzerland;
- Correspondence: or (A.S.); (B.E.P.)
| |
Collapse
|
|
50
|
Hoellwarth JS, Tetsworth K, Rozbruch SR, Handal MB, Coughlan A, Al Muderis M. Osseointegration for Amputees: Current Implants, Techniques, and Future Directions. JBJS Rev 2021; 8:e0043. [PMID: 32224634 PMCID: PMC7161721 DOI: 10.2106/jbjs.rvw.19.00043] [Citation(s) in RCA: 82] [Impact Index Per Article: 20.5] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 01/26/2023]
Abstract
Osseointegrated prostheses provide a rehabilitation option for amputees offering greater mobility, better satisfaction, and higher use than traditional socket prostheses. There are several different osseointegrated implant designs, surgical techniques, and rehabilitation protocols with their own strengths and limitations. The 2 most prominent risks, infection and periprosthetic fracture, do not seem unacceptably frequent or insurmountable. Proximal amputations or situations leading to reduced mobility are exceptionally infrequent. Osseointegrated implants can be attached to advanced sensory and motor prostheses.
Collapse
Affiliation(s)
- Jason Shih Hoellwarth
- Department of Orthopaedic Surgery, Macquarie University Hospital, Sydney, New South Wales, Australia
| | - Kevin Tetsworth
- Department of Orthopaedics, The Royal Brisbane Hospital, Brisbane, Victoria, Australia
| | - S Robert Rozbruch
- Limb Lengthening and Complex Reconstruction Service, Hospital for Special Surgery, New York, NY
| | - M Brianne Handal
- Geisinger Commonwealth School of Medicine, Scranton, Pennsylvania
| | - Adam Coughlan
- Department of Orthopaedics, The Royal Brisbane Hospital, Brisbane, Victoria, Australia
| | - Munjed Al Muderis
- Department of Orthopaedic Surgery, Macquarie University Hospital, Sydney, New South Wales, Australia
| |
Collapse
|