Like father, like son: Pulmonary thromboembolism due to inflammatory or hereditary condition? Two case reports

Table 1 Laboratory tests and imaging studies for both patients showing altered findings

Laboratory tests and imaging studies	Father (older patient)	Son (younger patient)	Normal values and conditions
C-reactive protein (mg/L)	4.6	44.8	< 1.2
Toxoplasma gondii IgM antibodies (UI/mL)	19.8	30.8	< 0.5
FVL mutation status (gene F5, c.691G>A, p.R506Q)	Heterozygosis	Heterozygosis	Unmutated
D-dimer (ng/mL)	5.724	Not performed	< 500
Lower limbs Doppler ultrasound	Absent blood flow in anterior tibial, posterior tibial, and fibular veins in the left leg	Absent blood flow in anterior tibial, posterior tibial, fibular, and popliteal veins in the right leg	Presence of blood flow in the veins
Chest CT scan	Filling defects in segmental and subsegmental arterial branches in upper and lower lobes of both lungs (Figure 1A)	Filling defects in segmental and subsegmental arterial branches in lower lobes of both lungs and in apical subsegmental artery of right lung(Figure 1B)	Absence of filling defects in the arteries

FVL: Factor V Leiden; CT: Computed tomography.