Original Article
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World J Otorhinolaryngol. Feb 28, 2012; 2(1): 1-7
Published online Feb 28, 2012. doi: 10.5319/wjo.v2.i1.1
Effects of p27Kip1- and p53- shRNAs on kanamycin damaged mouse cochlea
Laura Pietola, Jussi Jero, Reetta Jalkanen, Teemu J Kinnari, Olga Jero, Mikko Frilander, Katri Pajusola, Marjo Salminen, Antti A Aarnisalo
Laura Pietola, Jussi Jero, Teemu J Kinnari, Olga Jero, Antti A Aarnisalo, Department of Otorhinolaryngology, University of Helsinki, 00014 Helsinki, Finland
Reetta Jalkanen, Folkhälsan Institute of Genetics, Biomedicum Helsinki, 00014 Helsinki, Finland
Mikko Frilander, Institute of Biotechnology, University of Helsinki, 00014 Helsinki, Finland
Katri Pajusola, Molecular Cancer Biology Program, Biomedicum Helsinki, 00014 Helsinki, Finland
Marjo Salminen, Department of Basic Veterinary Science, Division of Biochemistry, University of Helsinki, 00014 Helsinki, Finland
Author contributions: Pietola L, Jero J, Jalkanen R, Kinnari TJ, Jero O and Aarnisalo AA performed the research and analyzed the data; Jero J, Salminen M and Aarnisalo AA designed the research; Frilander M and Pajusola K contributed shRNAs and virus vectors; Pietola L, Jero J, Jalkanen R, Salminen M and Aarnisalo AA wrote the paper.
Supported by grants from a Helsinki University Central Hospital Research Funds; the Sigrid Jusélius Foundation; the Instrumentarium Research Foundation; and the Finnish Medical Foundation.
Correspondence to: Antti A Aarnisalo, MD, PhD, Department of Otorhinolaryngology, University of Helsinki, 00014 Helsinki, Finland. antti.aarnisalo@hus.fi
Telephone: +358-9-4711 Fax: +358-9-47175010
Received: March 22, 2011
Revised: November 2, 2011
Accepted: February 27, 2012
Published online: February 28, 2012
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