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Retrospective Cohort Study
Copyright: ©Author(s) 2026.
World J Ophthalmol. Sep 12, 2026; 10(1): 121730
Published online Sep 12, 2026. doi: 10.5318/wjo.121730
Table 1 Inter-period change in spherical equivalent refraction between the atropine and control groups (mean ± SD, diopters)
Time interval
Control group (n = 35)
Atropine group (n = 35)
P value
0-6 months vs baseline0.51 ± 0.460.26 ± 0.290.008b
6-12 months0.31 ± 0.290.31 ± 0.341.00
12-18 months0.37 ± 0.320.18 ± 0.250.009b
18-24 months0.42 ± 0.310.29 ± 0.240.071
Table 2 Absolute spherical equivalent refraction values at each time point for the atropine and control groups (mean ± SD, diopters)
Time interval
Control group (n = 35)
Atropine group (n = 35)
P value
Baseline2.71 ± 0.983.99 ± 1.50< 0.001b
6 months3.22 ± 1.074.24 ± 1.490.003b
12 months3.54 ± 1.094.52 ± 1.440.003b
18 months3.91 ± 1.134.73 ± 1.500.015a
24 months4.33 ± 1.255.01 ± 1.490.057


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