Brief Article
Copyright ©2011 Baishideng Publishing Group Co.
World J Ophthalmol. Dec 30, 2011; 1(1): 4-10
Published online Dec 30, 2011. doi: 10.5318/wjo.v1.i1.4
Table 1 Demographic and clinical features of the studied patients
ParametersSurgery groupControl groupP value1
No. of patients35
Age (yr)62.2 ± 2.5
Gender
Male18 (51%)
Female17 (49%)
Diabetes mellitus8
Hypertension25
Cup/Disc ratio0.76 ± 2.40.57 ± 2.1F = 3.52
P = 0.0121
IOP diurnal range212.17 ± 2.218.26 ± 3.31F = 4.64
P = 0.0151
Preoperative IOP (mmHg)23.4 ± 6.118.5 ± 2.3F = 3.54
P = 0.0151
Preoperative medication3.1 ± 0.51.7 ± 0.4F = 2.56
P = 0.0211
Preoperative VF MD (dB) -9.2 ± 5.3 -4.5 ± 4.1F = 4.21
P = 0.0171
Preoperative VF PSD (dB)5.7 ± 3.14.8 ± 2.9F = 4.56
P = 0.25
Preoperative VA (logMAR)0.73 ± 0.40.86 ± 0.2F = 3.61
P = 0.36
Table 2 Mean peripapillary retinal nerve fiber layer thickness measurements in eyes that underwent deep sclerectomy compared with the contralateral eye of the same patient as measured by optical coherence tomography
ParameterPre-operative (μm)Post-operative (μm)P value1
Overall
Surgery group71.6 ± 18.689.5 ± 21.20.0151
Control group72.5 ± 17.871.7 ± 20.30.165
Superior quadrant
Surgery group85.8 ± 25.196.7 ± 23.20.0211
Control group85.7 ± 24.186.5 ± 21.50.114
Nasal quadrant
Surgery group54.6 ± 21.572.0 ± 25.10.0141
Control group56.5 ± 18.958.2 ± 22.10.356
Inferior quadrant
Surgery group81.3 ± 25.169.2 ± 22.50.0231
Control group83.1 ± 18.283.3 ± 20.10.453
Temporal quadrant
Surgery group56.2 ± 19.275.2 ± 20.10.0161
Control group57.0 ± 18.558.1 ± 21.50.451
Table 3 Pearson's correlation between change in mean retinal nerve fiber layer thickness and age, intraocular pressure, and global visual field indices in the surgery group
rP value1
Age-0.1640.276
IOP change (mmHg)-0.2350.023
IOP change (%)-0.4530.036
BCVA-0.1530.216
Preoperative VF MD (dB) 0.3740.075
Preoperative VF PSD (dB)-0.1820.383
Change in VF MD  0.3950.064
Change in VF PSD 0.1860.625