Variation in risk factors of dementia among four elderly patient cohorts

Table 1 Clinical characteristics of dementia patients by race and gender cohorts

Variables	White males	White females	All white	Black males	Black female	All black	All dementia age 65+
	n = 1778	n = 3069	n = 9847	n = 253	n = 456	n = 709	n = 5556
Column→	1	2	3	4	5	6	7
Mean age (SD)	80.6 (8.4)	83.9 (9.0)	82.7 (9)	78.4 (8.8)	82.3 (9.4)	80.9 (9.4)	82.5 (9.1)
HTN (%)	81.8	83.1	82.6	85.8	91.71	89.62	83.5
DM (%)	38.1	30.6	33.4	47.2	52.61	50.62	35.6
Chol (%)	11.31	8.5	9.6	8.7	9.4	9.2	9.5
CA (%)	42.41	36.3	38.61	35.6	32.5	33.6	37.9
MI (%)	7.6	5.3	6.2	7.91	5.7	6.5	6.2
CHF (%)	36.71	32.6	34.0	32.4	36.2	34.8	34.2
Stroke (%)	63.1	54.9	57.9	72.71	63.4	66.71	59.0
Dementia (%)	3.1	3.8	3.5	4.1	4.21	4.21	3.6

¹Differences across cohorts significant at P < 0.001;

²Differences between two racial groups (cols. 3 and 6) are significant at P < 0.001. HTN: Hypertension; DM: Diabetes mellitus; Chol: Hyperlipidemia; CA: Cardiac arrhythmia; MI: Myocardial infarction; CHF: Congestive heart failure; Stroke: Prior stroke.

Table 2 Odds ratios showing direct effect of risk factors on dementia by race-gender cohorts

Risk factors	White males	White females	All white	Black males	Black females	All black	All dementia patients
Column→	1	2	3	4	5	6	7
HTN	1.222	1.101	1.152	0.72	1.04 ns	0.88	1.133
DM	1.162	1.162	1.162	1.17 ns	1.283	1.243	1.172
Chol	0.78	0.73	0.75	0.81	0.89	0.85	0.76
CA	0.91	0.89	0.89	1.05 ns	1.03 ns	1.04 ns	0.91
CHF	1.443	1.162	1.262	1.14 ns	1.19 ns	1.17 ns	1.253
MI	0.84	0.83	0.83	1.11 ns	0.8	0.92	0.84
Stroke	9.93	7.83	8.233	13.33	9.23	10.393	8.53

¹Each logistic analysis included age in model, OR significant at P < 0.05;

²OR significant at P < 0.01,

³OR significant at P < 0.000; HTN: Hypertension; DM: Diabetes mellitus; Chol: Hyperlipidemia; CA: Cardiac arrhythmia; MI: Myocardial infarction; CHF: Congestive heart failure; Stroke: Prior stroke.