Copyright ©The Author(s) 2015.
World J Hematol. Aug 6, 2015; 4(3): 16-53
Published online Aug 6, 2015. doi: 10.5315/wjh.v4.i3.16
Figure 2
Figure 2 Reciprocal translocation t(9;22)(q34;q11) creates a novel breakpoint cluster region/ABL fusion gene with high tyrosinase activity as the cause of chronic myeloid leukemia. A: Dr. Janet Rowley, discoverer of t(9;22)(q34;q11) in Ph1chromosome positive chronic myeloid leukemia (CML)[19,20], and winner the Beutler Prize 2011, American Society of Hematology (ASH). Photo courtesy of ASH 2012; B: The discoverers of BCR/ABL fusion gene as the cause of Ph+ CML[21-24]. From left behind to right Gerard Grosveld, John Groffen and Nora Heisterkamp.