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For: Simpson EL, Bieber T, Guttman-Yassky E, Beck LA, Blauvelt A, Cork MJ, Silverberg JI, Deleuran M, Kataoka Y, Lacour JP, Kingo K, Worm M, Poulin Y, Wollenberg A, Soo Y, Graham NMH, Pirozzi G, Akinlade B, Staudinger H, Mastey V, Eckert L, Gadkari A, Stahl N, Yancopoulos GD, Ardeleanu M. Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis. N Engl J Med 2016;375:2335-2348. [PMID: 27690741 DOI: 10.1056/nejmoa1610020] [Citation(s) in RCA: 1394] [Impact Index Per Article: 154.9] [Reference Citation Analysis] [What about the content of this article? (0)] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 12/12/2022]
Number Cited by Other Article(s)
1
Liming W, Ali K. Efficacy of dupilumab with concomitant topical calcineurin inhibitors treatment for preschool children with atopic dermatitis: a retrospective cohort study. Ann Med 2025;57:2449589. [PMID: 39757933 PMCID: PMC11705541 DOI: 10.1080/07853890.2025.2449589] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 09/26/2023] [Revised: 07/27/2024] [Accepted: 11/28/2024] [Indexed: 01/07/2025]  Open
2
Mense SA, Maher S, Chovatiya R. A Practical Approach to Chronic Hand Eczema. Dermatol Ther (Heidelb) 2025;15:1953-1971. [PMID: 40382744 DOI: 10.1007/s13555-025-01433-y] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/04/2025] [Accepted: 04/22/2025] [Indexed: 05/20/2025]  Open
3
Domíguez-Hüttinger E, Flores-Garza E, Caldú-Primo JL, Day H, Roque Ramírez A, Tanaka RJ. History-dependent switch-like differentiation of keratinocytes in response to skin barrier damage. PLoS Comput Biol 2025;21:e1013162. [PMID: 40489727 DOI: 10.1371/journal.pcbi.1013162] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/09/2024] [Accepted: 05/24/2025] [Indexed: 06/11/2025]  Open
4
Mochizuki K, Takeoka J, Toda N, Otsuka K, Sato R, Kurahashi S, Fujita K, Hirashima H, Ishii A, Komiya T. A case of systemic contact dermatitis associated with a peritoneal dialysis catheter and treated with dupilumab. CEN Case Rep 2025;14:450-454. [PMID: 40053283 DOI: 10.1007/s13730-025-00980-9] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/09/2024] [Accepted: 02/17/2025] [Indexed: 06/02/2025]  Open
5
Yew YW, Loh M, Brown SJ. Understanding Atopic Dermatitis in Asian and European Population Cohorts Using Complementary Omics Techniques. J Invest Dermatol 2025;145:1283-1293. [PMID: 39503693 DOI: 10.1016/j.jid.2024.08.036] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/16/2024] [Revised: 08/14/2024] [Accepted: 08/15/2024] [Indexed: 11/08/2024]
6
Jacobson ME, Boesjes CM, de Bruin-Weller MS, de Graaf M, Morimoto RY, Simpson EL. Increasing dosing intervals for biologics in atopic dermatitis-why, who, when and how? J Eur Acad Dermatol Venereol 2025;39:1099-1107. [PMID: 39840710 DOI: 10.1111/jdv.20534] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/16/2024] [Accepted: 12/10/2024] [Indexed: 01/23/2025]
7
Powers CM, Thakker S, Gulati N, Talia J, Dubin D, Zone J, Culton DA, Hopkins Z, Adalsteinsson JA. Bullous pemphigoid: A practical approach to diagnosis and management in the modern era. J Am Acad Dermatol 2025;92:1337-1350. [PMID: 39914667 DOI: 10.1016/j.jaad.2025.01.086] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/02/2024] [Revised: 01/28/2025] [Accepted: 01/30/2025] [Indexed: 02/23/2025]
8
Bhatia N, Lynde CW, Fonacier L, Shao L, Korotzer A, Bosman K. Complete/Near-Complete Itch Response Observed in Patients with Moderate-to-Severe Atopic Dermatitis Initiating Dupilumab: 3-Year, Real-World, Interim Data from the PROSE Registry. Dermatol Ther (Heidelb) 2025;15:1523-1531. [PMID: 40234297 PMCID: PMC12092847 DOI: 10.1007/s13555-025-01395-1] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/27/2024] [Accepted: 03/19/2025] [Indexed: 04/17/2025]  Open
9
Silverberg JI, Mustapa MN, Reid F, Lei A, Smith R, Moate R, Kelly A, Chen R, Gavala M, Jimenez E, Belvisi MG, Sadiq MW, Kell C, Pandya HC. Efficacy and safety of tozorakimab in moderate-to-severe atopic dermatitis: A Phase 2a randomized controlled trial (FRONTIER-2). J Eur Acad Dermatol Venereol 2025;39:1126-1133. [PMID: 39535462 DOI: 10.1111/jdv.20388] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/20/2024] [Accepted: 09/16/2024] [Indexed: 11/16/2024]
10
Lavin L, Geller S. Cutaneous T Cell Lymphoma Following Dupilumab Therapy in Patients with Atopic Dermatitis: Clinical Review and Recommendations. Am J Clin Dermatol 2025:10.1007/s40257-025-00955-7. [PMID: 40418285 DOI: 10.1007/s40257-025-00955-7] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 05/12/2025] [Indexed: 05/27/2025]
11
Horie A, Miyagaki T, Hiranuma C, Iijima M, Hara Y, Oba S, Hashimoto M, Omori R, Okano T, Kadono T. Clinical Effectiveness, Clinical Stability, and Effects on Serum Galectin-7 Levels of Dupilumab and JAK Inhibitors in Moderate-to-Severe Atopic Dermatitis: A Real-World, Single-Center Analysis. MEDICINA (KAUNAS, LITHUANIA) 2025;61:926. [PMID: 40428884 PMCID: PMC12113402 DOI: 10.3390/medicina61050926] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 04/21/2025] [Revised: 05/12/2025] [Accepted: 05/19/2025] [Indexed: 05/29/2025]
12
Guglielmo A, Borghi A, Schettini N, Perillo M, Corazza M, Piraccini BM, Pileri A. Mycosis fungoides and IL-4/13 inhibitors: what is known and unmet needs. Expert Rev Clin Immunol 2025:1-7. [PMID: 40369852 DOI: 10.1080/1744666x.2025.2507332] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/25/2025] [Revised: 04/22/2025] [Accepted: 05/13/2025] [Indexed: 05/16/2025]
13
Liu D, Patel D, Lau M, Largen J, Hu BD, He H, Guttman-Yassky E. A translational approach to improve therapeutics in atopic dermatitis and beyond. JOURNAL OF IMMUNOLOGY (BALTIMORE, MD. : 1950) 2025:vkaf049. [PMID: 40373271 DOI: 10.1093/jimmun/vkaf049] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Subscribe] [Scholar Register] [Received: 10/15/2024] [Accepted: 03/03/2025] [Indexed: 05/17/2025]
14
Kim BS, Artis D. The sensory neuroimmune frontier. Immunity 2025;58:1033-1039. [PMID: 40324378 DOI: 10.1016/j.immuni.2025.03.018] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/09/2025] [Revised: 03/21/2025] [Accepted: 03/25/2025] [Indexed: 05/07/2025]
15
Thio CLP, Shao JS, Luo CH, Chang YJ. Decoding innate lymphoid cells and innate-like lymphocytes in asthma: pathways to mechanisms and therapies. J Biomed Sci 2025;32:48. [PMID: 40355861 PMCID: PMC12067961 DOI: 10.1186/s12929-025-01142-w] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/05/2025] [Accepted: 04/29/2025] [Indexed: 05/15/2025]  Open
16
Kamata M, Sun DI, Paller AS. Deciding Which Patients With Atopic Dermatitis to Prioritize for Biologics and Janus Kinase Inhibitors. THE JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. IN PRACTICE 2025:S2213-2198(25)00411-8. [PMID: 40368249 DOI: 10.1016/j.jaip.2025.04.042] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Subscribe] [Scholar Register] [Received: 01/17/2025] [Revised: 04/20/2025] [Accepted: 04/23/2025] [Indexed: 05/16/2025]
17
Béal L, Lamiaux M, Guerrien-Sevrin E, Lasek A, Modiano P, Doan S, Tran THC. Ocular surface evaluation in atopic dermatitis patients on dupilumab: A prospective observational study. J Fr Ophtalmol 2025;48:104544. [PMID: 40339460 DOI: 10.1016/j.jfo.2025.104544] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/02/2024] [Revised: 02/02/2025] [Accepted: 03/24/2025] [Indexed: 05/10/2025]
18
Wollenberg A, Kinberger M, Arents B, Aszodi N, Barbarot S, Bieber T, Brough HA, Calzavara-Pinton P, Christen-Zaech S, Deleuran M, Dittmann M, Fosse N, Gáspár K, Gerbens LAA, Gieler U, Girolomoni G, Gregoriou S, Holland S, Mortz CG, Nast A, Nygaard U, Rehbinder EM, Ring J, Rossi M, Serra-Baldrich E, Simon D, Szalai ZZ, Szepietowski JC, Torrelo A, Werfel T, Werner RN, Flohr C. European Guideline (EuroGuiDerm) on atopic eczema: Living update. J Eur Acad Dermatol Venereol 2025. [PMID: 40317496 DOI: 10.1111/jdv.20639] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/12/2025] [Accepted: 02/21/2025] [Indexed: 05/07/2025]
19
Gu S, Xu L, Huang B, Xiong K, Yang X, Ye J. Decoding Macrophage Dynamics: A Pathway to Understanding and Treating Inflammatory Skin Diseases. Int J Mol Sci 2025;26:4287. [PMID: 40362523 PMCID: PMC12071885 DOI: 10.3390/ijms26094287] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/05/2025] [Revised: 04/27/2025] [Accepted: 04/29/2025] [Indexed: 05/15/2025]  Open
20
Blunder S, Hermann-Kleiter N, Mahmuti R, Hermann M, Ortner D, Reider D, Moosbrugger-Martinz V, Del Frari B, Stoitzner P, Dubrac S, Schmuth M, Gruber R. Blocking of IL-4/IL-13 Signalling With Dupilumab Results in Restoration of Serum and Cutaneous Abnormalities in Netherton Syndrome. Exp Dermatol 2025;34:e70113. [PMID: 40344324 DOI: 10.1111/exd.70113] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/23/2025] [Revised: 04/02/2025] [Accepted: 04/13/2025] [Indexed: 05/11/2025]
21
Guttman-Yassky E, Rosmarin D, de Bruin-Weller M, Weidinger S, Bieber T, Hong HCH, Elmaraghy H, Atwater AR, Pierce E, Xu C, Agell H, Garcia Gil E, Simpson E. The efficacy of longer-term lebrikizumab treatment in patients with moderate-to-severe atopic dermatitis who did not meet protocol-defined response criteria at week 16 in 2 randomized controlled clinical trials. J Am Acad Dermatol 2025;92:1024-1031. [PMID: 39733939 DOI: 10.1016/j.jaad.2024.12.026] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/27/2023] [Revised: 11/06/2024] [Accepted: 12/04/2024] [Indexed: 12/31/2024]
22
Rønnstad ATM, Bunick CG, Chovatiya R, Kamata M, Nielsen ML, Isufi D, Thomsen SF, Vestergaard C, Wollenberg A, Egeberg A, Thyssen JP, Loft N. Real-World Evidence of Tralokinumab Effectiveness and Safety: A Systematic Review and Meta-analysis. Am J Clin Dermatol 2025;26:411-424. [PMID: 40045152 DOI: 10.1007/s40257-025-00927-x] [Citation(s) in RCA: 2] [Impact Index Per Article: 2.0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 02/03/2025] [Indexed: 04/25/2025]
23
Polaskey MT, Fakhraie S, Daftary K, Chovatiya R. An Open-Label Prospective Observational Study of Tralokinumab in Atopic Dermatitis Patients with Inadequate Response to Dupilumab. Dermatitis 2025;36:e309-e311. [PMID: 39088279 DOI: 10.1089/derm.2024.0084] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 08/03/2024]
24
Cassagne M, Galiacy S, Kychygina A, Chapotot E, Wallaert M, Vabres B, Tauber M, Barbarot S, Paul C, Fournié P, Simon M. Superficial Conjunctival Cells from Dupilumab-Treated Patients with Atopic Dermatitis with Ocular Adverse Events Display a Transcriptomic Psoriasis Signature. J Invest Dermatol 2025;145:1050-1059.e6. [PMID: 39306032 DOI: 10.1016/j.jid.2024.08.024] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/05/2024] [Revised: 07/22/2024] [Accepted: 08/02/2024] [Indexed: 11/04/2024]
25
Zhao Y, Gooderham M, Yang B, Wu J, Wu L, Loo WJ, Toth D, Sauder M, Li J, Chen A, Tao X, Lu J, Song Z, Han J, Li H, Li Y, Xu L, Zhang J. Ivarmacitinib for Moderate to Severe Atopic Dermatitis in Adults and Adolescents: A Phase 3 Randomized Clinical Trial. JAMA Dermatol 2025:2833318. [PMID: 40305055 PMCID: PMC12044538 DOI: 10.1001/jamadermatol.2025.0982] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/25/2024] [Accepted: 03/10/2025] [Indexed: 05/02/2025]
26
Mima Y, Yamamoto M, Iozumi K. Cutaneous Adverse Events Following Nemolizumab Administration: A Review. J Clin Med 2025;14:3026. [PMID: 40364058 PMCID: PMC12072469 DOI: 10.3390/jcm14093026] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/04/2025] [Revised: 04/25/2025] [Accepted: 04/25/2025] [Indexed: 05/15/2025]  Open
27
Abu-Ghazaleh N, Ross G, Morgan V. Upadacitinib Drug Survival in the Management of Patients With Moderate to Severe Atopic Dermatitis: Real-Time Data From the Biogrid Database Registry. Australas J Dermatol 2025. [PMID: 40248987 DOI: 10.1111/ajd.14469] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/17/2025] [Revised: 03/11/2025] [Accepted: 03/21/2025] [Indexed: 04/19/2025]
28
DeBerg HA, Fahning ML, Varkhande SR, Schlenker JD, Schmitt WP, Gupta A, Singh A, Gratz IK, Carlin JS, Campbell DJ, Morawski PA. T Cells Promote Distinct Transcriptional Programs of Cutaneous Inflammatory Disease in Keratinocytes and Dermal Fibroblasts. J Invest Dermatol 2025:S0022-202X(25)00401-4. [PMID: 40216155 DOI: 10.1016/j.jid.2025.03.033] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/30/2024] [Revised: 03/06/2025] [Accepted: 03/23/2025] [Indexed: 04/25/2025]
29
Alraddadi R, Kalantan M, Aljefri Y, Maaddawi H, Alsamadani A, Kadasa A, Softah A, Tabbakh B, Alturkistani R, Jfri A. Incidence of upper respiratory tract infections with biological therapies in moderate to severe atopic dermatitis: a systematic review and meta-analysis. Front Med (Lausanne) 2025;12:1550640. [PMID: 40241901 PMCID: PMC12000152 DOI: 10.3389/fmed.2025.1550640] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/23/2024] [Accepted: 03/17/2025] [Indexed: 04/18/2025]  Open
30
Li R, Zhang J, Wang L, Zhang LY. Comments on "Dupilumab and neuropsychiatric outcomes in pediatric atopic dermatitis: A real-world cohort analysis". J Am Acad Dermatol 2025:S0190-9622(25)00554-7. [PMID: 40180128 DOI: 10.1016/j.jaad.2025.03.080] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/18/2025] [Revised: 03/26/2025] [Accepted: 03/27/2025] [Indexed: 04/05/2025]
31
D'Auria E, Indolfi C, Acunzo M, Dinardo G, Comberiati P, Peroni D, Zuccotti GV, Miraglia Del Giudice M. Biologics and small molecules: the re-evolution in the treatment of atopic dermatitis in children and adolescents. Current state of the art and future perspectives. Expert Rev Clin Immunol 2025;21:493-505. [PMID: 39810497 DOI: 10.1080/1744666x.2025.2452247] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/11/2024] [Revised: 10/28/2024] [Accepted: 01/08/2025] [Indexed: 01/16/2025]
32
Kido-Nakahara M, Chiba T, Mizusawa Y, Higashi Y, Ibusuki A, Igawa S, Murakami Y, Matsunaka H, Kuba-Fuyuno Y, Tsuji G, Nakahara T. Cytokine profile of the stratum corneum in atopic dermatitis lesions differs between the face and the trunk. Allergol Int 2025;74:222-232. [PMID: 39332980 DOI: 10.1016/j.alit.2024.08.010] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/31/2024] [Revised: 08/13/2024] [Accepted: 08/31/2024] [Indexed: 09/29/2024]  Open
33
Blicharz L, Michalczyk A, Maj M, Czuwara J, Olszewska M, Rudnicka L. Head and neck dermatitis: a variant of atopic dermatitis. Ital J Dermatol Venerol 2025;160:123-144. [PMID: 40248964 DOI: 10.23736/s2784-8671.25.08001-6] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 04/19/2025]
34
Weidinger S, Blauvelt A, Papp KA, Reich A, Lee CH, Worm M, Lynde C, Kataoka Y, Foley P, Wei X, Wong W, Solente AC, Weber C, Adelman S, Davey S, Hurbin F, Rynkiewicz N, Yen K, O'Malley JT, Bernigaud C. Phase 2b randomized clinical trial of amlitelimab, an anti-OX40 ligand antibody, in patients with moderate-to-severe atopic dermatitis. J Allergy Clin Immunol 2025;155:1264-1275. [PMID: 39522654 DOI: 10.1016/j.jaci.2024.10.031] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/26/2024] [Revised: 09/27/2024] [Accepted: 10/24/2024] [Indexed: 11/16/2024]
35
Saeki H, Ohya Y, Arakawa H, Ichiyama S, Katsunuma T, Katoh N, Tanaka A, Tanizaki H, Tsunemi Y, Nakahara T, Nagao M, Narita M, Hide M, Fujisawa T, Futamura M, Masuda K, Matsubara T, Murota H, Yamamoto-Hanada K, Furuta J. Executive summary: Japanese guidelines for atopic dermatitis (ADGL) 2024. Allergol Int 2025;74:210-221. [PMID: 39986987 DOI: 10.1016/j.alit.2025.01.003] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/24/2024] [Accepted: 01/23/2025] [Indexed: 02/24/2025]  Open
36
Ständer S, Yosipovitch G, Simpson EL, Kim BS, Kabashima K, Thaçi D, Metz M, Chen Z, Hagen S, Bastian M. Onset and Long-Term Maintenance of Optimal Itch Response in Adult Patients with Moderate-to-Severe Atopic Dermatitis Treated with Dupilumab: Post Hoc Analysis from Two Phase 3 Trials. Adv Ther 2025;42:1800-1810. [PMID: 39969783 PMCID: PMC11929679 DOI: 10.1007/s12325-025-03124-8] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/14/2024] [Accepted: 01/21/2025] [Indexed: 02/20/2025]
37
Cai R, Huang J, Chen C, Ye Z, Cheng B. Efficacy and Safety of Dupilumab in the Treatment of Refractory Atopic Dermatitis in Older Adults: A Retrospective, Single-Center Study. Drugs Aging 2025;42:363-371. [PMID: 40186050 DOI: 10.1007/s40266-025-01193-6] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 02/17/2025] [Indexed: 04/07/2025]
38
Han C, Zhu X, Sokol CL. Neuroimmune Circuits in Allergic Diseases. Annu Rev Immunol 2025;43:367-394. [PMID: 39977604 DOI: 10.1146/annurev-immunol-082423-032154] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 02/22/2025]
39
Nakajima S, Yonekura S, Kabashima K. Targeting the OX40-OX40L pathway: A new era in atopic dermatitis management by T-cell rebalancing. J Allergy Clin Immunol 2025;155:1211-1213. [PMID: 39978683 DOI: 10.1016/j.jaci.2025.02.007] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/13/2024] [Revised: 02/04/2025] [Accepted: 02/13/2025] [Indexed: 02/22/2025]
40
Tamari M, Ver Heul AM. Neuroimmune mechanisms of type 2 inflammation in the skin and lung. Allergol Int 2025;74:177-186. [PMID: 40064568 DOI: 10.1016/j.alit.2025.02.001] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/20/2025] [Revised: 02/10/2025] [Accepted: 02/12/2025] [Indexed: 04/01/2025]  Open
41
Chovatiya R, Ribero S, Wollenberg A, Park CO, Silvestre JF, Hong HCH, Seneschal J, Saeki H, Thyssen JP, Øland CB, Gjerum L, Maslin D, Blauvelt A. Long-Term Disease Control and Minimal Disease Activity of Head and Neck Atopic Dermatitis in Patients Treated with Tralokinumab up to 4 Years. Am J Clin Dermatol 2025:10.1007/s40257-025-00931-1. [PMID: 40085349 DOI: 10.1007/s40257-025-00931-1] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 02/09/2025] [Indexed: 03/16/2025]
42
Sutanto H, Adytia GJ, Fetarayani D. Hyper IgE Syndrome: Bridging the Gap Between Immunodeficiency, Atopy, and Allergic Diseases. Curr Allergy Asthma Rep 2025;25:17. [PMID: 40082265 DOI: 10.1007/s11882-025-01196-8] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 02/19/2025] [Indexed: 03/16/2025]
43
Calabrese L, Cinotti E, D'Onghia M, Cartocci A, Rubegni P, Maccari F, Boulard C, Reguiai Z, Becherel PA, Jacobzone C, Begon E, Fite C, Walls B, Liegeon AL, Parier J, Chaby G, Perrot JL. Effectiveness and Safety of Tralokinumab in Atopic Dermatitis: 1-year Results From a Real-world Multicentre Study. Acta Derm Venereol 2025;105:adv42275. [PMID: 40077977 DOI: 10.2340/actadv.v105.42275] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/16/2024] [Accepted: 01/08/2025] [Indexed: 03/14/2025]  Open
44
Soares GB, Orfali RL, Averbach BL, Yap QV, Yosipovitch G, Aoki V. Pruritus in atopic dermatitis: a cross-sectional study of adult patients from a tertiary university hospital in São Paulo, Brazil. An Bras Dermatol 2025:S0365-0596(25)00020-0. [PMID: 40074665 DOI: 10.1016/j.abd.2024.09.006] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/28/2024] [Revised: 09/05/2024] [Accepted: 09/10/2024] [Indexed: 03/14/2025]  Open
45
Schlosser AR, Nijman L, Schappin R, Nijsten TEC, Hijnen D. Long-term Outcomes of New Systemic Agents in Atopic Dermatitis: Drug Survival Analyses and Treatment Patterns in Daily Practice. Acta Derm Venereol 2025;105:adv41504. [PMID: 40059465 PMCID: PMC11904833 DOI: 10.2340/actadv.v105.41504] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/05/2024] [Accepted: 01/28/2025] [Indexed: 03/15/2025]  Open
46
Wang Y, Yin H, Li Z, Wu H, Wang Q, Chen X, Mao L, Wu Y, Wang S, Qin H, Gu C, Yao X, Li W. Blood Transcriptome Signature as Indicator and Predictor for Efficacy of Abrocitinib in Treatment of Atopic Dermatitis. J Invest Dermatol 2025:S0022-202X(25)00311-2. [PMID: 40058571 DOI: 10.1016/j.jid.2025.02.145] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/22/2024] [Revised: 01/30/2025] [Accepted: 02/21/2025] [Indexed: 03/28/2025]
47
Abdel-Mageed HM. Atopic dermatitis: a comprehensive updated review of this intriguing disease with futuristic insights. Inflammopharmacology 2025;33:1161-1187. [PMID: 39918744 PMCID: PMC11914373 DOI: 10.1007/s10787-025-01642-z] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/18/2024] [Accepted: 01/10/2025] [Indexed: 03/19/2025]
48
Mazgaj J, Kotewicz M, Jaworek A, Szepietowski JC. The future of topical JAK inhibitors in the treatment of atopic dermatitis. Expert Opin Pharmacother 2025;26:473-480. [PMID: 39924470 DOI: 10.1080/14656566.2025.2465869] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/02/2024] [Revised: 02/03/2025] [Accepted: 02/06/2025] [Indexed: 02/11/2025]
49
Chinthrajah RS, Sindher SB, Nadeau KC, Leflein JG, Spergel JM, Petroni DH, Jones SM, Casale TB, Wang J, Carr WW, Shreffler WG, Wood RA, Wambre E, Liu J, Akinlade B, Atanasio A, Orengo JM, Hamilton JD, Kamal MA, Hooper AT, Patel K, Laws E, Mannent LP, Adelman DC, Ratnayake A, Radin AR. Dupilumab as an Adjunct to Oral Immunotherapy in Pediatric Patients With Peanut Allergy. Allergy 2025;80:827-842. [PMID: 39673367 PMCID: PMC11891407 DOI: 10.1111/all.16420] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/13/2023] [Revised: 07/03/2024] [Accepted: 09/03/2024] [Indexed: 12/16/2024]
50
Torres T, Mendes-Bastos P, Cruz MJ, Duarte B, Filipe P, Lopes MJP, Gonçalo M. Interleukin-4 and Atopic Dermatitis: Why Does it Matter? A Narrative Review. Dermatol Ther (Heidelb) 2025;15:579-597. [PMID: 39930311 PMCID: PMC11909353 DOI: 10.1007/s13555-025-01352-y] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/10/2024] [Accepted: 01/28/2025] [Indexed: 03/15/2025]  Open
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