Case Report
Copyright ©The Author(s) 2016.
World J Clin Oncol. Apr 10, 2016; 7(2): 270-274
Published online Apr 10, 2016. doi: 10.5306/wjco.v7.i2.270
Table 1 Literature review of studies focusing on laparoscopy-related port-site metastasis
Ref.No. of patientsCohortType of surgeryResults
Chua et al[9], 201111027 from 17 studiesVarious cancers (colon, rectal, gynecological, gastric, liver, urological)Laparoscopic surgery or diagnostic surgery for malignant abdominal diseaseThe incidence of PSM is low (< 2%); in eight randomized trials comparing laparoscopy to open surgery for cancer, there was no statistical difference in the development of PSM or wound metastasis (none of these eight trials included gynaecological cancer patients)
Zivanovic et al[1], 20081694 (retrospective analysis of all laparoscopies in a 16-yr period)Various gynecological cancers (ovarian, perotineal, uterine, cervical)Laparoscopy in women with malignant diseaseLaparoscopy-related subcutaneous tumor implantation occurred in 20 cases (1.18%); only one case of “isolated” PSM was reported; subcutaneous tumor implantations usually occurred with carcinomatosis, with synchronous metastases to other sites; patients whose preceding laparoscopy was performed for advanced or recurrent abdominopelvic disease were more at risk for developing PSM; patients who developed PSM within 7 mo after laparoscopy had a median survival of 12 mo compared to 37 mo in patients who developed PSM > 7 mo after laparoscopy
Martínez et al[10], 20101216 (retrospective analysis of all laparoscopies)Uterine (921) and cervical (295) cancerLaparoscopy in women with malignant diseaseThe overall incidence of PSM was very low (0.4% per procedure) after a median follow-up of 49 mo; the median time to the development of PSM was 8 mo; patients with peritoneal carcinomatosis were most at risk for developing PSM
Ndofor et al[8], 2011181Various gynecological cancers (uterine, cervical, ovarian)Robotic surgery (DaVinci Surgical system) in women with malignant diseasePSM occurred in two cases (1.1%); there were no cases of isolated PSM
Heitz et al[5], 200966Ovarian cancerLaparoscopy followed by cytoreductive laparotomy with resection of port sitesPort site metastasis were present in 47% of patients; patients with ascites, higher tumor stage and peritoneal carcinomatosis were more at risk of developing PSM