Increased tensin 4 expression is related to the histological type of gastric cancer

Table 1 The characteristics of study group

Parameter	Number of cases
Age
< 60	29 (32.58%)
≥ 60	60 (67.42%)
Gender
Female	29 (32.58%)
Male	60 (67.42%)
Tumor diameter
< 5 cm	18 (20.22%)
≥ 5 cm	71 (79.78%)
Tumor localization
Upper 1/3	17 (19.10%)
Middle1/3	33 (37.08%)
Lower 1/3	16 (17.98%)
Whole stomach	23 (25.84%)
Histological type
Adenocarcinoma	54 (60.67%)
Adenocarcinoma mucinosum	35 (39.33%)
Histological differentiation
Moderately differentiated	25 (28.09%)
Poorly differentiated	35 (39.33%)
Non differentiated	29 (32.58%)
Depth of invasion
T1	6 (6.74%)
T2	7 (7.87%)
T3	66 (74.16%)
T4	10 (11.23%)
Lymph node metastasis
Absent	17 (19.10%)
Present	72 (80.90%)
Distant metastasis
Absent	61 (68.54%)
Present	28 (31.46%)
Blood vessel infiltration
Absent	48 (84.21%)
Present	9 (15.79%)
Lymphatic vessel infiltration
Absent	21 (31.82%)
Present	45 (68.18%)
Perineural infiltration
Absent	28 (34.15%)
Present	54 (65.85%)
Peritumoral inflammation
Absent	42 (50.00%)
Present	42 (50.00%)
Desmoplasia
Small	55 (66.27%)
Large	28 (33.73%)
Helicobacter pylori infection
Absent	61 (73.49%)
Present	22 (26.51%)
Lauren’s classification
Intestinal	44 (55.00%)
Diffuse	36 (45.00%)

Table 2 Correlation between clinical pathological parameters and tensin 4 protein expression

Parameter	Expression of tensin 4 protein		aP value
	Negative	Positive
Age			0.666
< 60	14 (48.28%)	15 (51.72%)
≥ 60	26 (43.33%)	34 (56.67%)
Gender			0.182
Female	16 (55.17%)	13 (44.83%)
Male	24 (40.00%)	36 (60.00%)
Tumor diameter			0.040
< 5 cm	12 (66.67%)	6 (33.33%)
≥ 5 cm	28 (39.44%)	43 (60.56%)
Tumor localization			0.081
Upper 1/3	10 (58.82%)	7 (41.18%)
Middle1/3	9 (27.27%)	24 (72.73%)
Lower 1/3	9 (56.25%)	7 (43.75%)
Whole stomach	12 (52.17%)	11 (47.83%)
Histological type			0.023
Adenocarcinoma	19 (35.19%)	35 (64.81%)
Adenocarcinoma mucinosum	21 (60.00%)	14 (40.00%)
Histological differentiation			0.002 (< 0.001)
Moderately differentiated	5 (20.00%)	20 (80.00%)
Poorly differentiated	15 (42.86%)	20 (57.14%)
Non differentiated	20 (68.97%)	9 (31.03%)
Depth of invasion			0.208
T1	5 (83.33%)	1 (16.67%)
T2	2 (28.57%)	5 (71.43%)
T3	28 (42.42%)	38 (57.58%)
T4	5 (50.00%)	5 (50.00%)
Lymph node metastasis			0.071
Absent	11 (64.71%)	6 (35.29%)
Present	29 (40.28%)	43 (59.72%)
Distant metastasis			0.794
Absent	28 (45.90%)	33 (54.10%)
Present	12 (42.86%)	16 (57.14%)
Blood vessel infiltration			0.980
Absent	21 (43.75%)	27 (56.25%)
Present	4 (44.44%)	5 (55.56%)
Lymphatic vessel infiltration			0.358
Absent	10 (47.62%)	11 (52.38%)
Present	16 (35.56%)	29 (64.44%)
Perineural infiltration			0.628
Absent	13 (46.43%)	15 (53.57%)
Present	22 (40.74%)	32 (59.26%)
Peritumoral inflammation			0.453
Absent	19 (46.34%)	22 (53.66%)
Present	16 (38.10%)	26 (61.90%)
Desmoplasia			0.710
Small	24 (43.64%)	31 (56.36%)
Large	11 (39.29%)	17 (60.71%)
Helicobacter pylori infection			0.824
Absent	26 (42.62%)	35 (57.38%)
Present	10 (45.45%)	12 (54.55%)
Lauren’s classification			0.020
Intestinal	13 (29.55%)	31 (70.45%)
Diffuse	20 (55.56%)	16 (44.44%)

^aIn bracket is P value before Dunn’s multiple comparison post hoc test.