Clinical and Translational Research
Copyright ©The Author(s) 2024.
World J Clin Oncol. Jan 24, 2024; 15(1): 32-44
Published online Jan 24, 2024. doi: 10.5306/wjco.v15.i1.32
Figure 4
Figure 4 Scinderin silencing promotes F-actin depolymerization and inhibits RhoA/focal adhesion kinase signaling of glioma cells. A: F-actin cytoskeleton in glioma cells was visualized using Phalloidin staining (green). Scinderin (SCIN) led to a diminution of ruffles and pseudopods on the cell surface; B: Knockdown of SCIN reduced the expression of p-cofilin, RhoA, p-focal adhesion kinase, and Talin, as demonstrated by western blotting. aP < 0.05, bP < 0.01, cP < 0.001.