Copyright ©The Author(s) 2019.
World J Clin Oncol. Jan 10, 2019; 10(1): 1-13
Published online Jan 10, 2019. doi: 10.5306/wjco.v10.i1.1
Table 5 Submandibular gland transfer: Salivary function, quality of life, toxicity
AuthorSalivary functionQuality of lifeToxicity
Zhang et al[31], 2004Transfer 1.39 g and 1.6 g saliva vs 0.66 and 0.68 g control at 1 yr and 5 yr, respectively. Significantly higher submandibular gland secretion in transfer group at 5 yr (radionuclide scintigraphy).Significantly improved speech, chewing, swallowing, changes in eating habits, nighttime xero, need to wake up to drink frequently, sleep quality in transfer groupNo surgical death or complications occurred in transfer group
Rieger et al[51], 2012NANANot reported
Liu et al[50], 2011Significantly better trapping and excretion (scintigraphy) in transfer group at 5 yr; Significantly higher mean weight of unstimulated saliva in transfer group at 5 yrTransfer group improved significantly vs control in dry mouth, night rest, drink to speech, drink to eat, water intake, change in feeding pattern, tooth decay, and visual analogue scaleNo major complications of surgery (one pt taken back 2 yr later for removal of wire used to mark borders of transferred gland due to pain)
Seikaly et al[49], 2004Significantly higher stimulated and unstimulated saliva in transfer group at 16 moNANo surgical complications from submandibular transfer
Jha et al[48], 2003stimulated and unstimulated saliva decrease gradually, then increase at 16 mo (graphical)NANo surgical complications