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World J Clin Oncol. Nov 10, 2010; 1(1): 12-17
Published online Nov 10, 2010. doi: 10.5306/wjco.v1.i1.12
Figure 1
Figure 1 Oxidation of guanine (G) and deprotonation of its radical cation (G•+). The pKa-value of G is drastically lowered upon one-electron oxidation and subsequent deprotonation of the N1 proton changes it from a hydrogen bond donor to a hydrogen bond acceptor. The number of atoms constituting G is shown. Drib: 2’-deoxyribose moiety.