Copyright ©The Author(s) 2016.
World J Clin Oncol. Feb 10, 2016; 7(1): 122-130
Published online Feb 10, 2016. doi: 10.5306/wjco.v7.i1.122
Figure 1
Figure 1 Metabolic reprogramming in malignant cells. Most malignant cells present with increased aerobic glycolysis, fatty acid synthesis and glutaminolysis. The pink circles in the figure show the possible metabolic targets of enzymes or receptors. GLUT: Glucose transporter proteins; HK: Hexokinase; PKM: Pyruvate kinase M; LDH: Lactate dehydrogenase; FASN: Fatty acid synthase; ACS: Acetyl-CoA synthase; IDH: Isocitrate dehydrogenase; GLS: Glutaminase.