Diagnosis and treatment of metachronous multiple primary carcinoma: A case report and review of literature

Figure 1 Invasive ductal carcinoma of the breast. A: Immunohistochemistry revealed ER (90%), E-cadherin (+), PR (5%), P120 (membrane+), indicating a diagnosis of invasive ductal carcinoma of the breast; B: Breast ultrasound showed a solid mass in the left breast with a diameter of 2.4 cm.

Figure 2 Metachronous diffuse large B-cell lymphoma. A-C: Computed tomography showed multiple enlarged lymph nodes adjacent to the abdominal aorta (A) and bilateral iliac vessels (B) and abdominal cavity (C); D: Immunohistochemical results showed that CD20 (+), Ki-67 (80%). These results suggested a diagnosis of diffuse large B-cell lymphoma.

Figure 3 Treatment outcome of diffuse large B-cell lymphoma. A-E: Lymph nodes adjacent to the abdominal aorta (A) and bilateral iliac vessels (B) and abdominal cavity (C-E) were significantly reduced compared to before treatment; F and G: Multiple lymph node shadows can be seen near the abdominal aorta, bilateral iliac vessels, and abdominal cavity, partially fused into clusters; H-J: The abdominal lymph nodes were significantly shrunk and decreased compared to before treatment; K-O: The latest re-examination result shows that lymph nodes adjacent to the abdominal aorta (K) and bilateral iliac vessels (L) and abdominal cavity (M-O) were significantly reduced.