Unusual breast metastasis of gastrointestinal stromal tumor: A case report and literature review

Figure 1 Breast magnetic resonance imaging. Heterogeneous lesion 47 mm (orange arrows) on the border of the upper quadrants of the right breast with central zone of necrosis and peripheral vascularization. A: Axial; B: Frontal.

Figure 2 Positron emission tomography-computed tomography. A: Computed tomography (CT) on September 2020; B: СТ on February 2021 demonstrated progression in the right breast lesion (orange arrows), size increased from 39 mm to 48 mm.

Figure 3 Macroscopic examination. A, B: Macroscopical size 50 mm, thick fibrous capsule.

Figure 4 Microscopic examination. A: Histology, original magnification ×200, hematoxylin-eosin stain; B: Immunohistochemistry original magnification ×200, CD34 positive stain; C: Immunohistochemistry ×200, CD117 positive stain, D: Immunohistochemistry original magnification×200, DOG-1 positive stain.

Figure 5 Treatment timeline.