Field of Vision
Copyright ©The Author(s) 2022.
World J Clin Oncol. Aug 24, 2022; 13(8): 663-674
Published online Aug 24, 2022. doi: 10.5306/wjco.v13.i8.663
Figure 1
Figure 1 Selected combinations with cancer treatment vaccines: Immune checkpoint inhibitors, radiotherapy, metronomic chemotherapy, and metformin. aEspecially mRNA cancer vaccines: cell-free, rapid production, versatile and inherent adjuvant properties outperforming pathogen vaccines repurposed for oncology. Even balancing innate and adaptive immunities is feasible with mRNA. bMetformin’s long standing safety track record, ready availability and eminent affordability may enable an ideal combination with mRNA cancer vaccines. ICI: Immune checkpoint inhibitors; mChT: Metronomic chemotherapy; RT: Radiotherapy.