Hepatobiliary manifestations in children with inflammatory bowel disease: A single-center experience in a low/middle income country

Table 1 The presenting symptoms of children with inflammatory bowel disease in the study group (n = 48)

Complaint	n	Percentage
Abdominal pain	47	97.9
Diarrhoea	43	89.6
Tenesmus	36	75
Bleeding per rectum	35	72.9
Chronic fatigue	19	39.6
Weight loss	13	27.1
Low grade fever	13	27.1

Table 2 The liver biochemical profile of children with inflammatory bowel disease in the study group

Parameter	Result	Range
ALT in median (IQR) (up to 45 U/L)	16.5 (13-24.8)	8-184
AST in median (IQR) (up to 75 U/L)	27 (20.5-34)	6-226
TB in median (IQR) (up to 1.4 mg/dL)	0.4 (0.3-0.5)	0.1-3.4
DB in median (IQR) (up to 1.4 mg/dL)	0.1 (0.1-0.1)	0-1.7
ALP in median (IQR) (up to 640 U/L)	161 (88-239)	50-439
GGT in median (IQR) (up to 50 U/L)	15 (12.3-19.8)	8-331
Albumin in mean ± SD (3.5-4.5 g/dL)	3.75 ± 0.78	1.3-5.3
PT in mean ± SD (s)	13.1 ± 0.59	11.7-14.8
PC in mean ± SD	92.8 ± 7.41	76-100
INR in mean ± SD	1.02 ± 0.05	1-1.2

ALT: Alanine aminotransferase; AST: aspartate aminotransferase; ALP: Alkaline phosphatase; DB: Direct bilirubin; IQR: interquartile range; GGT: Gamma-Glutamyl transferase; INR: International normalized ratio; PC: Prothrombin concentration; PT: Prothrombin time; TB: Total bilirubin.