Case Control Study
Copyright ©The Author(s) 2020.
World J Gastrointest Pharmacol Ther. Aug 8, 2020; 11(3): 40-47
Published online Aug 8, 2020. doi: 10.4292/wjgpt.v11.i3.40
Table 1 Characteristics of study population
FactorControlsSBAPHGGAVEControls vs cases
Number1510118
mean age (range)49 (20-74)68 (53-79)60 (38-81)68 (58-85)P < 0.0005
Male gender, n (%)7 (47)5 (50)3 (27%)5 (63)NS
mean haemoglobin, g/dL12.511.411.211.5NS
Anaemia, n (%)11 (20)4 (40)6 (75)3/5 (60)P < 0.05
Table 2 Levels of serum angiogenic factors according to group
SBAPHGGAVEControl
Ang-1 (ng/mL), mean (range)35696 (12466-54338)23111 (1950-72445)30753 (9773-72609)53115 (28624-82066)
P value vs controls0.010.00030.01
Ang-2 (ng/mL), mean (range)2803 (125-13141)4298 (1299-8702)4232 (1253-6081)1899 (742-3693)
P value vs controls0.40.00080.003
VEGF (ng/mL), mean (range)443 (273-964)316 (51-600)435 (288-637)421 (250-678)
P value vs controls0.80.080.8
Ang-1/Ang-2 ratios by group135728
Median Ang-1/Ang-2 ratios828
P value vs controls0.001