Hepatobiliary manifestations in children with inflammatory bowel disease: A single-center experience in a low/middle income country

Figure 1 Abdominal ultrasound of a patient with inflammatory bowel disease showing increased liver echogenicity.

Figure 2 Magnetic resonance cholangiopancreatography of a patient with inflammatory bowel disease and primary sclerosing cholangitis showing dilatation of the intra- and extra-hepatic biliary tree with multiple strictures (arrows).

Figure 3 Histopathological findings of a liver biopsy specimen from a patient with inflammatory bowel disease showing the features of primary sclerosing cholangitis. A: Diffuse bile ductular proliferation "Onion skin" fibrosis around affected ducts, concentric collagen fibre deposition; B: Same findings by Masson's trichrome stain which imparts a blue color to type 1 collagen against a red background of hepatocytes; C: Aggression of inflammatory cells towards the biliary epithelium and the portal area is markedly expanded with lymphoplasmacytic inflammatory cellular infiltrate (all photos H&E, Original magnification × 400).