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For: Etienne-Mesmin L, Chassaing B, Gewirtz AT. Tryptophan: A gut microbiota-derived metabolites regulating inflammation. World J Gastrointest Pharmacol Ther 2017; 8(1): 7-9 [PMID: 28217370 DOI: 10.4292/wjgpt.v8.i1.7]
URL: https://www.wjgnet.com/2150-5349/full/v8/i1/7.htm
Number Citing Articles
1
Jingyuan Tao, Guangmang Liu, Ke Gu, Gang Jia, Hua Zhao, Xiaoling Chen, Gang Tian, Jingyi Cai, Jing Wang. Tryptophan alleviates intestinal damage through regulating necroptosis and TLR4/NOD signaling pathways in pigs after lipopolysaccharide challenge. Animal Biotechnology 2023; 34(9) doi: 10.1080/10495398.2023.2213278
2
Qixing Nie, Haihong Chen, Jielun Hu, He Gao, Linlin Fan, Zhimin Long, Shaoping Nie. Arabinoxylan Attenuates Type 2 Diabetes by Improvement of Carbohydrate, Lipid, and Amino Acid Metabolism. Molecular Nutrition & Food Research 2018; 62(20) doi: 10.1002/mnfr.201800222
3
Haoyan Zhu, Xingbin Yang, Yan Zhao. Recent Advances in Current Uptake Situation, Metabolic and Nutritional Characteristics, Health, and Safety of Dietary Tryptophan. Journal of Agricultural and Food Chemistry 2024; 72(13) doi: 10.1021/acs.jafc.3c06419
4
Tianlai Lin, Qiang Liu, Mouying Liu, Xizhe Chen, Ling Huang, Sican Wei, Hongling Zhang. Sunflower oil-loaded lycopene protects intestinal barrier integrity following traumatic brain injury. Journal of Molecular Histology 2026; 57(5) doi: 10.1007/s10735-026-10980-3
5
Jesús K. Yamamoto-Furusho, Gabriela Fonseca-Camarillo, Janette Furuzawa-Carballeda, Andrea Sarmiento-Aguilar, Rafael Barreto-Zuñiga, Braulio Martínez-Benitez, Montserrat A. Lara-Velazquez. Caspase recruitment domain (CARD) family (CARD9, CARD10, CARD11, CARD14 and CARD15) are increased during active inflammation in patients with inflammatory bowel disease. Journal of Inflammation 2018; 15(1) doi: 10.1186/s12950-018-0189-4
6
Katharina Hopp, Emily K. Kleczko, Berenice Y. Gitomer, Michel Chonchol, Jost Klawitter, Uwe Christians, Jelena Klawitter. Metabolic reprogramming in a slowly developing orthologous model of polycystic kidney disease. American Journal of Physiology-Renal Physiology 2022; 322(3) doi: 10.1152/ajprenal.00262.2021
7
Catherine Leyh, Jason D. Coombes, Hartmut H. Schmidt, Ali Canbay, Paul P. Manka, Jan Best. MASLD-Related HCC—Update on Pathogenesis and Current Treatment Options. Journal of Personalized Medicine 2024; 14(4) doi: 10.3390/jpm14040370
8
Luc Colas, Emmanuel F. Mongodin, Emmanuel Montassier, Mélanie Chesneau, Pierrick Guerif, Lauren Hittle, Magali Giral, Jonathan S. Bromberg, Sophie Brouard. Unique and specific Proteobacteria diversity in urinary microbiota of tolerant kidney transplanted recipients. American Journal of Transplantation 2020; 20(1) doi: 10.1111/ajt.15549
9
Andrew J. Forgie, Kelsea M. Drall, Stephane L. Bourque, Catherine J. Field, Anita L. Kozyrskyj, Benjamin P. Willing. The impact of maternal and early life malnutrition on health: a diet-microbe perspective. BMC Medicine 2020; 18(1) doi: 10.1186/s12916-020-01584-z
10
Pooja Rani Mina. Gut Microbiota: A Future Clinical Magic Bullet to Manifest Pathogenic Disease in the Current Future. Journal of Pure and Applied Microbiology 2023; 17(1) doi: 10.22207/JPAM.17.1.43
11
Zhiwei Yan, Zhuangzhuang Liu, Yong Ma, Zhao Yang, Gang Liu, Jun Fang. Effects of Lactobacillus plantarum and Weissella viridescens on the Gut Microbiota and Serum Metabolites of Mice with Antibiotic-Associated Diarrhea. Nutrients 2023; 15(21) doi: 10.3390/nu15214603
12
Nan Zhang, Jun Liu, Zhiyun Chen, Ning Chen, Fangyan Gu, Qiushui He. Integrated Analysis of the Alterations in Gut Microbiota and Metabolites of Mice Induced After Long-Term Intervention With Different Antibiotics. Frontiers in Microbiology 2022; 13 doi: 10.3389/fmicb.2022.832915
13
Fang He, Chenlu Wu, Pan Li, Nengzhang Li, Dong Zhang, Quoqiang Zhu, Wenkai Ren, Yuanyi Peng. Functions and Signaling Pathways of Amino Acids in Intestinal Inflammation. BioMed Research International 2018; 2018 doi: 10.1155/2018/9171905
14
Ewa Dudzińska, Kinga Szymona, Renata Kloc, Paulina Gil-Kulik, Tomasz Kocki, Małgorzata Świstowska, Jacek Bogucki, Janusz Kocki, Ewa M. Urbanska. Increased expression of kynurenine aminotransferases mRNA in lymphocytes of patients with inflammatory bowel disease. Therapeutic Advances in Gastroenterology 2019; 12 doi: 10.1177/1756284819881304
15
Mihaela Stoyanova, Vera Gledacheva, Stoyanka Nikolova. Gut–Brain–Microbiota Axis in Irritable Bowel Syndrome: A Narrative Review of Pathophysiology and Current Approaches. Applied Sciences 2025; 15(12) doi: 10.3390/app15126441
16
17
Arnold Berstad, Olav Hauso, Ketil Berstad, Johanna E.R. Berstad. From IBS to ME – The dysbiotic march hypothesis. Medical Hypotheses 2020; 140 doi: 10.1016/j.mehy.2020.109648
18
Pritam Bardhan, Xue Mei, Ngoc Khanh Lai, Blair Mell, Ramakumar Tummala, Sachin Aryal, Ishan Manandhar, Hyeongu Hwang, Tania Akter Jhuma, Rohit Reddy Atluri, Jun Kyoung, Ying Li, Bina Joe, Hong-Bao Li, Tao Yang. Salt-Responsive Gut Microbiota Induces Sex-Specific Blood Pressure Changes. Circulation Research 2024; 135(12) doi: 10.1161/CIRCRESAHA.124.325056
19
Lucille C. Rankin, Katherine A. Kaiser, Kenia de los Santos-Alexis, Heekuk Park, Anne-Catrin Uhlemann, Daniel H.D. Gray, Nicholas Arpaia. Dietary tryptophan deficiency promotes gut RORγt+ Treg cells at the expense of Gata3+ Treg cells and alters commensal microbiota metabolism. Cell Reports 2023; 42(3) doi: 10.1016/j.celrep.2023.112135
20
Hao Cheng, Juan Liu, Dandan Zhang, Jing Wang, Yuzhu Tan, Wuwen Feng, Cheng Peng. Ginsenoside Rg1 Alleviates Acute Ulcerative Colitis by Modulating Gut Microbiota and Microbial Tryptophan Metabolism. Frontiers in Immunology 2022; 13 doi: 10.3389/fimmu.2022.817600
21
Jiří Hrdý, Aurélie Couturier-Maillard, Denise Boutillier, Carmen Lapadatescu, Philippe Blanc, Jan Procházka, Bruno Pot, Bernhard Ryffel, Corinne Grangette, Mathias Chamaillard. Oral supplementation with selected Lactobacillus acidophilus triggers IL-17-dependent innate defense response, activation of innate lymphoid cells type 3 and improves colitis. Scientific Reports 2022; 12(1) doi: 10.1038/s41598-022-21643-0
22
Postbiotics: An alternative and innovative intervention for the therapy of inflammatory bowel disease. Microbiological Research 2024; 279 doi: 10.1016/j.micres.2023.127550
23
Maria C. Opazo, Elizabeth M. Ortega-Rocha, Irenice Coronado-Arrázola, Laura C. Bonifaz, Helene Boudin, Michel Neunlist, Susan M. Bueno, Alexis M. Kalergis, Claudia A. Riedel. Intestinal Microbiota Influences Non-intestinal Related Autoimmune Diseases. Frontiers in Microbiology 2018; 9 doi: 10.3389/fmicb.2018.00432
24
Guangmang Liu, Ke Gu, Fang Wang, Gang Jia, Hua Zhao, Xiaoling Chen, Caimei Wu, Ruinan Zhang, Gang Tian, Jingyi Cai, Jiayong Tang, Jing Wang. Tryptophan Ameliorates Barrier Integrity and Alleviates the Inflammatory Response to Enterotoxigenic Escherichia coli K88 Through the CaSR/Rac1/PLC-γ1 Signaling Pathway in Porcine Intestinal Epithelial Cells. Frontiers in Immunology 2021; 12 doi: 10.3389/fimmu.2021.748497
25
Lie Zheng, Xin-Li Wen, Sheng-Lei Duan. Role of metabolites derived from gut microbiota in inflammatory bowel disease. World Journal of Clinical Cases 2022; 10(9) doi: 10.12998/wjcc.v10.i9.2658
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26
Xiongzhuo Tang, Wan Li, Jing Gao, Qian Jiang, Shenglan Hu, Hao Xiao, Jing Wang, Ming Qi, Leli Wang, Lang Huang, Junhao Deng, Zian Yuan, Yuezhou Yao, Feiyue Chen, Qian Xie, Mengdi Yao, Qing-Wen Gui, Yulong Yin. Tryptophan in Animal Nutrition and Human Health. 2024;  doi: 10.1007/978-981-97-4719-1_2
27
Yulan Liu, Xiuying Wang, Chien-An Hu. Therapeutic Potential of Amino Acids in Inflammatory Bowel Disease. Nutrients 2017; 9(9) doi: 10.3390/nu9090920
28
Judith B. Ngere, Kourosh H. Ebrahimi, Rachel Williams, Elisabete Pires, John Walsby-Tickle, James S. O. McCullagh. Ion-Exchange Chromatography Coupled to Mass Spectrometry in Life Science, Environmental, and Medical Research. Analytical Chemistry 2023; 95(1) doi: 10.1021/acs.analchem.2c04298
29
Heidi Hall. Can We Influence Gut Health to Reduce the Need for Antimicrobials in Pig Production?. Animal Science Cases 2023;  doi: 10.1079/animalsciencecases.2023.0001
30
Joanna Kałużna-Czaplińska, Paulina Gątarek, Max Stanley Chartrand, Maryam Dadar, Geir Bjørklund. Is there a relationship between intestinal microbiota, dietary compounds, and obesity?. Trends in Food Science & Technology 2017; 70 doi: 10.1016/j.tifs.2017.10.010
31
Taif Shah, Zulqarnain Baloch, Zahir Shah, Xiuming Cui, Xueshan Xia. The Intestinal Microbiota: Impacts of Antibiotics Therapy, Colonization Resistance, and Diseases. International Journal of Molecular Sciences 2021; 22(12) doi: 10.3390/ijms22126597
32
Sheel Patel, Fares Kasem, Dylan Flaherty, Ashutosh Barve. HCC in MASLD and ALD: Biochemical Pathways, Epidemiology, Diagnosis, and Treatment. BioChem 2025; 5(3) doi: 10.3390/biochem5030019
33
Xueyan Ding, Peng Bin, Wenwen Wu, Yajie Chang, Guoqiang Zhu. Tryptophan Metabolism, Regulatory T Cells, and Inflammatory Bowel Disease: A Mini Review. Mediators of Inflammation 2020; 2020 doi: 10.1155/2020/9706140
34
Nurhan Unusan. Essential oils and microbiota: Implications for diet and weight control. Trends in Food Science & Technology 2020; 104 doi: 10.1016/j.tifs.2020.07.014
35
Hong-Yu Cheng, Meng-Xia Ning, De-Kun Chen, Wen-Tao Ma. Interactions Between the Gut Microbiota and the Host Innate Immune Response Against Pathogens. Frontiers in Immunology 2019; 10 doi: 10.3389/fimmu.2019.00607
36
Rahman Ladak, Dana Philpott. Mice, Models, Microbiota: How Can We More Accurately Reflect Human Disease?. Journal of Undergraduate Life Sciences 2021; 15(1) doi: 10.33137/juls.v15i1.36811
37
Qing Li, Yiran You, Yupeng Zeng, Xu Wang, Zhijun Pan, Juan Pang, Qian Chen, Yuqing Zhou, Yufeng Jin, Yan Yang, Wenhua Ling. Associations between plasma tryptophan and indole-3-propionic acid levels and mortality in patients with coronary artery disease. The American Journal of Clinical Nutrition 2022; 116(4) doi: 10.1093/ajcn/nqac170
38
Ewa Dudzińska. The Recent Topics in Genetic Polymorphisms. 2020;  doi: 10.5772/intechopen.92051
39
Junfeng Zou, Chen Liu, Shu Jiang, Dawei Qian, Jinao Duan, Anthony R. Richardson. Cross Talk between Gut Microbiota and Intestinal Mucosal Immunity in the Development of Ulcerative Colitis. Infection and Immunity 2021; 89(9) doi: 10.1128/IAI.00014-21
40
Jing Gao, Kang Xu, Hongnan Liu, Gang Liu, Miaomiao Bai, Can Peng, Tiejun Li, Yulong Yin. Impact of the Gut Microbiota on Intestinal Immunity Mediated by Tryptophan Metabolism. Frontiers in Cellular and Infection Microbiology 2018; 8 doi: 10.3389/fcimb.2018.00013
41
Meng-Xia Wang, Li Lin, Yong-Da Chen, Yu-Ping Zhong, Yi-Xuan Lin, Pei Li, Xing Tian, Bo Han, Zhi-Yong Xie, Qiong-Feng Liao. Evodiamine has therapeutic efficacy in ulcerative colitis by increasing Lactobacillus acidophilus levels and acetate production. Pharmacological Research 2020; 159 doi: 10.1016/j.phrs.2020.104978
42
Olga N. Ilinskaya, Vera V. Ulyanova, Dina R. Yarullina, Ilgiz G. Gataullin. Secretome of Intestinal Bacilli: A Natural Guard against Pathologies. Frontiers in Microbiology 2017; 8 doi: 10.3389/fmicb.2017.01666
43
Wen Zeng, Dong He, Yifan Xing, Junyu Liu, Nan Su, Chong Zhang, Yi Wang, Xinhui Xing. Internal connections between dietary intake and gut microbiota homeostasis in disease progression of ulcerative colitis: a review. Food Science and Human Wellness 2021; 10(2) doi: 10.1016/j.fshw.2021.02.016
44
Ling Zhao, Hai-tao Xiao, Huai-xue Mu, Tao Huang, Ze-si Lin, Linda Zhong, Guang-zhi Zeng, Bao-min Fan, Cheng-yuan Lin, Zhao-xiang Bian. Magnolol, a Natural Polyphenol, Attenuates Dextran Sulfate Sodium-Induced Colitis in Mice. Molecules 2017; 22(7) doi: 10.3390/molecules22071218
45
Shuqi Jia, Songyi Lin, Qiaozhen Liu, Shuya Wang, Xiuhan Chen, Na Sun. Unveiling the impact of dietary components on tropomyosin-induced anaphylaxis: Analysis from the perspective of intestinal barrier. Food Bioscience 2024; 62 doi: 10.1016/j.fbio.2024.105254
46
Zhifeng Wu, Fan Zhang, Yuan Wang, Chunjiang Liu, Zhaokun Sun, Xiaoqi Tang, Liming Tang, Yang Shi. Revealing potential interfering genes between abdominal aortic aneurysm and periodontitis through machine learning and bioinformatics analysis. PLOS One 2025; 20(8) doi: 10.1371/journal.pone.0329592
47
Hong-Li Li, Lan Lu, Xiao-Shuang Wang, Li-Yue Qin, Ping Wang, Shui-Ping Qiu, Hui Wu, Fei Huang, Bei-Bei Zhang, Hai-Lian Shi, Xiao-Jun Wu. Alteration of Gut Microbiota and Inflammatory Cytokine/Chemokine Profiles in 5-Fluorouracil Induced Intestinal Mucositis. Frontiers in Cellular and Infection Microbiology 2017; 7 doi: 10.3389/fcimb.2017.00455
48
Darren D. O’Rielly, Guangju Zhai, Proton Rahman. Expression and Metabolomic Profiling in Axial Spondyloarthritis. Current Rheumatology Reports 2018; 20(8) doi: 10.1007/s11926-018-0756-y
49
Lie Zheng, Xin-Li Wen, Sheng-Lei Duan. Role of metabolites derived from gut microbiota in inflammatory bowel disease. World Journal of Clinical Cases 2022; 10(9): 2660-2677 doi: 10.12998/wjcc.v10.i9.2660
50
Aleksandar Acovic, Bojana Simovic Markovic, Marina Gazdic, Aleksandar Arsenijevic, Nemanja Jovicic, Nevena Gajovic, Marina Jovanovic, Natasa Zdravkovic, Tatjana Kanjevac, C. Randall Harrell, Crissy Fellabaum, Zana Dolicanin, Valentin Djonov, Nebojsa Arsenijevic, Miodrag L. Lukic, Vladislav Volarevic. Indoleamine 2,3-dioxygenase-dependent expansion of T-regulatory cells maintains mucosal healing in ulcerative colitis. Therapeutic Advances in Gastroenterology 2018; 11 doi: 10.1177/1756284818793558
51
Jinliang Hou, Jianguo Xiang, Deliang Li, Xinhua Liu, Wangcheng Pan. Gut microbial response to host metabolic phenotypes. Frontiers in Nutrition 2022; 9 doi: 10.3389/fnut.2022.1019430
52
Peter Hoffmann, David Lamerz, Petra Hill, Marietta Kirchner, Annika Gauss. Gene Polymorphisms of NOD2, IL23R, PTPN2 and ATG16L1 in Patients with Crohn’s Disease: On the Way to Personalized Medicine?. Genes 2021; 12(6) doi: 10.3390/genes12060866
53
Jing Ma, Pengyan Tong, Kang Yang, Yining Jia, Zhen Liu, Mengya Zhao, Jing Liu, Fangyu Long. Lactiplantibacillus plantarum Mediated Tryptophan Metabolism to Alleviate Tropomyosin-induced Food Allergy. Probiotics and Antimicrobial Proteins 2026; 18(7) doi: 10.1007/s12602-026-11039-1
54
Vladislav Volarevic, Natasa Zdravkovic, Carl Randall Harrell, Nebojsa Arsenijevic, Crissy Fellabaum, Valentin Djonov, Miodrag L. Lukic, Bojana Simovic Markovic. Galectin-3 Regulates Indoleamine-2,3-dioxygenase-Dependent Cross-Talk between Colon-Infiltrating Dendritic Cells and T Regulatory Cells and May Represent a Valuable Biomarker for Monitoring the Progression of Ulcerative Colitis. Cells 2019; 8(7) doi: 10.3390/cells8070709
55
I. V. Nikolayeva, V. M. Sheibak, A. B. Astrowskaja, S. A. Astrautsova. The effect of acetaminophen on the structural and functional state of the large intestine and intestinal microflora. Health and Ecology Issues 2023; 20(2) doi: 10.51523/2708-6011.2023-20-2-11
56
James R Templeman, Emma Thornton, Cara Cargo-Froom, Eli J Squires, Kelly S Swanson, Anna K Shoveller. Effects of incremental exercise and dietary tryptophan supplementation on the amino acid metabolism, serotonin status, stool quality, fecal metabolites, and body composition of mid-distance training sled dogs. Journal of Animal Science 2020; 98(5) doi: 10.1093/jas/skaa128
57
Himel Mallick, Eric A. Franzosa, Lauren J. Mclver, Soumya Banerjee, Alexandra Sirota-Madi, Aleksandar D. Kostic, Clary B. Clish, Hera Vlamakis, Ramnik J. Xavier, Curtis Huttenhower. Predictive metabolomic profiling of microbial communities using amplicon or metagenomic sequences. Nature Communications 2019; 10(1) doi: 10.1038/s41467-019-10927-1
58
Maurizio Salvadori, Aris Tsalouchos. Microbiota, renal disease and renal transplantation. World Journal of Transplantation 2021; 11(3): 16-36 doi: 10.5500/wjt.v11.i3.16
59
Irene Mignini, Maria Elena Ainora, Silvino Di Francesco, Linda Galasso, Antonio Gasbarrini, Maria Assunta Zocco. Tumorigenesis in Inflammatory Bowel Disease: Microbiota-Environment Interconnections. Cancers 2023; 15(12) doi: 10.3390/cancers15123200
60
Nazmul MHM, Vetriselvan Subramaniyan, Srikumar Chakravarthi, Thidar Aung, Sergey Gupalo, Wana Hla Shwe, Sutha Devaraj, Phone Myint Htoo, Myat Myo Naing, Lei Lei Win, Aye Aye Tun, Tahmina Afrose Keya, Srikanth Jeyabalan, Chetan Ashok, Mukesh Kumar. Obesity-driven gut-immune-brain axis dysregulation: Emerging molecular targets and biomaterial-based interventions. Obesity Medicine 2026; 63 doi: 10.1016/j.obmed.2026.100731
61
Pengkui Xia, Tao Hou, Hong Jin, Yaqi Meng, Jing Li, Fuchao Zhan, Fang Geng, Bin Li. A critical review on inflammatory bowel diseases risk factors, dietary nutrients regulation and protective pathways based on gut microbiota during recent 5 years. Critical Reviews in Food Science and Nutrition 2024; 64(24) doi: 10.1080/10408398.2023.2204147
62
Rong Li, Xue Huang, Lu Yang, Xiao Liang, Wenjun Huang, Keng Po Lai, Liming Zhou. Integrated Analysis Reveals the Targets and Mechanisms in Immunosuppressive Effect of Mesalazine on Ulcerative Colitis. Frontiers in Nutrition 2022; 9 doi: 10.3389/fnut.2022.867692