Basic Study
Copyright ©The Author(s) 2017.
World J Gastrointest Pathophysiol. May 15, 2017; 8(2): 59-66
Published online May 15, 2017. doi: 10.4291/wjgp.v8.i2.59
Table 1 Short-circuit current and oxygen consumption of the isolated mucosa of rat sigmoid colon
TreatmentnIsc μmol × cm-2 × h-1Total QO2 μmol × cm-2 × h-1Serosal QO2 μmol × cm-2 × h-1Mucosal QO2 μmol × cm-2 × h-1
None203.33 ± 0.212.79 ± 0.061.52 ± 0.041.28 ± 0.08b
Low Cl60.66 ± 0.072.56 ± 0.131.41 ± 0.081.14 ± 0.06d
Bum + DPC60.63 ± 0.082.47 ± 0.151.35 ± 0.071.15 ± 0.08d
Serotonin65.30 ± 0.293.64 ± 0.131.97 ± 0.081.67 ± 0.06d
IBMX63.98 ± 0.243.22 ± 0.091.75 ± 0.071.47 ± 0.06d
SDR68.50 ± 0.453.71 ± 0.352.02 ± 0.151.68 ± 0.12b
SDR + Ami60.33 ± 0.052.88 ± 0.121.53 ± 0.071.35 ± 0.08d
Table 2 Relationship between short-circuit current and epithelial oxygen consumption of the isolated mucosa of rat sigmoid colon
ConditionComparisonR2
BaselineIscvs total QO20.586b
Iscvs serosal QO20.620c
Iscvs mucosal QO20.299
Mucosal hypoxiaIscvs total QO20.633d
Iscvs serosal QO20.569g
Iscvs mucosal QO20.388
Serosal hypoxiaIscvs total QO20.164
Iscvs serosal QO20.315
Iscvs mucosal QO20.361