Embrionary way to create a fatty liver in portal hypertension

Table 1 Similarities between the inflammatory changes developed after triple partial portal vein ligation in the rat and the extra-embryonic functions in mammals

Inflammatory phenotype		Extra-embryonic and embryonic functions
Neurogenic	Portal ischemia Hepatic arterial reperfusion Neuroendocrine response Hyperdynamic circulation Mild edema of space of Disse	Coelomic-amniotic functions Neurogenic potential Interstitial edema Bacteriostasis Anti-inflammation
Immune	Kupffer cell and hepatic stellate cell activation Leukocyte infiltration Acute phase response Angiogenesis Hepatic steatosis	Trophoblastic-yolk sac functions Digestive (phagocytic) functions Acute phase proteins Angiogenic switch Lipid and protein nutrients (vitellum)
Endocrine	Sinusoidal remodeling Capillarization of hepatic sinusoids Perisinusoidal fibrosis Steatohepatitis	Gastrulation-like functions Epithelial-mesenchymal transition Intra-embryonic mesenchyma