Clinical impacts of mesothelin expression in gastrointestinal carcinomas

Table 1 Mesothelin expression in human cancer detected by immunohistochemistry

Tumour	Mesothelin expressions (%)	Comments	Ref.
Pancreatic cancer	86-100	Co-expression of mesothelin and CA125 group associated with a poorer patient prognosis	[6,16,17]
Gastric cancer	29-59	Luminal membrane expression is one of the poor prognostic factors	[6,18,27,35]
Extrahepatic bile duct cancer	72-100	Luminal membrane expression or cytoplasmic expression of mesothelin could be a reliable prognostic factor	[6,21]
Colorectal cancer	28-58	Luminal membrane expression was associated with lymphatic invasion	[6,20]
Intraductal papillary mucinous neoplasm	57	Luminal membrane expression was correlated with the histological classification of the tumor and the recurrence rate	[19]