Copyright ©The Author(s) 2016.
World J Gastrointest Pathophysiol. Feb 15, 2016; 7(1): 48-58
Published online Feb 15, 2016. doi: 10.4291/wjgp.v7.i1.48
Figure 2
Figure 2 Consequences of sustained increased intracellular calcium in pancreatic acinar cells. Ethanol and its metabolic by-products can cause sustained increases in the level of intracellular calcium. Sustained increases in intracellular calcium results in cellular changes that can damage pancreatic acinar cells. Many of these changes can predispose individuals to the development of alcoholic acute pancreatitis. MPTP: Mitochondrial permeability transition pore; ER: Endoplasmic reticulum.