|
1
|
Dimanov SN, Stoev AL, Yotsova RV, Stoev LL, Yankov YG, Ruseva YR. A Rare Case of Cementoblastoma of the Second Right Maxillary Premolar in a 30-Year-Old Man. Cureus 2024; 16:e73737. [PMID: 39677262 PMCID: PMC11646362 DOI: 10.7759/cureus.73737] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 11/15/2024] [Indexed: 12/17/2024] Open
Abstract
Cementoblastoma is a benign odontogenic mesenchymal tumor characterized by cementum production. Cementoblastoma is considered a relatively rare neoplasm with a predilection to the posterior region of the mandible. The main clinical differential diagnoses include hypercementosis, cemento-osseous dysplasia, condensing osteitis, idiopathic osteosclerosis, osteoblastoma, odontoma, and osteosarcoma. Imaging findings may be pathognomonic when demonstrative. Although rather identical histologically, cementoblastoma exhibits unequivocal fusion to the root of the tooth, which distinguishes it from osteoblastoma. We present a case of a 30-year-old man with cementoblastoma arising in an unusual location: the root of the second right premolar of the maxilla.
Collapse
Affiliation(s)
- Simeon N Dimanov
- Department of Oral Surgery, Medical University "Prof. Dr. Paraskev Stoyanov", Varna, BGR
| | - Alexandar L Stoev
- Faculty of Dentistry, Medical University "Prof. Dr. Paraskev Stoyanov", Varna, BGR
| | - Ralitsa V Yotsova
- Department of Oral Surgery, Medical University "Prof. Dr. Paraskev Stoyanov", Varna, BGR
| | - Lyuben L Stoev
- Department of General and Clinical Pathology, Forensic Medicine and Deontology, Medical University "Prof. Dr. Paraskev Stoyanov", Varna, BGR
| | - Yanko G Yankov
- Clinic of Maxillofacial Surgery, University Hospital "St. Marina", Varna, BGR
- Department of General and Operative Surgery, Medical University "Prof. Dr. Paraskev Stoyanov", Varna, BGR
| | - Yoana R Ruseva
- Department of Pediatric Dentistry, Medical University "Prof. Dr. Paraskev Stoyanov", Varna, BGR
| |
Collapse
|
|
2
|
Choi WJ, Lee P, Thomas PC, Rath TJ, Mogensen MA, Dalley RW, Wangaryattawanich P. Imaging approach for jaw and maxillofacial bone tumors with updates from the 2022 World Health Organization classification. World J Radiol 2024; 16:294-316. [PMID: 39239241 PMCID: PMC11372550 DOI: 10.4329/wjr.v16.i8.294] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 08/05/2024] [Revised: 08/22/2024] [Accepted: 08/27/2024] [Indexed: 08/28/2024] Open
Abstract
Jaw and maxillofacial bone lesions encompass a wide variety of both neoplastic and non-neoplastic pathologies. These lesions can arise from various tissues, including bone, cartilage, and soft tissue, each presenting distinct challenges in diagnosis and treatment. While some pathologies exhibit characteristic imaging features that aid in diagnosis, many others are nonspecific. This overlap often necessitates a multimodal imaging approach, combining techniques such as radiographs, computed tomography, and magnetic resonance imaging to achieve a diagnosis or narrow the diagnostic considerations. This article provides a comprehensive review of the imaging approach to jaw and maxillofacial bone tumors, including updates on the 2022 World Health Organization classification of these tumors. The relevant anatomy of the jaw and dental structures that is important for accurate imaging interpretation is discussed.
Collapse
Affiliation(s)
- Woongsoon John Choi
- Division of Neuroradiology, Department of Radiology, University of Washington School of Medicine, Seattle, WA 98195, United States
- Department of Radiology, M&S Radiology Associates, San Antonio, TX 78217, United States
| | - Peggy Lee
- Division of Oral Radiology, University of Washington School of Dentistry, Seattle, WA 98195, United States
| | - Penelope C Thomas
- Division of Neuroradiology, Department of Radiology, University of Washington School of Medicine, Seattle, WA 98195, United States
| | - Tanya J Rath
- Division of Neuroradiology, Department of Radiology, Mayo Clinic, Phoenix, AZ 85054, United States
| | - Monique A Mogensen
- Division of Neuroradiology, Department of Radiology, University of Washington School of Medicine, Seattle, WA 98195, United States
| | - Roberta W Dalley
- Division of Neuroradiology, Department of Radiology, University of Washington School of Medicine, Seattle, WA 98195, United States
| | - Pattana Wangaryattawanich
- Division of Neuroradiology, Department of Radiology, University of Washington School of Medicine, Seattle, WA 98195, United States
| |
Collapse
|
|
3
|
Jeyaraj P. The Curious Case of a 'Maverick' Cementoblastoma! J Maxillofac Oral Surg 2024; 23:692-705. [PMID: 38911399 PMCID: PMC11189863 DOI: 10.1007/s12663-024-02181-w] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/23/2023] [Accepted: 04/01/2024] [Indexed: 06/25/2024] Open
Abstract
Introduction The Cementoblastoma is a benign ectomesenchymal odontogenic neoplasm of the jaw, arising from an exuberant production of cemental tissue continuous with the roots of teeth (usually mandibular posteriors), resulting in a calcified mass adherent with the root apices. Case Presentation A curious case of a large Cementoblastoma, the size and shape of a ping pong ball, is presented, the first of its kind ever reported to involve the internal / medial / lingual aspect of the mandible, and presenting with unusual and deviant features. Discussion & Conclusion The Cementoblastoma is usually associated with certain inherent and pathognomonic features, making it rather straightforward to identify and diagnose. Strikingly uncharacteristic clinical, radiographic and histologic attributes presented in this case, made this 'out of the ordinary' and 'Maverick'-like Cementoblastoma, arduous to diagnose, nevertheless, making it an interesting, informative and curious Case Study. This report has brought to light for the first time, several new facets of the Cementoblastoma.
Collapse
Affiliation(s)
- Priya Jeyaraj
- Commandant Armed Forces Dental Clinic, New Delhi, 110001 India
| |
Collapse
|
|
4
|
Noviyanti D, Kuntara A, Oli'i EM, Agustina H. Giant cementoblastoma involving multiple teeth: A rare case report and review of differential diagnoses. Radiol Case Rep 2024; 19:2085-2092. [PMID: 38523691 PMCID: PMC10958121 DOI: 10.1016/j.radcr.2024.02.026] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/31/2023] [Revised: 01/26/2024] [Accepted: 02/06/2024] [Indexed: 03/26/2024] Open
Abstract
Cementoblastoma, a rare odontogenic benign tumor characterized by calcified cementum-like deposits produced by cementoblasts fused with the tooth root, represents a minute proportion of all odontogenic tumors, with a prevalence ranging from less than 1% to 6.2%. We present a case of a 19-year-old female experiencing pain, progressive swelling, and facial asymmetry in the left lower region over the 1 year ago. Physical examination revealed diffuse swelling in the left mandibular area, demonstrating tenderness and bony hardness on palpation. Radiographic findings displayed a giant, well-defined, relatively round, radiopaque mass, partially delineated by a thin radiolucent halo, and adhered to the roots of the teeth. Computed Tomography imaging revealed an osteoblastic hyperdense mass with extensive buccal and lingual extension. Sagittal images illustrated the mass's continuity with the root apex of the first molar, accompanied by a well-defined hypodense border. A biopsy confirmed the diagnosis of cementoblastoma, leading to the patient undergoing a left hemimandibulectomy. Given the various periapical radiopaque lesions that serve as potential differential diagnoses for cementoblastoma, the ability of the radiologist to distinguish their imaging characteristics plays a crucial role in determining an accurate diagnosis.
Collapse
Affiliation(s)
- Dwi Noviyanti
- Department of Radiology, Faculty of Medicine, University of Padjadjaran, Bandung City, West Java 40161, Indonesia
| | - Atta Kuntara
- Department of Radiology, Faculty of Medicine, University of Padjadjaran, Bandung City, West Java 40161, Indonesia
| | - Eka Marwansyah Oli'i
- Department Oral and Maxillofacial Surgery, Faculty of Medicine, University of Padjadjaran, Bandung City, West Java 40161, Indonesia
| | - Hasrayati Agustina
- Department of Pathological Anatomy, Faculty of Medicine, University of Padjadjaran, Dr. Hasan Sadikin General Hospital, Bandung City, West Java 40161, Indonesia
| |
Collapse
|
|
5
|
Oya K, Takeshita A, Wakamori K, Song M, Kimura H, Hirose K, Shimamoto H, Sato S, Matsunaga K, Uzawa N, Toyosawa S. Recurrent cementoblastoma with multifocal growth and cellular atypia: a case report. Diagn Pathol 2024; 19:57. [PMID: 38589906 PMCID: PMC11000364 DOI: 10.1186/s13000-024-01479-0] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/09/2024] [Accepted: 03/18/2024] [Indexed: 04/10/2024] Open
Abstract
BACKGROUND Cementoblastoma is a rare odontogenic tumor characterized by the formation of osteocementum-like tissue on a tooth root directly by neoplastic cementoblasts. Although it is categorized as benign, it has a high potential for growth with a certain degree of recurrence risk. However, there are only a few studies describing the features of recurrent cementoblastoma. The diagnosis of recurrent cementoblastoma is challenging not only due to its cytological atypia but also because of its large size and multicentric growth pattern. These characteristics suggest a potential for malignancy. CASE PRESENTATION A 29-year-old woman was transferred to our university dental hospital complaining of swelling of the right mandible. She had a history of enucleation of cementoblastoma associated with the third molar of the right mandible. Five years after the initial treatment, imaging demonstrated well-circumscribed multicentric radiopaque lesions in the same area. Histologically, the lesion consisted of osteocementum-like tissue rimmed with polygonal or plump tumor cells. Several cells were large epithelioid cells with bizarre nucleoli, which may be reminiscent of malignant tumors. Otherwise, there were no apparent malignant findings, including proliferative activity or atypical mitotic figure. Besides, tumor cells were positive for c-FOS, a marker of osteoblastoma and cementoblastoma. Eventually, the patient was diagnosed with recurrent cementoblastoma. CONCLUSIONS Pathological analyses of this case suggested that the recurrent event in the cementoblastoma altered its growth pattern and tumor cell shape. Moreover, in the case of enucleation surgery, long-term follow-up is important because there is some recurrent risk of cementoblastoma, although it is not high.
Collapse
Affiliation(s)
- Kaori Oya
- Division of Clinical Laboratory, Osaka University Dental Hospital, Suita, Osaka, Japan
| | - Akinori Takeshita
- Department of Oral and Maxillofacial Oncology and Surgery, Osaka University Graduate School of Dentistry, Suita, Osaka, Japan
| | - Kanta Wakamori
- Department of Oral and Maxillofacial Oncology and Surgery, Osaka University Graduate School of Dentistry, Suita, Osaka, Japan
| | - Misa Song
- Department of Diagnostic Pathology, Itami City Hospital, Itami, Hyogo, Japan
| | - Hayato Kimura
- Department of Diagnostic Pathology, Itami City Hospital, Itami, Hyogo, Japan
| | - Katsutoshi Hirose
- Department of Oral and Maxillofacial Pathology, Osaka University Graduate School of Dentistry, Suita, Osaka, Japan
| | - Hiroaki Shimamoto
- Department of Oral and Maxillofacial Radiology, Osaka University Graduate School of Dentistry, Suita, Osaka, Japan
| | - Sunao Sato
- Department of Oral and Maxillofacial Pathology, Osaka University Graduate School of Dentistry, Suita, Osaka, Japan
| | - Kazuhide Matsunaga
- Department of Oral and Maxillofacial Oncology and Surgery, Osaka University Graduate School of Dentistry, Suita, Osaka, Japan
| | - Narikazu Uzawa
- Department of Oral and Maxillofacial Oncology and Surgery, Osaka University Graduate School of Dentistry, Suita, Osaka, Japan
| | - Satoru Toyosawa
- Division of Clinical Laboratory, Osaka University Dental Hospital, Suita, Osaka, Japan.
- Department of Oral and Maxillofacial Pathology, Osaka University Graduate School of Dentistry, Suita, Osaka, Japan.
| |
Collapse
|
|
6
|
Taghsimi K, Vasilyev AV, Kuznetsova VS, Galtsova AV, Badalyan VA, Babichenko II. Efficiency and Safety of Dental Implantation in the Area of Hyperdense Jaw Lesions: A Narrative Review. Dent J (Basel) 2022; 10:dj10060107. [PMID: 35735649 PMCID: PMC9222039 DOI: 10.3390/dj10060107] [Citation(s) in RCA: 6] [Impact Index Per Article: 2.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/15/2022] [Revised: 05/30/2022] [Accepted: 06/06/2022] [Indexed: 02/04/2023] Open
Abstract
Background. Mineralized lesions of the jaws are often found incidentally on radiographs and computed tomography. Most of them are benign, and only a few rare cases are associated with malignant transformation. However, there is little clinical data on successful rehabilitation with implants in patients with mineralized lesions. This narrative review aimed to study the efficiency and safety of dental implantation in the area of hyperdense lesions. Materials and Methods. A PubMed, Google Scholar, and Science Direct database search was carried out with keywords and manually. Results. The literature exploration identified 323 articles; only 19 of them matched the search criteria and reported cases about dental implantation in the lesion area. It has been shown that in 84.2% of described cases, dental implantation was successful: in the osteoid osteoma, odontoma, cementoblastoma, idiopathic osteosclerosis, and condensing osteitis areas dental implantation was performed without any complications. The possibility of lesion recurrence and implant failure limited the use of dental implants in the area of osteoblastoma and cemento-osseous dysplasia. Although most cases of dental implantation in hyperdense jaw lesions were successful and were not accompanied by complications, further research is needed.
Collapse
Affiliation(s)
- Kimya Taghsimi
- Department of Pathological Anatomy, Peoples’ Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St., 117198 Moscow, Russia; (A.V.V.); (A.V.G.); (I.I.B.)
- Correspondence:
| | - Andrey Vyacheslavovich Vasilyev
- Department of Pathological Anatomy, Peoples’ Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St., 117198 Moscow, Russia; (A.V.V.); (A.V.G.); (I.I.B.)
- Central Research Institute of Dental and Maxillofacial Surgery, Timur Frunze St., 16, 119021 Moscow, Russia; (V.S.K.); (V.A.B.)
- Research Centre for Medical Genetics, Moskvorechye St., 1, 115478 Moscow, Russia
- Department of Dentistry of the Institute of Dentistry E.V. Borovsky, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 119991 Moscow, Russia
| | - Valeriya Sergeevna Kuznetsova
- Central Research Institute of Dental and Maxillofacial Surgery, Timur Frunze St., 16, 119021 Moscow, Russia; (V.S.K.); (V.A.B.)
- Research Centre for Medical Genetics, Moskvorechye St., 1, 115478 Moscow, Russia
| | - Angelina Vladimirovna Galtsova
- Department of Pathological Anatomy, Peoples’ Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St., 117198 Moscow, Russia; (A.V.V.); (A.V.G.); (I.I.B.)
| | - Varditer Agabekovna Badalyan
- Central Research Institute of Dental and Maxillofacial Surgery, Timur Frunze St., 16, 119021 Moscow, Russia; (V.S.K.); (V.A.B.)
- Department of Dentistry of the Institute of Dentistry E.V. Borovsky, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 119991 Moscow, Russia
| | - Igor Ivanovich Babichenko
- Department of Pathological Anatomy, Peoples’ Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St., 117198 Moscow, Russia; (A.V.V.); (A.V.G.); (I.I.B.)
- Central Research Institute of Dental and Maxillofacial Surgery, Timur Frunze St., 16, 119021 Moscow, Russia; (V.S.K.); (V.A.B.)
| |
Collapse
|
|
7
|
Qureshi MB, Tariq MU, Abdul-Ghafar J, Raza M, Din NU. Concomitant bilateral mandibular cemento-ossifying fibroma and cementoblastoma: case report of an extremely rare occurrence. BMC Oral Health 2021; 21:437. [PMID: 34493273 PMCID: PMC8425131 DOI: 10.1186/s12903-021-01794-8] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/22/2021] [Accepted: 07/21/2021] [Indexed: 11/16/2022] Open
Abstract
BACKGROUND Cemento-ossifying fibroma (COF) and cementoblastoma (CB) are rare benign odontogenic tumors with a predilection for the mandible. Cemento-ossifying fibroma is a fibro-osseous lesion that originates in the tooth bearing areas of jaw and shows cementum-like tissue in a fibrotic stroma. Cementoblastoma is classically related to roots of teeth with the presence of calcified cementum-like material. To date, only a single case of concomitant unilateral COF and CB has been reported in the literature. CASE PRESENTATION We present an unusual case of a 37-year-old female who presented with two discrete bilateral swellings in the right and left mandible for 10 years. The larger tumor involved the left posterior mandible with extension anteriorly to the left and right anterior mandibles, and the smaller tumor was present in right posterior mandible. Radiology revealed two distinct lesions involving both sides of mandible. Histopathological examination showed characteristic features of cemento-ossifying fibroma in sections of the larger tumor and cementoblastoma in sections of smaller tumor. CONCLUSION This case shows the very unique bilateral co-existence of COF and CB, the second case reported in literature to date.
Collapse
Affiliation(s)
- Madiha Bilal Qureshi
- Department of Pathology and Laboratory Medicine, Aga Khan University, Karachi, Pakistan
| | - Muhammad Usman Tariq
- Department of Pathology and Laboratory Medicine, Aga Khan University, Karachi, Pakistan
| | - Jamshid Abdul-Ghafar
- Department of Pathology and Clinical Laboratory, French Medical Institute for Mothers and Children (FMIC), Kabul, Afghanistan
| | - Muhammad Raza
- Department of Pathology and Laboratory Medicine, Aga Khan University, Karachi, Pakistan
| | - Nasir Ud Din
- Department of Pathology and Laboratory Medicine, Aga Khan University, Karachi, Pakistan
| |
Collapse
|
|
8
|
Holmes KR, Holmes RD, Martin M, Murray N. Practical Approach to Radiopaque Jaw Lesions. Radiographics 2021; 41:1164-1185. [PMID: 34086497 DOI: 10.1148/rg.2021200187] [Citation(s) in RCA: 7] [Impact Index Per Article: 1.8] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/11/2022]
Abstract
Radiopaque lesions of the jaw are myriad in type and occasionally protean in appearance. In turn, the radiologic analysis of these lesions requires a systematic approach and a broad consideration of clinical and imaging characteristics to enable reliable radiologic diagnosis. Initially categorizing lesions by attenuation pattern provides a practical framework for organizing radiopaque jaw lesions that also reflects important tissue characteristics. Specifically, the appearance of radiopaque lesions can be described as (a) densely sclerotic, (b) ground glass, or (c) mixed lytic-sclerotic, with each category representing a distinct although occasionally overlapping differential diagnosis. After characterizing attenuation pattern, the appreciation of other radiologic features, such as margin characteristics or relationship to teeth, as well as clinical features including demographics and symptoms, can aid in further narrowing the differential diagnosis and lend confidence to clinical decision making. The authors review the potential causes of a radiopaque jaw lesion, including pertinent clinical and radiologic features, and outline a simplified approach to its radiologic diagnosis, with a focus on cross-sectional CT. An invited commentary by Buch is available online. ©RSNA, 2021.
Collapse
Affiliation(s)
- Kenneth R Holmes
- From the Departments of Medicine (K.R.H.) and Radiology (R.D.H.), University of British Columbia, 2775 Laurel St, 11th Floor, Vancouver, BC, Canada V5Z 1M9; BC Cancer Agency, Vancouver, British Columbia, Canada (M.M.); and Vancouver General Hospital, Vancouver, British Columbia, Canada (N.M.)
| | - R Davis Holmes
- From the Departments of Medicine (K.R.H.) and Radiology (R.D.H.), University of British Columbia, 2775 Laurel St, 11th Floor, Vancouver, BC, Canada V5Z 1M9; BC Cancer Agency, Vancouver, British Columbia, Canada (M.M.); and Vancouver General Hospital, Vancouver, British Columbia, Canada (N.M.)
| | - Montgomery Martin
- From the Departments of Medicine (K.R.H.) and Radiology (R.D.H.), University of British Columbia, 2775 Laurel St, 11th Floor, Vancouver, BC, Canada V5Z 1M9; BC Cancer Agency, Vancouver, British Columbia, Canada (M.M.); and Vancouver General Hospital, Vancouver, British Columbia, Canada (N.M.)
| | - Nicolas Murray
- From the Departments of Medicine (K.R.H.) and Radiology (R.D.H.), University of British Columbia, 2775 Laurel St, 11th Floor, Vancouver, BC, Canada V5Z 1M9; BC Cancer Agency, Vancouver, British Columbia, Canada (M.M.); and Vancouver General Hospital, Vancouver, British Columbia, Canada (N.M.)
| |
Collapse
|
|
9
|
Abstract
Sclerotic lesions of the jaw are uncommon but may be clinically relevant. In this pictorial review, the most common sclerotic lesions are discussed. Three categories of lesions are distinguished; odontogenic sclerotic lesions, non-odontogenic sclerotic lesions, and mixed lytic-sclerotic lesions. In each group, non-neoplastic conditions are discussed first, followed by benign and malignant neoplasms. For each disease a brief overview is given, including histological features, epidemiology, symptoms, typical location, imaging features, and treatment. This review emphasizes which basic observations are essential to the evaluation of sclerotic jaw lesions and what elements have to be taken into account to create a proper differential diagnosis.
Collapse
|
|
10
|
Van Hoe S, Shaheen E, de Faria Vasconcelos K, Schoenaers J, Politis C, Jacobs R. Contribution of three-dimensional images in the planning of cementoblastoma resection. BJR Case Rep 2021; 7:20200156. [PMID: 34131494 PMCID: PMC8171136 DOI: 10.1259/bjrcr.20200156] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/14/2020] [Revised: 12/17/2020] [Accepted: 12/20/2020] [Indexed: 12/02/2022] Open
Abstract
Cementoblastomas are rare benign tumours that represent less than 1% of all odontogenic tumours. Complete resection is mandatory to avoid recurrence. This case report describes the contribution of three-dimensional imaging and three-dimensional printing in the pre-operative surgical planning of a large cementoblastoma that not only caused substantial compression on the inferior alveolar and mental nerves, but also caused thinning and partial erosion of the lingual and vestibular cortical bone, thus increasing the risk of pre-operative mandibular fracture.
Collapse
Affiliation(s)
| | - Eman Shaheen
- OMFS-IMPATH Research Group, Department of Imaging & Pathology, Faculty of Medicine, KU Leuven. Department of Oral and Maxillofacial Surgery, University Hospitals Leuven, Leuven, Belgium
| | - Karla de Faria Vasconcelos
- OMFS-IMPATH Research Group, Department of Imaging & Pathology, Faculty of Medicine, KU Leuven. Department of Oral and Maxillofacial Surgery, University Hospitals Leuven, Leuven, Belgium
| | - Joseph Schoenaers
- OMFS-IMPATH Research Group, Department of Imaging & Pathology, Faculty of Medicine, KU Leuven. Department of Oral and Maxillofacial Surgery, University Hospitals Leuven, Leuven, Belgium
| | - Constantinus Politis
- OMFS-IMPATH Research Group, Department of Imaging & Pathology, Faculty of Medicine, KU Leuven. Department of Oral and Maxillofacial Surgery, University Hospitals Leuven, Leuven, Belgium
| | | |
Collapse
|
|
11
|
Mupparapu M, Shi KJ, Ko E. Differential Diagnosis of Periapical Radiopacities and Radiolucencies. Dent Clin North Am 2020; 64:163-189. [PMID: 31735225 DOI: 10.1016/j.cden.2019.08.010] [Citation(s) in RCA: 5] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 06/10/2023]
Abstract
Periapical pathoses represent changes noted at the apices of teeth within the alveolar process that are suspected on examination, visualized via imaging, and confirmed via histopathology. They can be bone forming or destructive. There are pathologic entities that show both types of changes at the apical regions. These lesions must be identified if they are odontogenic in origin because treatment modalities differ. This article discusses identification of radiopaque and radiolucent lesions noted on radiographs. The common opacities and lucencies are described. When required, advanced imaging is used to depict changes within the bone near the periapical regions of mandibular and maxillary teeth.
Collapse
Affiliation(s)
- Mel Mupparapu
- Department of Oral Medicine, Robert Schattner Center, University of Pennsylvania School of Dental Medicine, 240 South 40th Street, Philadelphia, PA 19104, USA.
| | - Katherine Jie Shi
- Department of Endodontics, Tufts University School of Dental Medicine, 1 Kneeland Street, Boston, MA 02111, USA
| | - Eugene Ko
- Department of Oral Medicine, Robert Schattner Center, University of Pennsylvania School of Dental Medicine, 240 South 40th Street, Philadelphia, PA 19104, USA
| |
Collapse
|
|
12
|
|
|
13
|
da Silva HF, Sigua-Rodriguez EA, de Moraes M. Surgical treatment of cementoblastoma in maxillary associated on dentofacial deformity. ORAL AND MAXILLOFACIAL SURGERY CASES 2019. [DOI: 10.1016/j.omsc.2018.10.003] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 12/01/2022] Open
|
|
14
|
Borges DC, Rogério de Faria P, Júnior HM, Pereira LB. Conservative Treatment of a Periapical Cementoblastoma: A Case Report. J Oral Maxillofac Surg 2019; 77:272.e1-272.e7. [DOI: 10.1016/j.joms.2018.10.003] [Citation(s) in RCA: 5] [Impact Index Per Article: 0.8] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/17/2018] [Revised: 10/04/2018] [Accepted: 10/04/2018] [Indexed: 10/28/2022]
|
|
15
|
Nagvekar S, Syed S, Spadigam A, Dhupar A. Rare presentation of cementoblastoma associated with the deciduous maxillary second molar. BMJ Case Rep 2017; 2017:bcr-2017-221977. [PMID: 29170176 DOI: 10.1136/bcr-2017-221977] [Citation(s) in RCA: 5] [Impact Index Per Article: 0.6] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/03/2022] Open
Abstract
Cementoblastoma is a benign odontogenic neoplasm accounting for less than 0.69%-8% of all odontogenic tumours and is characterised by the presence of sheets of cementum-like tissue demonstrating large number of reversal lines. It shows an unlimited growth potential and a recurrence rate as high as 37.1%. It most commonly affects the permanent mandibular molars. This paper presents the third reported case of cementoblastoma affecting the deciduous maxillary posterior dentition. A 12-year-old male patient reported to the Department of Oral and Maxillofacial Pathology with a chief complaint of pain and swelling in relation to the deciduous maxillary left second molar.
Collapse
Affiliation(s)
- Shruti Nagvekar
- Department of Oral and Maxillofacial Pathology, Goa Dental College and Hospital, Bambolim, Goa, India
| | - Shaheen Syed
- Department of Oral and Maxillofacial Pathology, Goa Dental College and Hospital, Bambolim, Goa, India
| | - Anita Spadigam
- Department of Oral and Maxillofacial Pathology, Goa Dental College and Hospital, Bambolim, Goa, India
| | - Anita Dhupar
- Department of Oral and Maxillofacial Pathology, Goa Dental College and Hospital, Bambolim, Goa, India
| |
Collapse
|
|
16
|
Chrcanovic BR, Gomez RS. Cementoblastoma: An updated analysis of 258 cases reported in the literature. J Craniomaxillofac Surg 2017; 45:1759-1766. [PMID: 28869132 DOI: 10.1016/j.jcms.2017.08.002] [Citation(s) in RCA: 19] [Impact Index Per Article: 2.4] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/29/2016] [Revised: 06/07/2017] [Accepted: 08/01/2017] [Indexed: 10/19/2022] Open
Abstract
PURPOSE To investigate the recurrence rate of cementoblastomas for different variables aside from the clinical/radiologic features. METHODS An electronic search was undertaken in November/2016. Eligibility criteria included publications having enough clinical/radiological/histological information to confirm the diagnosis. RESULTS 141 publications (258 cementoblastomas) were included. There was an equal sex distribution. There was a high prevalence in the second/third decades of life, in the posterior regions, and in mandibular first molars. Lesions were commonly associated with bone expansion (74.9%), presence of clinical symptoms (70.2%), vital teeth (78%), root resorption (59.8%). Observations not as frequent: cortical bone perforation (16.3%), inferior displacement of the mandibular canal (23.6%). Treatment was reported for 229 cases. Twenty (11.8%) out of 170 recurred. Preservation of the involved teeth and location seem to not influence the recurrence rate, but there was a 687% higher probability (odds ratio 7.875; p = 0.048) of recurrence for lesions associated with bone expansion, and a 217% higher probability (odds ratio 3.173; p = 0.023) of recurrence for lesions presenting cortical bone perforation. CONCLUSIONS Although the recurrence rate of cementoblastomas is not as high as previously believed, it is a relevant phenomenon (11.8%). The presence of bone expansion and cortical bone perforation seem to influence the recurrence rate.
Collapse
Affiliation(s)
- Bruno Ramos Chrcanovic
- Department of Prosthodontics (Head: Dr. Ann Wennerberg, DDS, PhD), Faculty of Odontology, Malmö University, Malmö, Sweden.
| | - Ricardo Santiago Gomez
- Department of Oral Surgery and Pathology (Head: Dr. Henrique Pretti), School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
| |
Collapse
|
|
17
|
Silva BSF, Bueno MR, Yamamoto-Silva FP, Gomez RS, Peters OA, Estrela C. Differential diagnosis and clinical management of periapical radiopaque/hyperdense jaw lesions. Braz Oral Res 2017; 31:e52. [PMID: 28678971 DOI: 10.1590/1807-3107bor-2017.vol31.0052] [Citation(s) in RCA: 10] [Impact Index Per Article: 1.3] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/03/2017] [Accepted: 05/21/2017] [Indexed: 11/22/2022] Open
Abstract
Great attention has been given to the study of radiolucent periapical lesions to avert possible misdiagnosis of apical periodontitis associated with certain radiolucent non-endodontic lesions. However, there are a significant number of radiopaque lesions found in the periapical region, which could be equally relevant to endodontic practice. The diagnosis and management of these radiopaque/hyperdense lesions could be challenging to the endodontist. These bone alterations could be neoplastic, dysplastic or of metabolic origin. In the context of the more widespread use of cone-beam CT, a detailed review of radiopaque inflammatory and non-inflammatory lesions is timely and may aid clinicians perform a differential diagnosis of these lesions. Distinguishing between inflammatory and non-inflammatory lesions simplifies diagnosis and consequently aids in choosing the correct therapeutic regimen. This review discusses the literature regarding the clinical, radiographic, histological and management aspects of radiopaque/hyperdense lesions, and illustrates the differential diagnoses of these lesions.
Collapse
Affiliation(s)
| | - Mike Reis Bueno
- Universidade de Cuiabá - UNIC, School of Dentistry, Department of Stomatology, University of Cuiabá, Cuibá, MT, Brazil
| | - Fernanda P Yamamoto-Silva
- Universidade Federal de Goiás - UFG, School of Dentistry, Department of Stomatologic Sciences, Goiânia, GO, Brazil
| | - Ricardo Santiago Gomez
- Universidade Federal de Minas Gerias - UFMG, School of Dentistry, Department of Oral Surgery and Pathology, Belo Horizonte, MG, Brazil
| | - Ove Andreas Peters
- University of the Pacific, Arthur A. Dugoni School of Dentistry, Department of Endodontics, San Francisco, CA, United States of America
| | - Carlos Estrela
- Universidade Federal de Goiás - UFG, School of Dentistry, Department of Stomatologic Sciences, Goiânia, GO, Brazil
| |
Collapse
|
|
18
|
Mortazavi H, Baharvand M, Rahmani S, Jafari S, Parvaei P. Radiolucent rim as a possible diagnostic aid for differentiating jaw lesions. Imaging Sci Dent 2015; 45:253-61. [PMID: 26730374 PMCID: PMC4697011 DOI: 10.5624/isd.2015.45.4.253] [Citation(s) in RCA: 15] [Impact Index Per Article: 1.5] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/22/2015] [Revised: 09/01/2015] [Accepted: 09/05/2015] [Indexed: 01/30/2023] Open
Abstract
In this study, we formulate a new proposal that complements previous classifications in order to assist dental practitioners in performing a differential diagnosis based on patients' radiographs. We used general search engines and specialized databases such as Google Scholar, PubMed, PubMed Central, MedLine Plus, Science Direct, Scopus, and well-recognized textbooks to find relevant studies by using keywords such as "jaw disease," "jaw lesions," "radiolucent rim," "radiolucent border," and "radiolucent halo." More than 200 articles were found, of which 70 were broadly relevant to the topic. We ultimately included 50 articles that were closely related to the topic of interest. When the relevant data were compiled, the following eight lesions were identified as having a radiolucent rim: periapical cemento-osseous dysplasia, focal cemento-osseous dysplasia, florid cemento-osseous dysplasia, cemento-ossifying fibroma, osteoid osteoma, osteoblastoma, odontoma, and cementoblastoma. We propose a novel subcategory, jaw lesions with a radiolucent rim, which includes eight entities. The implementation of this new category can help improve the diagnoses that dental practitioners make based on patients' radiographs.
Collapse
Affiliation(s)
- Hamed Mortazavi
- Department of Oral Medicine, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
| | - Maryam Baharvand
- Department of Oral Medicine, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
| | - Somayeh Rahmani
- Department of Oral Medicine, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
| | - Soudeh Jafari
- Department of Oral Medicine, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
| | - Parvin Parvaei
- Department of Oral Medicine, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
| |
Collapse
|
|
19
|
Abstract
We present a rare case of radiopaque lesion with radiolucent rim in the right body of mandible, with history of extraction of involved tooth, which made diagnosis confusing unless pre-extraction intraoral periapical radiography radiograph was recovered, finally diagnosed as benign cementoblastoma. It was surgically managed, with no recurrence of the lesion more than 2 years of follow-up. Benign cementoblastoma is a rare, benign tumor of odontogenic ectomesenchymal origin, usually associated with roots of first mandibular molar.
Collapse
Affiliation(s)
- Neeta Sharma
- Department of Oral Medicine and Radiology, Himachal Pradesh Government Dental College, Shimla, Himachal Pradesh, India
| |
Collapse
|
|
20
|
Multiple cementoblastoma: a rare case report. Case Rep Dent 2013; 2013:828373. [PMID: 24027644 PMCID: PMC3763579 DOI: 10.1155/2013/828373] [Citation(s) in RCA: 4] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/28/2013] [Accepted: 07/24/2013] [Indexed: 11/18/2022] Open
Abstract
Benign cementoblastoma is a rare ectomesenchymal odontogenic tumor that originates from the root of the tooth and that is characterized by the formation of cementum-like tissue. A 60-year old man was referred to us complaining of pain in his right jaw. The patient underwent TC dental scan of the mandible, which highlighted the presence of three well-circumscribed, round, unilocular neoformations of radiopaque appearance with a radiotransparent edge, one of which was in close contact with the roots of the lower right second molar. Microscopic examination of the greater sample consisted, in its central portion, of dense mineralized acellular trabeculae of basophilic tissue cement-like, devoid of vessels, adhering to the root of the tooth, while peripherally was observed a zone of vascularized osteoid surrounded, occasionally, by a thin rim of cementoblasts mixed with fibrous tissue and inflammatory elements. This lesion was diagnosed as cementoblastoma. The second lesion appeared radiologically and histologically entirely identical to cementoblastoma, but it did not show the intimate association with the root of involved tooth. After a careful review of the literature, the diagnosis of residual cementoblastoma was made. The clinicopathologic features, treatment, and prognosis of this rare tumor are here discussed for the young dental practitioner.
Collapse
|
|
21
|
Abstract
Benign cementoblastoma is a rare odontogenic tumor characterized by the formation of a mass of cementum or cementum-like tissue attached to the roots of a tooth. Cementoblastoma are distinctive but relatively uncommon tumors. The clinical, radiographic, and histopathologic features of a case of benign cementoblastoma are presented in this paper along with a brief review of the literature.
Collapse
Affiliation(s)
- Leena S Sankari
- Department of Oral Pathology, Adhiparasakthi Dental College and Hospital, Melmaruvathur, Kanchipuram, India
| | | |
Collapse
|
|
22
|
Cementoblastoma: a case report in deciduous tooth. Oral Maxillofac Surg 2012; 17:145-9. [PMID: 22855308 DOI: 10.1007/s10006-012-0347-4] [Citation(s) in RCA: 8] [Impact Index Per Article: 0.6] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/05/2012] [Accepted: 07/18/2012] [Indexed: 10/28/2022]
Abstract
BACKGROUND The benign cementoblastoma is an odontogenic tumor originated from neoplastic cementoblasts, a rare lesion mainly associated to impacted and deciduous teeth. It affects mostly young people with an average age of 20 years old, and its preferred location is in the posterior region of the mandible; the lesion will present itself fused both radiologically and microscopically to a root of an erupted permanent tooth, and the anatomopathological diagnosis is obtained through the analysis of the piece sent together with the involved dental element. CASE REPORT The present study presents a case of cementoblastoma in the mandible involving the second deciduous molar tooth and preventing the eruption of the premolar tooth in a girl aged 11 years old. DISCUSSION This report discusses relevant aspects concerning clinical, radiographic, and histopathological characteristics and treatments.
Collapse
|