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Copyright ©The Author(s) 2015.
World J Cardiol. Oct 26, 2015; 7(10): 652-657
Published online Oct 26, 2015. doi: 10.4330/wjc.v7.i10.652
Figure 1
Figure 1 Non-enzymatic nitric oxide formation. One-electron reduction of nitrite (NO2-) to NO by ferrous heme proteins like hemoglobin in the blood or myoglobin in the heart can occur under conditions of low oxygen (O2); the nitrite-reductase activity of these proteins contributes to NOS independent NO formation. eNOS: Endothelial NO synthase; iNOS: Inducible NO synthase; nNOS: Neuronal NO synthase.