Comparative analysis of the predictive power of different endothelial progenitor cell phenotypes on cardiovascular outcome

Figure 1 Kaplan-Meier survival chart for the outcome of total major adverse cardiac event stratified by positive (dashed line) and negative (solid line) fluorescence-activated cell sorting analysis. A: CD34+CD133+ cells; B: CD34+KDR+; C: CD133+KDR+. MACE: Major adverse cardiac event.

Figure 2 Kaplan-Meier event free survival for the secondary endpoint of acute coronary syndrome (recurrent myocardial infarction or unstable angina) stratified by patients with positive fluorescence-activated cell sorting analysis (dashed line) vs patients with negative fluorescence-activated cell sorting analysis (solid line). A: CD34+CD133+ cells; B: CD34+KDR+; C: CD133+KDR+. ACS: Acute coronary syndrome.

Figure 3 Receiver operating characteristics curve analysis for the endpoint of acute coronary syndrome (recurrent myocardial infarction or unstable angina) as a function of the various endothelial progenitor cell populations. Only CD34+133+ correlated significantly with this outcome (P = 0.034); the P-value for CD34+KDR+ was 0.35 and for CD133+KDR+ was 0.19).