Copyright ©The Author(s) 2019.
World J Biol Chem. Nov 21, 2019; 10(3): 44-64
Published online Nov 21, 2019. doi: 10.4331/wjbc.v10.i3.44
Table 1 Table summarizing the interactions of hyaluronic acid binding protein 4 and serpin mRNA binding protein 1 with proteins related to the hormones progesterone and estradiol
GeneProteinBiological process referenceInteraction reference
UBR5E3 ubiquitin-protein ligase UBR5Progesterone receptor signaling pathway[158]SERBP1[22]
EIF2B2Translation initiation factor eIF-2B subunit betaOvarian follicle development[159]SERBP1[22]
FOSProto-oncogene c-FosResponse to progesterone stimulus[160]SERBP1[22]
PGRMC1Membrane-associated progesterone receptor component 1Progesterone receptor signaling pathway[161,162]SERBP1[149]
ESR2Estrogen receptor betaCellular response to estradiol stimulus[163]SERBP1, HABP4[22]
MDM2E3 ubiquitin-protein ligase Mdm2Cellular response to progesterone stimulus[164]SERBP1, HABP4[165]
NEDD4E3 ubiquitin-protein ligase NEDD4Progesterone receptor signaling pathway[166]SERBP1, HABP4[22]
ESR1Estrogen receptorCellular response to estradiol stimulus[163]SERBP1, HABP4 [22]
PKCProtein Kinase CCellular response to estradiol stimulus[167]HABP4[20]
p53Cellular tumor antigen p53Cellular response to estradiol stimulus[168]HABP4[21]
Table 2 Hyaluronic acid binding protein 4 and serpin mRNA binding protein 1 expression in different types of cancer
ProteinExpression/overexpressionCancer typesRef.
HABP4ExpressionHodgkin’s lymphomaKobarg et al[112]
HABP4ExpressionB-cell lymphatic leukemiaKobarg et al[112]
HABP4Expressionnon-Hodgkin-T-cell lymphomaKobarg et al[112]
HABP4ExpressionBladderKobarg et al[112]
SERBP1OverexpressionOvarianKoensgen et al[51]
SERBP1OverexpressionBreastSerce et al[144]
SERBP1OverexpressionColonWang et al[81]
SERBP1OverexpressionProstateGuo et al[145]
SERBP1OverexpressionLungSun et al[147]
SERBP1OverexpressionGlioblastomaHlavaty et al[146]