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World J Biol Chem. Mar 26, 2012; 3(3): 53-60
Published online Mar 26, 2012. doi: 10.4331/wjbc.v3.i3.53
Published online Mar 26, 2012. doi: 10.4331/wjbc.v3.i3.53
Biochemical analysis of the interactions of IQGAP1 C-terminal domain with CDC42
Sarah F Elliott, George Allen, David J Timson, School of Biological Sciences, Queen’s University Belfast, Medical Biology Centre, Belfast, BT9 7BL, United Kingdom
Author contributions: Elliott SF carried out all protein expression and purification and the crosslinking experiments; Elliott SF and Allen G jointly performed the surface plasmon resonance measurements; Elliott SF, Allen G and Timson DJ analysed these data; Timson DJ carried out the molecular modelling work, was responsible for the overall design of the study, obtained research grants to support the work and wrote the manuscript.
Supported by The Biotechnology and Biological Sciences Research Council (BBSRC), United Kingdom, No. BB/D000394/1; Action Cancer, Northern Ireland, United Kingdom, No. PG2 2005
Correspondence to: Dr. David J Timson, School of Biological Sciences, Queen’s University Belfast, Medical Biology Centre, 97 Lisburn Road, Belfast, BT9 7BL, United Kingdom. d.timson@qub.ac.uk
Telephone: +44-28-9097-5875 Fax: +44-28-9097-5877
Received: December 7, 2011
Revised: January 31, 2012
Accepted: February 7, 2012
Published online: March 26, 2012
Revised: January 31, 2012
Accepted: February 7, 2012
Published online: March 26, 2012
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