| For: | Lu ZJ, Deng SJ, Huang DG, He Y, Lei M, Zhou L, Jin P. Frontier of therapeutic antibody discovery: The challenges and how to face them. World J Biol Chem 2012; 3(12): 187-196 [PMID: 23275803 DOI: 10.4331/wjbc.v3.i12.187] |
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| URL: | https://www.wjgnet.com/1949-8454/full/v3/i12/187.htm |
| Number | Citing Articles |
| 1 |
Julius Grzeschik, Desislava Yanakieva, Lukas Roth, Simon Krah, Steffen C. Hinz, Adrian Elter, Tina Zollmann, Gerhard Schwall, Stefan Zielonka, Harald Kolmar. Yeast Surface Display in Combination with Fluorescence‐activated Cell Sorting Enables the Rapid Isolation of Antibody Fragments Derived from Immunized Chickens. Biotechnology Journal 2019; 14(4) doi: 10.1002/biot.201800466
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| 2 |
Starlynn C. Clarke, Biao Ma, Nathan D. Trinklein, Ute Schellenberger, Michael J. Osborn, Laure-Hélène Ouisse, Andrew Boudreau, Laura M. Davison, Katherine E. Harris, Harshad S. Ugamraj, Aarti Balasubramani, Kevin H. Dang, Brett Jorgensen, Heather Anne N. Ogana, Duy T. Pham, Payal P. Pratap, Preethi Sankaran, Ignacio Anegon, Wim C. van Schooten, Marianne Brüggemann, Roland Buelow, Shelley Force Aldred. Multispecific Antibody Development Platform Based on Human Heavy Chain Antibodies. Frontiers in Immunology 2019; 9 doi: 10.3389/fimmu.2018.03037
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| 3 |
Alexander Jarasch, Hans Koll, Joerg T. Regula, Martin Bader, Apollon Papadimitriou, Hubert Kettenberger. Developability Assessment During the Selection of Novel Therapeutic Antibodies. Journal of Pharmaceutical Sciences 2015; 104(6) doi: 10.1002/jps.24430
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| 4 |
Anizah Rahumatullah, Azimah Ahmad, Rahmah Noordin, Theam Soon Lim. Delineation of BmSXP antibody V-gene usage from a lymphatic filariasis based immune scFv antibody library. Molecular Immunology 2015; 67(2) doi: 10.1016/j.molimm.2015.07.040
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| 5 |
Bruno Villoutreix, Melaine Kuenemann, David Lagorce, Olivier Sperandio, Maria Miteva. In Silico Drug Discovery and Design. 2015; doi: 10.1201/b18799-21
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| 6 |
Shantanu V. Sule, Jason E. Fernandez, Vincent J. Mecozzi, Yana Kravets, William C. Yang, Pamela Feng, Suli Liu, Li Zang, Allan D. Capili, Tia B. Estey, Kapil Gupta. Assessing the Impact of Charge Variants on Stability and Viscosity of a High Concentration Antibody Formulation. Journal of Pharmaceutical Sciences 2017; 106(12) doi: 10.1016/j.xphs.2017.08.016
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| 7 |
Anizah Rahumatullah, Izzati Abdul Karim, Rahmah Noordin, Theam Lim. Antibody-Based Protective Immunity against Helminth Infections: Antibody Phage Display Derived Antibodies against BmR1 Antigen. International Journal of Molecular Sciences 2017; 18(11) doi: 10.3390/ijms18112376
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| 8 |
Casey K Hua, Albert T Gacerez, Charles L Sentman, Margaret E Ackerman, Yoonjoo Choi, Chris Bailey-Kellogg. Computationally-driven identification of antibody epitopes. eLife 2017; 6 doi: 10.7554/eLife.29023
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| 9 |
Nives Škrlj, Marko Dolinar. New engineered antibodies against prions. Bioengineered 2014; 5(1) doi: 10.4161/bioe.26069
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| 10 |
Guiying Pang, Ruixue Wang, Hongxu Yang, Mengya Chai, Yanzhe Gao, Sisi Chen, Ting Mao, Luheng Du, Yujia Lan, Shu Li, Jiale Xu, Panpan Cui, Ruqing Cheng, Yuxin Huang, Xuncui Wang, Yi Yang. A synthetic heavy chain variable domain antibody library (VHL) provides highly functional antibodies with favorable developability. Protein Science 2025; 34(4) doi: 10.1002/pro.70090
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| 11 |
Weizao Chen, Wei Li, Tianlei Ying, Yanping Wang, Yang Feng, Dimiter S. Dimitrov. Germlining of the HIV-1 broadly neutralizing antibody domain m36. Antiviral Research 2015; 116 doi: 10.1016/j.antiviral.2015.02.001
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| 12 |
Yoonjoo Choi, Christian Ndong, Karl E. Griswold, Chris Bailey-Kellogg. Computationally driven antibody engineering enables simultaneous humanization and thermostabilization. Protein Engineering Design and Selection 2016; 29(10) doi: 10.1093/protein/gzw024
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| 13 |
Andreas Lehmann, Josephine H F Wixted, Maxim V Shapovalov, Heinrich Roder, Roland L Dunbrack, Matthew K Robinson. Stability engineering of anti-EGFR scFv antibodies by rational design of a lambda-to-kappa swap of the VLframework using a structure-guided approach. mAbs 2015; 7(6) doi: 10.1080/19420862.2015.1088618
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| 14 |
Meghana T. Shivakumar, Sanjay Jayaram, Madhuchandra Kenchegowda, Riyaz Ali M. Osmani, Mohamed Rahamathulla, Shilpa Palaksha, Rutuja Harishchandra Yadav, H. V. Gangadharappa. Layered double hydroxides based nanomaterials: recent advances in drug delivery and biomedical applications. Health Nanotechnology 2025; 1(1) doi: 10.1186/s44301-025-00017-1
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| 15 |
Natalia Ponomarenko, Spyros D. Chatziefthimiou, Inna Kurkova, Yuliana Mokrushina, Yuliana Mokrushina, Anastasiya Stepanova, Ivan Smirnov, Marat Avakyan, Tatyana Bobik, Azad Mamedov, Vladimir Mitkevich, Alexey Belogurov, Olga S. Fedorova, Michael Dubina, Andrey Golovin, Victor Lamzin, Alain Friboulet, Alexander A. Makarov, Matthias Wilmanns, Alexander Gabibov. Role of κ→λ light-chain constant-domain switch in the structure and functionality of A17 reactibody. Acta Crystallographica Section D Biological Crystallography 2014; 70(3) doi: 10.1107/S1399004713032446
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| 16 |
Lukas Roth, Simon Krah, Janina Klemm, Ralf Günther, Lars Toleikis, Michael Busch, Stefan Becker, Stefan Zielonka. Genotype Phenotype Coupling. Methods in Molecular Biology 2020; 2070 doi: 10.1007/978-1-4939-9853-1_10
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| 17 |
Dimitrios Vlachakis, Sophia Kossida. Antibody Drug Conjugate Bioinformatics: Drug Delivery through the Letterbox. Computational and Mathematical Methods in Medicine 2013; 2013 doi: 10.1155/2013/282398
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| 18 |
James R. Apgar, Michelle Mader, Rita Agostinelli, Susan Benard, Peter Bialek, Mark Johnson, Yijie Gao, Mark Krebs, Jane Owens, Kevin Parris, Michael St. Andre, Kris Svenson, Carl Morris, Lioudmila Tchistiakova. Beyond CDR-grafting: Structure-guided humanization of framework and CDR regions of an anti-myostatin antibody. mAbs 2016; 8(7) doi: 10.1080/19420862.2016.1215786
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| 19 |
Patrice Douillard, Michael Freissmuth, Gerhard Antoine, Michael Thiele, Daniel Fleischanderl, Peter Matthiessen, Dirk Voelkel, Randolf J. Kerschbaumer, Friedrich Scheiflinger, Nicolas Sabarth. Optimization of an Antibody Light Chain Framework Enhances Expression, Biophysical Properties and Pharmacokinetics. Antibodies 2019; 8(3) doi: 10.3390/antib8030046
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| 20 |
Jan P. Bogen, Julius Grzeschik, Simon Krah, Stefan Zielonka, Harald Kolmar. Genotype Phenotype Coupling. Methods in Molecular Biology 2020; 2070 doi: 10.1007/978-1-4939-9853-1_16
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| 21 |
Max D. Overath, Suthimon Thumtecho, Esperanza Rivera-de-Torre, Melisa Benard-Valle, Darian S. Wolff, Rahmat Grahadi, Kasper H. Björnsson, Andreas S. H. Rygaard, Nils Hofmann, Jann Ledergerber, Anne Ljungars, Andreas H. Laustsen, Simon Olsson, Thomas J. Fryer, Timothy P. Jenkins.
Multiobjective V
H
H discovery through integrated high-throughput screening and AlphaFold3-guided structural prioritization
. Science Advances 2026; 12(40) doi: 10.1126/sciadv.aef5325
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| 22 |
Stefan Zielonka, Martin Empting, Julius Grzeschik, Doreen Könning, Caroline J Barelle, Harald Kolmar. Structural insights and biomedical potential of IgNAR scaffolds from sharks. mAbs 2015; 7(1) doi: 10.4161/19420862.2015.989032
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| 23 |
Yaswanth Kuthati, Ranjith Kumar Kankala, Chia-Hung Lee. Layered double hydroxide nanoparticles for biomedical applications: Current status and recent prospects. Applied Clay Science 2015; doi: 10.1016/j.clay.2015.04.018
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| 24 |
Yoonjoo Choi, Casey Hua, Charles L Sentman, Margaret E Ackerman, Chris Bailey-Kellogg. Antibody humanization by structure-based computational protein design. mAbs 2015; 7(6) doi: 10.1080/19420862.2015.1076600
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| 25 |
Xiaofeng Li, Qiana Mendez, Cassandra Chapados, Felicity Acca, Holly Driscoll, Jason Oliveira, Jun Liu, Kezzia Jones, Mary Ferguson, Ryan L. Wallace, Sergei Bibikov, Troy Lionberger, Kevin J. Harvey, Michael P. Weiner, Greg Mirando. Site-directed antibodies targeting driver mutations of the KRAS protein. New Biotechnology 2025; 87 doi: 10.1016/j.nbt.2025.04.003
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| 26 |
. 2013; doi: 10.70675/6783b8c7z73fbz412fzbcf1zf4d15d96dd04
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| 27 |
Bruno O. Villoutreix, Melaine A. Kuenemann, Jean‐Luc Poyet, Heriberto Bruzzoni‐Giovanelli, Céline Labbé, David Lagorce, Olivier Sperandio, Maria A. Miteva. Drug‐Like ProteinProtein Interaction Modulators: Challenges and Opportunities for Drug Discovery and Chemical Biology. Molecular Informatics 2014; 33(6-7) doi: 10.1002/minf.201400040
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| 28 |
Mateusz Makuch, Josine van Beek, Carla A. Wijbrandts, Marja Aalbers, Philippe Stas, Alexander B. Meijer, Anja ten Brinke, Theo Rispens, Paul Peter Tak, Gertjan Wolbink, Janine Schuurman, Paul W. H. I. Parren, S. Marieke van Ham. The TNFα-binding domain of the therapeutic antibody adalimumab elicits CD4 T-cell responses in rheumatoid arthritis patients. Frontiers in Immunology 2025; 16 doi: 10.3389/fimmu.2025.1549781
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| 29 |
Achim Doerner, Laura Rhiel, Stefan Zielonka, Harald Kolmar. Therapeutic antibody engineering by high efficiency cell screening. FEBS Letters 2014; 588(2) doi: 10.1016/j.febslet.2013.11.025
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