Sixth and seventh tumor-node-metastasis staging system compared in gastric cancer patients

Table 1 Tumor-node-metastasis staging system 6^th and 7^th edition

TNM staging system 6th edition				TNM staging system 7th edition
Stage	T	N	M	Stage	T	N	M
0	Tis	N0	M0	0	Tis	N0	M0
IA	T1	N0	M0	IA	T1	N0	M0
IB	T1	N1	M0	IB	T2	N0	M0
	T2a	N0	M0		T1	N1	M0
	T2b	N0	M0	IIA	T3	N0	M0
II	T1	N2	M0		T2	N1	M0
	T2a	N1	M0		T1	N2	M0
	T2b	N1	M0	IIB	T4a	N0	M0
	T3	N0	M0		T3	N1	M0
IIIA	T2a	N2	M0		T2	N2	M0
	T2b	N2	M0		T1	N3	M0
	T3	N1	M0	IIIA	T4a	N1	M0
	T4	N0	M0		T3	N2	M0
IIIB	T3	N2	M0		T2	N3	M0
IV	T4	N1	M0	IIIB	T4b	N0, N1	M0
	T4	N2	M0		T4a	N2	M0
	T4	N3	M0		T3	N3	M0
	T1	N3	M0	IIIC	T4a	N3	M0
	T2	N3	M0		T4b	N2, N3	M0
	T3	N3	M0	IV	AnyT	AnyN	M1
	Any T	Any N	M1

Table 2 Univariate survival analysis of clinicopathologic variables in 241 patients n (%)

Variable	n(%)	5-year overall survival rate (%)	P value
All	241	52.80
Sex			0.740
Female	116 (48.1)	50.40
Male	125 (51.9)	54.30
Age (yr)			0.000
1 ( ≤50)	14 (5.8)	78.60
2 (51-60)	18 (7.5)	32.00
3 (61-70)	78 (32.3)	57.50
4 (71-80)	87 (36.1)	57.30
5 (> 80)	44 (18.3)	35.20
Site			0.006
S	40 (16.6)	33.30
M	50 (20.7)	70.80
I	150 (62.2)	51.50
Surgery			0.400
Total gastrectomy	191 (79.3)	53.10
Subtotal gastrectomy	50 (20.7)	52.60
Lauren			0.500
Intestinal	150 (62.2)	56.50
Diffuse	58 (24.0)	48.50
Mixed	15 (6.2)	33.90
T stage (6th edition)			< 0.0001
T1	64 (26.6)	86.20
T2	135 (56.0)	45.40
T3	37 (15.3)	23.30
T4	5 (2.1)	0.00
T stage (7th edition)			< 0.0001
T1	64 (26.6)	86.20
T2	33 (13.7)	71.00
T3	102 (42.3)	37.30
T4	42 (17.4)	20.50
N stage (6th edition)			< 0.0001
N0	81 (33.6)	77.30
N1	73 (30.3)	55.70
N2	50 (20.7)	27.60
N3	37 (15.4)	22.90
N stage (7th edition)			< 0.0001
N0	81 (33.6)	77.30
N1	39 (16.2)	67.50
N2	35 (14.5)	43.00
N3	86 (35.7)	25.90
Stage (6th edition)			< 0.0001
I	87 (36.1)	76.40
II	59 (24.5)	61.50
III	55 (22.8)	24.40
IV	40 (16.6)	21.20
Stage (7th edition)			< 0.0001
I	70 (29)	85.60
II	56 (23.3)	61.50
III	115 (47.7)	27.00
Lymph node ratio			< 0.0001
I (0)	81 (33.6)	77.30
II (0.01-0.09)	41 (17.1)	65.40
III (0.1-0.25)	50 (20.7)	44.50
IV (> 0.25)	69 (28.6)	21.00

S: Superior; M: Middle; I: Inferior.

Table 3 Stage migration from the sixth to seventh edition of the tumor-node-metastasis system

	7th edition TNM
6th edition TNM	Stage (patients)	I	II	III	P
	I	70	17		0.004
	II		39	20	0.040
	III			55
	IV			40
	P		0.09	P(II-III) = 0.3P(IV-III) = 0.1

TNM: Tumor-node-metastasis.