Copyright ©2010 Baishideng.
World J Gastrointest Surg. Mar 27, 2010; 2(3): 61-69
Published online Mar 27, 2010. doi: 10.4240/wjgs.v2.i3.61
Table 1 Methods for the assessment of intestinal barrier integrity status and intestinal barrier function loss
TestMeasured inIndicative forTissue specificity
I-FABPBlood or urineIntestinal epithelial integrityYes (predominantly proximal small gut)
Single sample
I-BABPBlood or urineIntestinal epithelial integrityYes (predominantly ileum)
Single sample
L-FABPBlood or urineIntestinal epithelial integrityNo
Single sample
GST-αBloodIntestinal epithelial integrityNo
Single sample
Claudin 3UrineParacellular integrityNo
Single sample
Dual Sugar TestUrineFunctional intestinal barrier functionYes
5 h collection
PEGUrineFunctional intestinal barrier functionYes
6 h collection
51Cr-EDTAUrineFunctional intestinal barrier functionYes
24 h collection
LAL-assayBloodIntestinal barrier functionN/A
Single sample
EndoCAbBloodIntestinal barrier functionN/A
Single sample
D-LactateBloodIntestinal barrier functionYes
Single sample