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Retrospective Study
Copyright: ©Author(s) 2026.
World J Gastrointest Surg. Nov 27, 2026; 18(11): 124340
Published online Nov 27, 2026. doi: 10.4240/wjgs.124340
Table 1 Patient demographics and baseline characteristics, n (%)

Total (n = 31)
ModVAC (n = 16)
No-ModVAC (n = 15)
P value
Sex
Male19 (64.5)10 (62.5)10 (66.7)
Female11 (35.5)6 (37.5)5 (33.3)0.801
Age (mean)5961570.332
Comorbidities
DM7 (23.3)5 (33.3)2 (13.3)0.191
CAD7 (23.3)3 (20)4 (26.7)0.661
Smoking21 (70)10 (66.7)11 (73.3)0.691
ASA score
226 (83.8)14 (87.5)12 (80)
35 (16.2)2 (12.5)3 (20)0.593
Pathology
Adenocarcinoma15 (48.4)9 (56.3)6 (40)
SCC14 (45.2)6 (37.5)8 (53.3)
Benign2 (6.5)1 (6.3)1 (6.7)0.651
Tumor location
Middle2 (6.5)02 (13.3)
Distal21 (67.7)11 (68.6)10 (66.7)
GEJ8 (25.8)5 (31.3)3 (20)0.221
Neoadjuvant therapy
No12 (38.7)5 (31.3)7 (46.7)
Yes19 (61.3)11 (68.8)8 (53.3)0.371
Table 2 Modified, endoscopy-independent prophylactic vacuum-assisted closure system application parameters
MaximumMinimumMean
Aspirated fluid, mL18000489
Duration of application, days1124.3
Length of hospital stay, days56720.4
Table 3 Surgical approach and clinical outcomes in modified, endoscopy-independent prophylactic vacuum-assisted closure vs non-modified, endoscopy-independent prophylactic vacuum-assisted closure patients, n (%)

Total (n = 31)
ModVAC (n = 16)
No-ModVAC (n = 15)
P value
Operation type
Minimally invasive8 (25.8)7 (43.8)1 (6.7)
Open13 (41.9)3 (18.8)10 (66.7)
Hybrid10 (32.3)6 (37.5)4 (26.7)0.011
Anastomosis
Linear stapler12 (38.7)6 (37.5)6 (40)
Circular stapler14 (45.2)10 (62.5)4 (26.7)
Hand sewn5 (16.1)05 (33.3)0.021
Jejunostomy15 (48.4)8 (50)7 (46.7)0.851
Postoperative length of stay (mean days)20.820.421.30.882
Anastomotic leak
Absent21 (67.7)12 (75)9 (60)
Present10 (32.3)4 (25)6 (40)0.371
Clavien-Dindo
Grade I-IIIa10 (62.5)6 (66.7)4 (57.1)
Grade IIIb-IV6 (37.5)3 (33.3)3 (42.9)0.691


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